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Women with unexplained miscarriages have altered perceptions to male body odors

Women who have suffered unexplained repeated pregnancy loss (uRPL) have altered perceptions and brain responses to male body odors, in comparison to those with no history of uRPL, suggests a new study published today in eLife.

30 Sep 2020

A TLR2 agonist reduces SARS-CoV-2 in upper respiratory tract of ferret model

In a recent bioRxiv* preprint paper, Professor Miles W. Carroll et al. study an agonist for reducing the SARS-CoV-2's viral load. They show that prophylactic intra-nasal administration of TLR2/6 (toll-like receptor) agonist, INNA-051, reduces viral RNA in the nose and throat, in a ferret model.

30 Sep 2020

Oral antibiotics are effective for treating cystic fibrosis, shows new clinical trial

A major national study led by experts from Bristol and Nottingham has found that oral antibiotics are just as effective as intravenous antibiotics in killing a common germ that causes dangerous complications in cystic fibrosis (CF) patients.

30 Sep 2020

Different triggers for Kawasaki disease suggest slightly different genetic susceptibilities

Researchers at University of California San Diego report that while Kawasaki disease (KD) occurs in clusters, the traits, and thus the triggers of the inflammatory disease vary among clusters. The findings are published in the September 2020 online issue of The Journal of Pediatrics.

30 Sep 2020

Researchers develop research model to understand the impact of coronavirus on lungs

Scientists at Boston University's National Emerging Infectious Diseases Laboratories (NEIDL) and the Center for Regenerative Medicine (CReM) joined forces to develop the most relevant research model possible for understanding how the coronavirus virus impacts the lungs, by engineering living, "breathing" human lung cells from stem cells for the task.

30 Sep 2020

Researchers identify a new method to produce miniaturized antibodies

Researchers at the University of Bath in the UK and biopharma company UCB have found a way to produce miniaturized antibodies, opening the way for a potential new class of treatments for diseases.

30 Sep 2020

Study shows how Cisplatin chemotherapy leads to neuronal apoptosis

Despite the great advances in cancer research in recent years, treatments that can cause very severe adverse effects are still used. This is the case of neuropathy caused by chemotherapy with platinum derivatives, such as Cisplatin and Oxaliplatin.

30 Sep 2020

Gut bacteria may play a role in prostate cancer therapies

A new study from Lawson Health Research Institute and Western University illustrates how the gut microbiome interacts with an oral medication in prostate cancer patients, suggesting bacteria in the gut play a role in treatment outcomes.

30 Sep 2020

First pathoconnectome shows how eye disease alters retinal circuitry

Scientists from the John A. Moran Eye Center at the University of Utah have achieved another first in the field of connectomics, which studies the synaptic connections between neurons.

30 Sep 2020

Exosomes yield regenerative benefits equivalent to hiPSC-CCs, shows study

Science has long known that recovery from experimental heart attacks is improved by injection of a mixture of heart muscle cells, endothelial cells and smooth muscle cells, yet results have been limited by poor engraftment and retention, and researchers worry about potential tumorigenesis and heart arrhythmia.

30 Sep 2020

Study shows tofacitinib drug can repair permeability defects in the intestine

A team of researchers led by biomedical scientist Declan F. McCole at the University of California, Riverside, has found that the drug tofacitinib, also called Xeljanz and approved by the FDA to treat rheumatoid arthritis and ulcerative colitis, can repair permeability defects in the intestine.

30 Sep 2020

Small for gestational age babies more likely to experience asymmetric growth

Carrying a fetus that is small for gestational age is associated with increased rates of stillbirth and neonatal death as well as metabolic disease in later life.

30 Sep 2020

Scientists identify mutations in single genes linked to certain cases of cerebral palsy

The causes of cerebral palsy have long been debated and often are attributed to in utero infections, premature birth, or brain injury to the baby near or during delivery, usually from a lack of oxygen.

30 Sep 2020

Research can help better manage body temperature regulation and hydration in older adults

Our ability to regulate body temperature and keep our bodies from becoming dehydrated declines as we get older. New research published today in The Journal of Physiology improves our understanding of the relation between temperature regulation and dehydration.

30 Sep 2020

Simple interactions between nerve cells can shape complex brain circuits

Complex brain circuits in rodents can organize themselves with genetics playing only a secondary role, according to a new computer modelling study published today in eLife.

30 Sep 2020

Blocking the self-destruction process of enzymes can mitigate age-related diseases

Stopping the cannibalistic behavior of a well-studied enzyme could be the key to new drugs to fight age-related diseases, according to a new study published online in Nature Cell Biology.

30 Sep 2020

Genetic testing can identify 'concealed cardiomyopathies' in sudden cardiac arrest survivors

Centenary Institute researchers have discovered that genetic testing can identify ‘concealed cardiomyopathies’ in nearly a quarter of sudden cardiac arrest survivors who seem to have a normal heart.

30 Sep 2020

Sleep apnea increases risk of severe COVID 19

Coronavirus disease (COVID-19) is a respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. A subset of COVID-19 patients face a severe form of the disease with hospitalization, respiratory failure, or death. Severe COVID-19 is primarily characterized by respiratory distress, and the common risk factors are older age, obesity, cardiovascular disease, diabetes, and poor lung function.

29 Sep 2020

College football crowds could impact COVID-19 spread

The observed increase in COVID-19 cases coinciding with the reopening of college campuses all over the US has drawn intense scientific attention. A recent paper, by Washington State University researchers, published on the preprint server medRxiv* in September 2020 reports that this threat is directly linked to the holding of in-person sporting events on these campuses.

29 Sep 2020

New graphical tool to identify potent neutralizing antibodies against SARS-CoV-2

A new study by researchers at the Indian Institute of Science and the University of Queensland and published on the preprint server medRxiv in September 2020 discusses using a novel tool to identify the most effective among currently known anti-SARS-CoV-2 NAbs.

29 Sep 2020

Medical Research News

Women with unexplained miscarriages have altered perceptions to male body odors

A TLR2 agonist reduces SARS-CoV-2 in upper respiratory tract of ferret model

Oral antibiotics are effective for treating cystic fibrosis, shows new clinical trial

Different triggers for Kawasaki disease suggest slightly different genetic susceptibilities

Researchers develop research model to understand the impact of coronavirus on lungs

Researchers identify a new method to produce miniaturized antibodies

Study shows how Cisplatin chemotherapy leads to neuronal apoptosis

Gut bacteria may play a role in prostate cancer therapies

First pathoconnectome shows how eye disease alters retinal circuitry

Exosomes yield regenerative benefits equivalent to hiPSC-CCs, shows study

Study shows tofacitinib drug can repair permeability defects in the intestine

Small for gestational age babies more likely to experience asymmetric growth

Scientists identify mutations in single genes linked to certain cases of cerebral palsy

Research can help better manage body temperature regulation and hydration in older adults

Simple interactions between nerve cells can shape complex brain circuits

Blocking the self-destruction process of enzymes can mitigate age-related diseases

Genetic testing can identify 'concealed cardiomyopathies' in sudden cardiac arrest survivors

Sleep apnea increases risk of severe COVID 19

College football crowds could impact COVID-19 spread

New graphical tool to identify potent neutralizing antibodies against SARS-CoV-2

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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