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Study: Hydroxychloroquine has no effect on abnormal heart rhythm in lupus patients with CKD

New research shows that adults with lupus who take the antimalarial drug, hydroxychloroquine, do not have any differences in their corrected QT (QTc) intervals, an electrocardiogram (EKG) measurement of the heart's electrical signals, even if they have chronic kidney disease (CKD), a complication of lupus that can be associated with increased levels of the medication.

9 Nov 2020

Researchers monitor effects of COVID-19 outbreak on care of cancer patients

Fewer breast and colorectal cancer diagnoses have been made in the Netherlands due to the COVID-19 crisis this spring. The decline in the number of diagnoses was more abundant in age groups invited to national population screening programmes, as compared to other age groups.

9 Nov 2020

National Covid-19 Resilience Programme in the UK would support older people through pandemic

Public health agencies across the UK should launch a National Covid-19 Resilience Programme to support older people through the pandemic and to keep them healthy and resilient over the winter - that's the recommendation from a leading group of scientists and clinicians working in the fields of physiology, nutrition and physiotherapy.

9 Nov 2020

Researchers identify new strategy to combat loss of skeletal muscle mass

Researchers at the University of São Paulo (USP) in Brazil have shown for the first time that stimulating expression of a protein naturally produced by the human body can be a strategy to combat loss of skeletal muscle mass, which happens normally with aging but can intensify in cases of neurodegenerative or inflammatory disease, or in patients who spend long periods in intensive care units (ICUs).

9 Nov 2020

New strategy for designing COVID-19 antiviral drugs to inhibit key viral protein

SARS-CoV-2, the respiratory virus that causes COVID-19, attacks the body in multiple steps. Gaining entry into cells deep within the lungs and hijacking the human host cell's machinery to churn out copies of itself are two of the earliest steps -- both essential for viral infection.

9 Nov 2020

Researchers analyze metrics of cognitive decline in diverse Latinx populations

Alzheimer's disease and related dementias (ADRD) are degenerative brain diseases that affect over 5.8 million people in the U.S. Rates of ADRD are higher among Black and Latinx individuals compared to non-Latinx white individuals.

9 Nov 2020

Air pollution accounts for premature deaths from cardiovascular disease

In a current opinion article "Reduction of environmental pollutants for prevention of cardiovascular disease: it's time to act", published in the European Heart Journal this week.

9 Nov 2020

Pre-existing antibodies created during COVID-19 may protect children against new pandemic strain

Researchers at the Francis Crick Institute and University College London have found that some antibodies, created by the immune system during infection with common cold coronaviruses, can also target SARS-CoV-2 and may confer a degree of protection against the new viral strain.

9 Nov 2020

Study: Photoresponsive derivatives of Taxol allow light-based control of microtubule cytoskeleton

Ludwig-Maximilians-Universitaet (LMU) in Munich researchers have developed photoresponsive derivatives of the anticancer drug Taxol, which allow light-based control of cytoskeleton dynamics in neurons. The agents can optically pattern cell division and may elucidate how Taxol acts.

9 Nov 2020

Patients diagnosed with Parkinson's disease may actually have NIID, shows study

A joint study by the National Neuroscience Institute (NNI) and Singapore General Hospital (SGH) revealed that patients who have been diagnosed with Parkinson's disease might actually have NIID instead.

9 Nov 2020

Study explores why attractive food seems healthier to consumers

A researcher from University of Southern California published a new paper in the Journal of Marketing that explores whether attractive food might seem healthier to consumers.

9 Nov 2020

Researchers to develop new optogenetic tools for biology and medicine

The European Research Council (ERC) is providing 10 million euros in funding for an interdisciplinary, collaborative project in the structural and biophysical analysis of selected photoreceptors and their development into "OptoGPCRs", light-controlled molecular switches with a wide range of applications in biology and medicine.

8 Nov 2020

Successful containment of COVID-19 in a Brazilian archipelago

The team of researchers in May 2020, headed by Ligia Regina Franco Sansigolo Kerr and Prof Costa Mendes, aimed to discuss and report the various control measures taken by FNA authorities in order to reduce the spread of SARS-CoV-2 virus in the Fernando de Noronha Archipelago (FNA). Their research is published on the preprint server medRxiv.

