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Research describes novel molecules designed to treat or prevent COVID-19 infection

Neoleukin Therapeutics, Inc., "Neoleukin" (NASDAQ:NLTX), a biopharmaceutical company utilizing sophisticated computational methods to design de novo protein therapeutics, today announced the publication in Science of research describing novel molecules designed to treat or prevent infection by the virus that causes COVID-19, SARS-CoV-2.

6 Nov 2020

COVID-19 hospitalizations and deaths skew towards older males of non-European ancestry

A team of researchers recently investigated the genetic determinants of COVID-19 risk and severity in humans.

6 Nov 2020

Deciphering heart-brain talk may help unlock the key to cardiovascular disease

The crosstalk of the heart and brain is continuous and deciphering those messages may help researchers unlock the key to cardiovascular disease, says Deeptankar DeMazumder, MD, PhD, assistant professor in the University of Cincinnati College of Medicine.

6 Nov 2020

Study shows iscan method could be effective for rapid COVID-19 testing

A simple COVID-19 test kit combines virus amplification with a CRISPR-Cas system for effective SARS-CoV-2 detection. The kit, called iSCAN, uses reagents that can be locally manufactured.

6 Nov 2020

New resource can help predict drug sensitivity and optimize therapeutic strategies

Through large-scale profiling of protein changes in response to drug treatments in cancer cell lines, researchers at The University of Texas MD Anderson Cancer Center have generated a valuable resource to aid in predicting drug sensitivity, to understand therapeutic resistance mechanisms and to identify optimal combination treatment strategies.

6 Nov 2020

Study uses non-invasive technique to help veterans with depression, concussion

Studies using repetitive transcranial magnetic stimulation (rTMS), a non-invasive technique, to help veterans and active-duty service members living with depression, post-traumatic stress disorder (PTSD), and other lasting consequences of concussion have shown promise.

6 Nov 2020

Switching from cigarettes to tobacco heating products may reduce risk of developing diseases

New research by BAT has found that smokers who switched completely from smoking cigarettes to using BAT's flagship tobacco heating product (THP), glo, substantially reduced their exposure to certain cigarette smoke toxicants over three months.

6 Nov 2020

Study may help develop effective drugs against COVID-19

Scientists at the University of Cambridge, in collaboration with Justus-Liebig University, Germany, have uncovered how the genome of SARS-CoV-2 - the coronavirus that causes COVID-19 - uses genome origami to infect and replicate successfully inside host cells.

5 Nov 2020

Early administration of combination therapy can be effective for treating stomach cancer

Immunotherapy for stomach cancer may work better if the therapy is delivered earlier in the course of disease and in combination with standard chemotherapy, a new study from researchers at Columbia University Vagelos College of Physicians and Surgeons suggests.

5 Nov 2020

Unrelated mutations can lead to false-positive results in men with advanced prostate cancer

Unrelated mutations, when present in the blood, can lead to false-positive results in men with advanced prostate cancer who are undergoing liquid biopsies.

5 Nov 2020

Study reveals new therapeutic approach for superbug infections

A research team led by Professor Hongzhe SUN, Chair Professor from the Department of Chemistry, Faculty of Science, in collaboration with Dr Pak-Leung HO, Director of the HKU Carol Yu Centre for Infection from the Department of Microbiology, Li Ka Shing Faculty of Medicine.

5 Nov 2020

Researchers offer solutions to overcome strength-training gender gap

Strength training is an important part of any exercise routine, but some women may not be getting the recommended hours. New Penn State research discovered some of the barriers preventing women from strength training, as well as some solutions to overcoming those obstacles.

5 Nov 2020

Study: Blocking energy pathway helps reduce graft-versus-host disease

MUSC Hollings Cancer Center researchers identified that blocking an alternative energy pathway for T-cells after hematopoietic stem cell transplant helps reduce graft-versus-host disease (GVHD) in an animal model of leukemia.

5 Nov 2020

Anxiety disorders increase among US citizens during COVID-19 pandemic

Scientists from the University of North Carolina and City University New York have recently revealed that a majority of United States citizens have suffered from anxiety disorders amid the coronavirus disease 2019 (COVID-19) pandemic. Financial adversity is one of the major causative factors for anxiety symptoms. The study is currently available on the medRxiv* preprint server.

5 Nov 2020

A digital CRISPR-based method for quick detection and absolute quantification of SARS-CoV-2

In a recent medRxiv* preprint manuscript, researchers from Singapore and the United States report the development of a digital CRISPR method for the sensitive, specific, and rapid detection of viral nucleic acids at a constant temperature, which could be exploited for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

5 Nov 2020

New Zealand case study shows room for improvement in genomic sequencing of COVID-19 outbreaks

Researchers in New Zealand, the United States and Australia have demonstrated the effectiveness of real-time genomic sequencing at tracking the re-emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in New Zealand, in August this year.

5 Nov 2020

Pre-existing anti-IFN autoantibodies may worsen COVID-19 in lupus patients

“Our observations suggest that the presence of these autoantibodies may predispose SLE patients to infection with SARS-CoV-2 with a more severe presentation and represent an additional risk factor in this patient population,” write Sarthak Gupta and colleagues from the National Institute of Arthritis and Musculoskeletal and Skin Diseases in Bethesda, Maryland.

5 Nov 2020

Foods that cause inflammation tied to a higher risk of cardiovascular disease

A new study by researchers at the Harvard T.H. Chan School of Public Health has found that diets high in red and processed meat, sugary beverages, and refined grains promote inflammation in the body and increase the subsequent risk of heart disease and stroke.

5 Nov 2020

Persistent and extensive lung damage seen in COVID-19 patients

A team of researchers at the University of Trieste in Italy aimed to determine the extent and the causes of lung damage from COVID-19 to better understand the pathological correlates of the disease.

5 Nov 2020

Llama antibodies could be a potent nanoweapon against COVID-19

Today in Science, researchers at the University of Pittsburgh School of Medicine describe a new method to extract tiny but extremely powerful SARS-CoV-2 antibody fragments from llamas, which could be fashioned into inhalable therapeutics with the potential to prevent and treat COVID-19.

5 Nov 2020

Medical Research News

Research describes novel molecules designed to treat or prevent COVID-19 infection

COVID-19 hospitalizations and deaths skew towards older males of non-European ancestry

Deciphering heart-brain talk may help unlock the key to cardiovascular disease

Study shows iscan method could be effective for rapid COVID-19 testing

New resource can help predict drug sensitivity and optimize therapeutic strategies

Study uses non-invasive technique to help veterans with depression, concussion

Switching from cigarettes to tobacco heating products may reduce risk of developing diseases

Study may help develop effective drugs against COVID-19

Early administration of combination therapy can be effective for treating stomach cancer

Unrelated mutations can lead to false-positive results in men with advanced prostate cancer

Study reveals new therapeutic approach for superbug infections

Researchers offer solutions to overcome strength-training gender gap

Study: Blocking energy pathway helps reduce graft-versus-host disease

Anxiety disorders increase among US citizens during COVID-19 pandemic

A digital CRISPR-based method for quick detection and absolute quantification of SARS-CoV-2

New Zealand case study shows room for improvement in genomic sequencing of COVID-19 outbreaks

Pre-existing anti-IFN autoantibodies may worsen COVID-19 in lupus patients

Foods that cause inflammation tied to a higher risk of cardiovascular disease

Persistent and extensive lung damage seen in COVID-19 patients

Llama antibodies could be a potent nanoweapon against COVID-19

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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