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New lipid derivatives of Remdesivir have higher anti-coronavirus activity

In a fascinating new preprint paper published on bioRxiv* in August 2020, the researchers report “the synthesis and antiviral evaluation of three novel lipophilic prodrugs of RVn-monophosphate that are substantially more active than Remdesivir in cells infected with SARS-CoV-2.” These could be of immense use in treating COVID-19 patients early and helping to end transmission.

30 Aug 2020

Rabbits susceptible to SARS-CoV-2: Red flag for potential virus reservoir

A new study by scientists in the Netherlands and published on the preprint server bioRxiv* in August 2020 shows that the severe acute respiratory coronavirus-2 (SARS-CoV-2) can infect rabbits, which opens the door for possible circulation in rabbit farms and another potential source of animal to human SARS-CoV-2 infection. This finding calls for urgent research on the prevalence of the virus in farmed rabbits.

30 Aug 2020

Using SARS-CoV-2 epitope to construct a vaccine

A new study published on the preprint server bioRxiv* in August 2020 reports the use of prediction and advanced simulation techniques to identify a novel T cell epitope on the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that could serve as the basis for a customized vaccine with broad-based efficacy.

30 Aug 2020

SARS-CoV-2 Neucleocapside (N) protein is heavily glycosylated

However, the nucleocapsid (N) protein is also extremely abundant and, therefore, a useful target for both vaccine and diagnostic test development. A new study published on the preprint server bioRxiv in August 2020 reveals the structure of this protein, a valuable step in using it for these purposes.

30 Aug 2020

Severe and fatal COVID-19 is rare in children

Now, a new study by researchers at the Universities of Edinburgh and Liverpool, Imperial College London, and the Royal Hospital for Children, Glasgow in the United Kingdom has shown that children and teenagers are less likely than adults to develop severe COVID-19 or die from the disease.

30 Aug 2020

Evidence of SARS-CoV-2 spreading in an airplane toilet

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease (COVID-19), is still actively spreading like wildfire, with nearly 300,000 new infections reported daily across the globe. Early on in the outbreak in China, scientists said that the virus could spread through respiratory droplets, when a person coughs, sneezes, or speaks.

30 Aug 2020

Atheists and agnostics more likely to be better sleepers than Catholics, Baptists

A new study of sleep, religious affiliation, and perceptions of heaven found that atheists and agnostics are significantly more likely to be better sleepers than Catholics and Baptists.

28 Aug 2020

Sleep loss unleashes anger, shows study

Feeling angry these days? New research suggests that a good night of sleep may be just what you need.

28 Aug 2020

Clinicians may have to look beyond opioids to tackle nation’s substance use epidemic

Overcoming the nation's opioid epidemic will require clinicians to look beyond opioids, new research from Oregon Health & Science University suggests.

28 Aug 2020

Host tissue T cells play a previously unappreciated role in acute graft-versus-host disease

Allogenic hematopoietic stem cell transplantation (HSCT) is a procedure that infuses a donor's healthy blood-forming stem cells into a recipient as part of a potentially curative therapy for cancer.

28 Aug 2020

International research network aims to understand how animals use odors to guide behavior

The University of Colorado Boulder will lead a groundbreaking new international research network dubbed Odor2Action starting this fall.

28 Aug 2020

Using deep learning to study how mental disorders affect the brain

Georgia State University researchers are working to harness deep learning and artificial intelligence to learn more about how mental illness and other disorders affect the brain.

28 Aug 2020

Poultry farmers play active role in the dissemination of avian influenza

Small-scale poultry farmers in Vietnam tend to respond to viral outbreaks of highly pathogenic avian influenza (HPAI) by rapidly selling their birds as a way to avoid financial loss, according to a new study by an international team of researchers.

28 Aug 2020

Household food insecurity linked to higher obesity risk for infants

Infants from households reporting very low "food security," a measure of access to adequate and healthy meals, tend to weigh more than those from households with relatively high food security, suggests a new study led by a researcher at Johns Hopkins Bloomberg School of Public Health.

28 Aug 2020

Virginia Tech researcher wins NIH award to study possible treatments for metastatic breast cancer

Eli Vlaisavljevich, an assistant professor of biomedical engineering and mechanics at Virginia Tech, received a Trailblazer Award from the National Institute of Biomedical Imaging and Bioengineering of the National Institutes of Health to research possible treatments for metastatic breast cancer.

28 Aug 2020

New biomaterials from spider silk eliminate risk of infection and facilitate healing process

New biomaterials developed at the University of Bayreuth eliminate risk of infection and facilitate healing processes.

28 Aug 2020

Study may help explain the symptoms and organs involved with SARS-CoV-2 infection

A study of a gateway receptor for SARS-CoV-2 led by Walter Lukiw, PhD, Professor of Neuroscience, Neurology and Ophthalmology at LSU Health New Orleans' Neuroscience Center of Excellence and School of Medicine, may help explain the wide variety of symptoms and organs involved with SARS-CoV-2 infection and COVID-19.

28 Aug 2020

Prosthetic breast reconstruction outcomes do not deteriorate over time, shows study

Breast reconstruction is an important option for women undergoing mastectomy, and a two-stage approach using implants is by far the most common reconstruction technique.

28 Aug 2020

Study shows benefits of new palliative care model for patients with neurological conditions

Findings from a large-scale clinical trial testing a new palliative care model have shown to be lower cost, viewed positively by patients and their carers while showing no difference in patient-reported outcomes when compared with standard care.

28 Aug 2020

Study analyzes link between maternal insecticide use during pregnancy and neonatal jaundice

The data of 61,751 pregnant women, out of approximately 100,000 collected by the Japan Environment and Children's Study analyzed the association between the maternal usage of insecticides and insect repellents during pregnancy and neonatal hyperbilirubinemia.

28 Aug 2020

Medical Research News

New lipid derivatives of Remdesivir have higher anti-coronavirus activity

Rabbits susceptible to SARS-CoV-2: Red flag for potential virus reservoir

Using SARS-CoV-2 epitope to construct a vaccine

SARS-CoV-2 Neucleocapside (N) protein is heavily glycosylated

Severe and fatal COVID-19 is rare in children

Evidence of SARS-CoV-2 spreading in an airplane toilet

Atheists and agnostics more likely to be better sleepers than Catholics, Baptists

Sleep loss unleashes anger, shows study

Clinicians may have to look beyond opioids to tackle nation’s substance use epidemic

Host tissue T cells play a previously unappreciated role in acute graft-versus-host disease

International research network aims to understand how animals use odors to guide behavior

Using deep learning to study how mental disorders affect the brain

Poultry farmers play active role in the dissemination of avian influenza

Household food insecurity linked to higher obesity risk for infants

Virginia Tech researcher wins NIH award to study possible treatments for metastatic breast cancer

New biomaterials from spider silk eliminate risk of infection and facilitate healing process

Study may help explain the symptoms and organs involved with SARS-CoV-2 infection

Prosthetic breast reconstruction outcomes do not deteriorate over time, shows study

Study shows benefits of new palliative care model for patients with neurological conditions

Study analyzes link between maternal insecticide use during pregnancy and neonatal jaundice

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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