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Study shows nitrate supplementation improves diaphragm's function in elderly people

New research published today in The Journal of Physiology shows that nitrate improves function in the diaphragm, the muscle involved in coughing and breathing, by improving power.

17 Aug 2020

Coronacept - A trap-and-destroy molecule against SARS-CoV-2

A new study published on the preprint server bioRxiv* in August 2020 reports a novel engineered molecule based on human and other mammalian orthologues of ACE2 fused with the Fc part of the antibody. This molecule interacts more tightly with the viral receptor-binding domain (RBD) to constitute a powerful immunoadhesin that targets the virus for destruction.

17 Aug 2020

Targeting SARS-CoV-2 with off-the-shelf CAR-NK cells

The current COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread and cause disease and death in many countries even today. At present, there is no effective treatment. A recent study published on the preprint server bioRxiv in August 2020 reports the potential of a new class of drugs called CAR NK cells, which could be used off-the-shelf to treat this disease.

17 Aug 2020

Potential inhibitors of SARS-CoV-2 identified

Now, a new study published on the preprint server bioRxiv in August 2020 reports the discovery of two inhibitors of the helicase enzyme, which is essential for viral replication and the most highly conserved non-structural coronavirus (CoV) protein.

16 Aug 2020

ARDS may not be the primary lung iInjury in COVID-19

A new Italian study published on the preprint server medRxiv in August 2020 shows that this may not be an adequate explanation, since ARDS is a nonspecific diagnosis. Instead, they say, antemortem lung biopsy shows a “Covid pattern” of acute lung injury, which could guide the application of therapeutics.

16 Aug 2020

Scientists reveal most likely order of COVID-19 symptoms

Now, a team of researchers at the University of Southern California (USC) has revealed the order of symptoms often experienced by those who infected with SARS-CoV-2. Knowing the order of the symptoms may help the patients seek medical help immediately. The research is published in the journal Frontiers in Public Health.

16 Aug 2020

U.S. scientists to create coronavirus strain for human challenge trials

Now, a team of scientists in the United States plans to create a coronavirus strain that can be used for human challenge trials, a controversial type of study wherein health volunteers would be vaccinated and intentionally infected with the virus.

16 Aug 2020

SARS-CoV-2 spike pocket is a putative target for antiviral design

In a methodologically rigorous study, researchers from the University of Oxford have recently shown how the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein harbors a lipid-binding pocket which modulates the stability of the prefusion trimer and provides conformational shielding from antibodies. Their findings are currently freely available on the bioRxiv* preprint server.

16 Aug 2020

Multiphase program provides valuable lessons for advancing the fight against malaria

The intensive implementation of currently available tools to fight malaria can achieve a drastic reduction in disease burden, but is not enough to interrupt its transmission.

15 Aug 2020

New study challenges hypothesis underlying the sensitivity of mammalian auditory system

A new study from the University of Colorado Anschutz Medical Campus challenges a decades-old hypothesis on adaptation, a key feature in how sensory cells of the inner ear (hair cells) detect sound.

15 Aug 2020

Historical redlining associated with adverse birth outcomes

Past discriminatory housing practices may play a role in perpetuating the significant disparities in infant and maternal health faced by people of color in the U.S., suggests a new study by researchers at the University of California, Berkeley.

15 Aug 2020

Number of in-person health care visits not linked to COVID-19 infection in pregnant patients

In the spring of 2020, as Massachusetts experienced a surge in COVID-19 cases in the Boston area, four area hospitals conducted universal testing among all pregnant patients at the time of admission for SARS-CoV-2, the virus that causes COVID-19.

15 Aug 2020

COVID-19 crisis could offer valuable insights for climate change mitigation efforts

The dynamics of the current COVID-19 pandemic could offer valuable insights for the efforts to mitigate climate change.

15 Aug 2020

Poor hygiene and antibiotic use can contribute to colonization of antimicrobial-resistant bacteria

Scientists have found clear indicators for how the interaction of poor hygiene and antibiotic use contribute to the colonization of antimicrobial-resistant (AMR) bacteria in humans, a problem that contributes to hundreds of thousands of deaths annually.

15 Aug 2020

New discoveries could change the understanding and treatment of ovarian cancer

Recent discoveries made by researchers at Texas A&M University could change the way ovarian cancer is understood and treated.

15 Aug 2020

Frequently used serology test may not detect SARS-CoV-2 antibodies, shows study

Two different types of detectable antibody responses in SARS-CoV-2 (COVID-19) tell very different stories and may indicate ways to enhance public health efforts against the disease, according to researchers at The University of Texas MD Anderson Cancer Center.

15 Aug 2020

Nanoparticle carriers expand the effectiveness of gene therapies for human eye diseases

NIBIB-funded researchers have created nanoparticles for successful gene therapy of a mouse model of macular degeneration.

15 Aug 2020

Gaiter face covering provides respiratory containment of exhaled droplets

Experts with the West Virginia University Center for Inhalation Toxicology found that – assuming it's a good fit - a gaiter will, despite recent reports, provide a respiratory containment of exhaled droplets comparable to a common over-the-ear cloth mask.

15 Aug 2020

Pregnant mother's immune conditions linked to behavioral, emotional problems in children with autism

Children with autism born to mothers who had immune conditions during their pregnancy are more likely to have behavioral and emotional problems, a UC Davis Health study has found.

15 Aug 2020

Influenza-virus-based vaccine platform another viable option against SARS-CoV-2

In a novel proof of concept study, published on the bioRxiv preprint server, U.S. researchers used attenuated influenza viral particles that express severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor-binding domain to induce neutralizing antibodies in mice – unveiling another viable vaccine candidate for preventing coronavirus disease (COVID-19).

14 Aug 2020

Medical Research News

Study shows nitrate supplementation improves diaphragm's function in elderly people

Coronacept - A trap-and-destroy molecule against SARS-CoV-2

Targeting SARS-CoV-2 with off-the-shelf CAR-NK cells

Potential inhibitors of SARS-CoV-2 identified

ARDS may not be the primary lung iInjury in COVID-19

Scientists reveal most likely order of COVID-19 symptoms

U.S. scientists to create coronavirus strain for human challenge trials

SARS-CoV-2 spike pocket is a putative target for antiviral design

Multiphase program provides valuable lessons for advancing the fight against malaria

New study challenges hypothesis underlying the sensitivity of mammalian auditory system

Historical redlining associated with adverse birth outcomes

Number of in-person health care visits not linked to COVID-19 infection in pregnant patients

COVID-19 crisis could offer valuable insights for climate change mitigation efforts

Poor hygiene and antibiotic use can contribute to colonization of antimicrobial-resistant bacteria

New discoveries could change the understanding and treatment of ovarian cancer

Frequently used serology test may not detect SARS-CoV-2 antibodies, shows study

Nanoparticle carriers expand the effectiveness of gene therapies for human eye diseases

Gaiter face covering provides respiratory containment of exhaled droplets

Pregnant mother's immune conditions linked to behavioral, emotional problems in children with autism

Influenza-virus-based vaccine platform another viable option against SARS-CoV-2

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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