8 Nov 2020

New strategy shows promises for treating RNA-repeat expansion disorders

A new strategy for treating a variety of diseases known as RNA-repeat expansion disorders, which affect millions of people, has shown promise in proof-of-principle tests conducted by scientists at Scripps Research.

8 Nov 2020

Study shows SARS-CoV-2 direct heart muscle cell infection, cell death, loss of contractility

In the study, published on the pre-print journal bioRxiv, the researchers revealed that SARS-CoV-2-infected EHTs manifested the typical characteristics of myocarditis or heart inflammation. These include the stimulation of immune cells, heart cell death, and decreased contractile force generation.

8 Nov 2020

Researchers launch clinical trial to assess therapeutic drug monitoring for patients with inflammatory diseases

New research presented at ACR Convergence, the American College Rheumatology's annual meeting, showed that patients with rheumatic diseases whose infliximab treatment was individually assessed and adjusted with a new strategy called therapeutic drug monitoring did not achieve remission at higher rates compared to those who received standard care.

8 Nov 2020

Researchers compare rhesus and cynomolgus macaques for SARS-CoV-2 vaccine trials

A team of researchers at the Biomedical Primate Research Centre based in the Netherlands have aimed to determine the effects of the SARS-CoV-2 pathogen on these monkeys and, subsequently, whether they make good animal models for future research in the area.

8 Nov 2020

Study suggests honey and Nigella sativa expedites viral clearance in COVID-19 patients

A team of researchers from various institutes across Pakistan, Chile, Canada, and the USA recently conducted a clinical trial to investigate the potential effectiveness of a combination of honey and Nigella sativa (HNS) in treating COVID-19 patients. Their study is published on the preprint server medRxiv prior to the scientific peer review process.

8 Nov 2020

Study suggests SARS-CoV-2 mutation fingerprints could be used for molecular contact tracing

In a recent groundbreaking study, researchers from Stanford University demonstrated the potential of multiplexed targeted next-generation sequencing assay for detecting SARS-CoV-2 genetic fingerprints used in mutation profiling, with the potential of massive scalability required for population studies. The findings are currently available on the medRxiv preprint server.

8 Nov 2020

Mobile phone contamination could be part of SARS-CoV-2 transmission chain in hospitals, Brazil case study suggests

Researchers conducting a study at a coronavirus disease 2019 (COVID-19) intensive care unit (ICU) in São Paulo, Brazil, have warned that infection control guidelines need to include a universal policy regarding the disinfection of mobile phones in the hospital setting.

8 Nov 2020

Medical Research News

Study: Hydroxychloroquine has no effect on abnormal heart rhythm in lupus patients with CKD

Researchers monitor effects of COVID-19 outbreak on care of cancer patients

National Covid-19 Resilience Programme in the UK would support older people through pandemic

Researchers identify new strategy to combat loss of skeletal muscle mass

New strategy for designing COVID-19 antiviral drugs to inhibit key viral protein

Researchers analyze metrics of cognitive decline in diverse Latinx populations

Air pollution accounts for premature deaths from cardiovascular disease

Pre-existing antibodies created during COVID-19 may protect children against new pandemic strain

Study: Photoresponsive derivatives of Taxol allow light-based control of microtubule cytoskeleton

Patients diagnosed with Parkinson's disease may actually have NIID, shows study

Study explores why attractive food seems healthier to consumers

Researchers to develop new optogenetic tools for biology and medicine

Successful containment of COVID-19 in a Brazilian archipelago

New strategy shows promises for treating RNA-repeat expansion disorders

Study shows SARS-CoV-2 direct heart muscle cell infection, cell death, loss of contractility

Researchers launch clinical trial to assess therapeutic drug monitoring for patients with inflammatory diseases

Researchers compare rhesus and cynomolgus macaques for SARS-CoV-2 vaccine trials

Study suggests honey and Nigella sativa expedites viral clearance in COVID-19 patients

Study suggests SARS-CoV-2 mutation fingerprints could be used for molecular contact tracing

Mobile phone contamination could be part of SARS-CoV-2 transmission chain in hospitals, Brazil case study suggests

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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