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Brown researchers receive federal grant to track adverse impacts of vaccines in elderly residents

As the U.S. moves toward the highly anticipated approval of the first COVID-19 vaccines, residents of nursing homes and other long-term care facilities are likely to join health care workers as groups who will be among the earliest vaccine recipients in most states.

2 Dec 2020

Personality growth in young adulthood provides real-world career benefits

Data analysis of a 12-year longitudinal study examining the importance of personality changes during young adulthood indicates personality growth has real-world career benefits.

2 Dec 2020

SARS-CoV-2 D614G mutation does not affect performance of serological assays

In a new study published in The Journal of Infectious Diseases, US researchers considered the emergence of a new SARS-CoV-2 spike protein variant. They compared spike G614-based assay to the original D614-based assay – pointing towards the development of recognizable, cross-responsive humoral immunity.

2 Dec 2020

Infants show high night-to-night variability in sleeping patterns

New parents often expect their baby to start sleeping through the night around the time they reach six months of age.

2 Dec 2020

Automated AI measurement of abdominal fat predicts major cardiovascular events

Automated deep learning analysis of abdominal CT images produces a more precise measurement of body composition and predicts major cardiovascular events, such as heart attack and stroke, better than overall weight or body mass index (BMI), according to a study presented today at the annual meeting of the Radiological Society of North America.

2 Dec 2020

COVID-19-related disruptions to cervical cancer screening could increase risk sevenfold, UK case study finds

A new study reveals inequalities in the delay in screening for cervical cancer, and recommends that the screening capacity be increased in addition to giving a higher priority to women who have missed their scheduled visit.

2 Dec 2020

Modeling study predicts 90 percent drop in COVID-19 deaths following vaccination in US

A new modeling study of the United States suggests that vaccination could markedly reduce the rate of infection, hospitalizations and mortality in the current COVID-19 pandemic – even if confined to adults alone.

2 Dec 2020

Data modeling study assesses effectiveness of NPIs in reducing COVID-19 reproduction number worldwide

As a second wave of the COVID-19 pandemic hits many regions worldwide, a new study reports a method to monitor the effective reproduction number (Re) in near real-time.

2 Dec 2020

Spanish-originated SARS-CoV-2 variant A222V shows rapid spread in Lazio, Italy

A startling new study reports the rapid rise to dominance of a new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strain in Italy. This strain, termed the GV clade, is characterized by a single point mutation.

2 Dec 2020

UTHSC receives $1.25 million to conduct a study on improving adherence to HPV vaccine

The human papillomavirus (HPV) vaccine was introduced in the United States for preteens more than a dozen years ago, yet adherence rates are still below those for other childhood vaccines.

2 Dec 2020

A new potential COVID-19 vaccine candidate: YF-S0

A recent study published in the journal Nature describes the safety and efficacy of a live-attenuated yellow fever 17D (YF17D) vector-based vaccine candidate expressing a non-cleavable form of the spike protein of severe acute respiratory coronavirus 2 (SARS-CoV2).

2 Dec 2020

New and sudden headaches may be a symptom of COVID-19

Researchers report a case of a young male patient who came in with a headache to an emergency room. He had increased intracranial pressure and tested positive for SARS-CoV-2, suggesting new headaches during the pandemic should not be ignored.

2 Dec 2020

Scientists detect a sarbecovirus phylogenetically related to SARS-CoV-2 from bats in Japan

A team of researchers at the University of Tokyo in Japan have detected a sarbecovirus, called Rc-o319, which is phylogenetically positioned in the same clade as SARS-CoV-2 in Rhinolophus cornutus bats in Japan.

2 Dec 2020

Drinking obstructs a chemical that boosts attention

In a new paper, researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) report brain chemistry that may contribute to why drinkers have difficulty paying attention while under the influence.

2 Dec 2020

Particulate matter levels can play a significant role in SARS-CoV-2 transmission

A new study has found that particulate matter (PM) plays a role in providing surfaces for SARS-CoV-2 transmission and interaction, enabling fomite transmission through deposition.

2 Dec 2020

SARS-CoV-2 deletion mutations may have attenuated infectivity in some strains

A team of researchers at the University of Hong Kong has identified a panel of SARS-CoV-2 variants, called Del-mut, which contains a deletion in the S1/S2 junction. Upon investigating one of the deleted variants in animal models, they found that Del-mut-1 is attenuated in its ability to cause disease or pathological changes.

2 Dec 2020

Study finds 10 metabolites associated with risk of stroke

Results from a new study are published in Neurology®, which identifies 10 metabolites that are associated with a person’s risk of stroke.

2 Dec 2020

Study: Maternal omega-3 deficiency can alter the development of neuronal networks in offspring

Omega-3 fatty acids are essential, necessarily supplied by the diet and indispensable to brain development.

2 Dec 2020

Genethon to start international clinical trial for treatment of Duchenne muscular dystrophy

Genethon, dedicated to designing and developing gene therapy products for rare diseases, received this Monday 30th of November the authorization from the ANSM, the French National Agency for Medicines and Health Products Safety, to start in France a multicentre international clinical trial for the treatment of Duchenne muscular dystrophy with product GNT 004.

2 Dec 2020

Researchers develop first report card on biosimilars for three blockbuster cancer drugs

Researchers have developed the first report card on biosimilars for three blockbuster cancer drugs marketed by Genentech/Roche: Rituxan, Avastin, and Herceptin.

2 Dec 2020

Medical Research News

Brown researchers receive federal grant to track adverse impacts of vaccines in elderly residents

Personality growth in young adulthood provides real-world career benefits

SARS-CoV-2 D614G mutation does not affect performance of serological assays

Infants show high night-to-night variability in sleeping patterns

Automated AI measurement of abdominal fat predicts major cardiovascular events

COVID-19-related disruptions to cervical cancer screening could increase risk sevenfold, UK case study finds

Modeling study predicts 90 percent drop in COVID-19 deaths following vaccination in US

Data modeling study assesses effectiveness of NPIs in reducing COVID-19 reproduction number worldwide

Spanish-originated SARS-CoV-2 variant A222V shows rapid spread in Lazio, Italy

UTHSC receives $1.25 million to conduct a study on improving adherence to HPV vaccine

A new potential COVID-19 vaccine candidate: YF-S0

New and sudden headaches may be a symptom of COVID-19

Scientists detect a sarbecovirus phylogenetically related to SARS-CoV-2 from bats in Japan

Drinking obstructs a chemical that boosts attention

Particulate matter levels can play a significant role in SARS-CoV-2 transmission

SARS-CoV-2 deletion mutations may have attenuated infectivity in some strains

Study finds 10 metabolites associated with risk of stroke

Study: Maternal omega-3 deficiency can alter the development of neuronal networks in offspring

Genethon to start international clinical trial for treatment of Duchenne muscular dystrophy

Researchers develop first report card on biosimilars for three blockbuster cancer drugs

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

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