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Direct oral anticoagulant does not appear to offer protection against severe COVID-19

DOAC (direct oral anticoagulant) pills are used in the treatment of atrial fibrillation by preventing blood clots. Even though blood clots are thought to contribute to complications from the new coronavirus infection, users of this class of drug do not seem to be protected against severe COVID-19, reports a large Swedish registry study from Karolinska Institutet published in The Journal of Internal Medicine.

1 Dec 2020

SARS-CoV-2's microRNAs may have promoted its jump to humans

A new study uses machine learning to explore the small microRNAs (or miRNAs) of SARS-CoV-2 that may determine the virus's ability to successfully infect humans by altering the course of transcriptional events.

1 Dec 2020

Chinese woman still sheds SARS-CoV-2 over four months post-infection

A new study by Chinese scientists explore an unusual case of extended viral shedding in a 68-year-old woman up to four months post-infection.

1 Dec 2020

COVID-19 restrictions have led to 86 percent drop in norovirus infections in US, finds study

The onset of the COVID-19 pandemic led to the imposition of several non-pharmaceutical interventions (NPIs) across the world. While citizens in the USA have been chafing over the advice to wear masks in public, restricted social interactions, and limited attendance at schools, colleges and workplaces, a new study published on the preprint server medRxiv* in November 2020 reports that these NPIs were linked to a steep reduction in the incidence of the non-respiratory pathogen, noroviruses.

1 Dec 2020

Low endorsement among doctors worldwide for COVID-19 ‘immunity passports’

A cross-sectional survey conducted in September 2020, aimed at assessing the views of a randomly selected, stratified physician sample on this matter, drawing names from physicians registered with the global networking platform called Sermo. This offers its registration service to verified licensed physicians.

1 Dec 2020

New innovation could restore sight to the blind

Researchers have made significant steps towards developing a brain implant that will restore sight to those affected by visa impairment and blindness.

1 Dec 2020

Experimental stem cell gene therapy may give a new lease of life for patient with sickle cell disease

"But it's a marathon whereas you keep going, the trail gets rockier and then you lose your shoes," the 27-year-old said. "It gets harder as you get older. Things start to fail and all you can think about is how much worse it's going to get down the road."

1 Dec 2020

Multiple pregnancies may affect the body's physical aging process

Having children doesn't just make you feel like you've aged overnight -- a new study led by Penn State researchers found that the number of times a person gives birth may also affect the body's physical aging process.

1 Dec 2020

Gut microbiota directly shapes the makeup of human immune system, shows study

MSK researchers have uncovered an important finding about the relationship between the microbiota and the immune system, showing for the first time that the concentration of different types of immune cells in the blood changes in relation to the presence of different bacterial strains in the gut.

1 Dec 2020

New combination technique separates cell types, may prove effective against pathogens

To develop effective therapeutics against pathogens, scientists need to first uncover how they attack host cells. An efficient way to conduct these investigations on an extensive scale is through high-speed screening tests called assays.

1 Dec 2020

Chloroquine/hydroxychloroquine could treat COVID-19 infection

The recent serious outbreak of Covid19 has affected (November 13, 2020) 53,796,098 people worldwide, resulting in 37,555,669 recovered, 1,310,250 deaths, and a large number of open cases.

1 Dec 2020

Inpatient consultation service could reduce health care costs, hospital admissions in pediatric intensive care

When medically complex children are hospitalized, linking hospitalists to their regular outpatient providers through an inpatient consultation service were more likely to improve outcomes, according to researchers at The University of Texas Health Science Center at Houston (UTHealth).

1 Dec 2020

Studies show that age bias varies among countries and even states

Elders are more respected in Japan and China and not so much in more individualistic nations like the United States and Germany, say Michigan State University researchers who conclude in a pair of studies that age bias varies among countries and even states.

1 Dec 2020

Researchers successfully edit SIV virus from genomes of non-human primates

Taking a major step forward in HIV research, scientists at the Lewis Katz School of Medicine at Temple University have successfully edited SIV - a virus closely related to HIV, the cause of AIDS - from the genomes of non-human primates.

1 Dec 2020

Study demonstrates safety of novel immuno-oncology therapy in patients with advanced solid tumors

A novel therapy designed to help stimulate the body's immune system response against cancer appears to be safe to use as alone or in combination with immune checkpoint inhibitors.

1 Dec 2020

Study shows critically ill patients are not seeking care for fear of COVID-19 infection

During the early days of the COVID-19 pandemic in New England, emergency department visits for medical emergencies - including psychiatric problems, trauma and heart attacks - declined by nearly a third, raising concerns among clinicians that critically ill patients were not seeking the care they needed for fear of coronavirus infection.

1 Dec 2020

Analysis of social media messages reveals struggles of care home staff during COVID-19 first wave

Analysis of social media messages between care home staff on the coronavirus front line reveal their growing concerns over how to manage in the face of the virus. Thousands of Whatsapp messages between 250 care home workers during the first coronavirus wave show workers were often asking questions which went unanswered due to a lack of proper guidance.

1 Dec 2020

Researchers assess how social factors can influence pain responses

We take for granted the fact that feelings such as love, happiness, or pain are described with different words and expressions across languages. But are these differences in the ways we express these feelings in different languages also tied to differences in the sensations themselves?

1 Dec 2020

Doctors report first case of mirror writing in patient with epilepsy

In new research presented at Euroanaesthesia (the annual meeting of the European Society of Anaesthesiology and Intensive Care [ESAIC]), doctors report a highly unusual case of a right-handed patient performing unconscious 'mirror-writing' with her left hand while in the midst of having epileptic seizures in the emergency room.

1 Dec 2020

MIT study shows how the brain is wired for reactive, reflexive movements

When riding your bike to the store you might have two very different reasons to steer: plain old reflex when you something dart into your path, or executive control when you see street signs that indicate the correct route.

1 Dec 2020

Medical Research News

Direct oral anticoagulant does not appear to offer protection against severe COVID-19

SARS-CoV-2's microRNAs may have promoted its jump to humans

Chinese woman still sheds SARS-CoV-2 over four months post-infection

COVID-19 restrictions have led to 86 percent drop in norovirus infections in US, finds study

Low endorsement among doctors worldwide for COVID-19 ‘immunity passports’

New innovation could restore sight to the blind

Experimental stem cell gene therapy may give a new lease of life for patient with sickle cell disease

Multiple pregnancies may affect the body's physical aging process

Gut microbiota directly shapes the makeup of human immune system, shows study

New combination technique separates cell types, may prove effective against pathogens

Chloroquine/hydroxychloroquine could treat COVID-19 infection

Inpatient consultation service could reduce health care costs, hospital admissions in pediatric intensive care

Studies show that age bias varies among countries and even states

Researchers successfully edit SIV virus from genomes of non-human primates

Study demonstrates safety of novel immuno-oncology therapy in patients with advanced solid tumors

Study shows critically ill patients are not seeking care for fear of COVID-19 infection

Analysis of social media messages reveals struggles of care home staff during COVID-19 first wave

Researchers assess how social factors can influence pain responses

Doctors report first case of mirror writing in patient with epilepsy

MIT study shows how the brain is wired for reactive, reflexive movements

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

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