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Study of glycosylation on SARS-CoV-2 spike protein

The first intimation of the current COVID-19 crisis came with the news of severe pneumonic illness caused by an unknown agent in a Chinese city called Wuhan, issued on the last day of 2019. Following this, researchers found the cause to be a novel coronavirus, closely related to the earlier SARS virus, now called severe acute respiratory syndrome coronavirus 2.

8 Jul 2020

Analysis across 170 countries of Government responses to COVID-19

An exciting new study by researchers at the Universities of Oxford and Edinburgh and published on the preprint server medRxiv* in July 2020 reports that early and stringent government measures in the form of non-pharmaceutical interventions (NPIs) against the spread of COVID-19 results in a significant reduction in the mortality due to this disease. The finding could help shape public health policies in the absence of effective vaccines or therapeutic drugs.

8 Jul 2020

Asthma inhalers being trialed for treatment of COVID-19

Researchers from Queensland University of Technology and Oxford University are working in collaboration to begin human clinical trials of inhaled corticosteroids, commonly used for asthma patients, on patients with COVID-19. The researchers believe that this could be useful for patients with the novel coronavirus infection.

7 Jul 2020

Research shows probiotics can help combat anxiety and depression

Previous research has tied mental health issues and developmental disorders to gut health. Now, a team of British scientists has shown that foods that broaden the profile of helpful bacteria in the gut, which are collectively known as probiotics, can help ease anxiety and depression.

7 Jul 2020

Many in the UK would refuse a coronavirus vaccine, survey finds

The novel coronavirus pandemic (COVID-19) has left many scientists and pharmaceutical companies racing to develop an effective vaccine to combat the viral infection. With 21 candidate vaccines in clinical evaluation, 139 candidate vaccines in preclinical evaluation across the world, most countries are hoping to be first to the post.

7 Jul 2020

New studies examine outcomes of kidney transplant recipients with COVID-19

Two new studies examine the health and outcomes of patients with COVID-19 who have undergone kidney transplantation or are receiving hemodialysis. The findings appear in an upcoming issue of CJASN.

7 Jul 2020

Study finds staggering inaccuracy in Medicare beneficiaries' race and ethnicity data

The information critical to a nationwide priority of reducing health care disparities among minorities is incomplete and inaccurate, according to a new Rutgers study.

7 Jul 2020

BUSPH study outlines how remdesivir could save lives in countries with less hospital capacity

Amid news that the United States has bought up virtually the entire global supply of remdesivir, a new Boston University School of Public Health (BUSPH) study outlines how the drug could save lives in countries with less hospital capacity, such as South Africa, where COVID-19 is beginning to overwhelm intensive care units (ICUs).

7 Jul 2020

Research sheds light on mysterious COVID-19 related hyperinflammatory shock in children

The ongoing COVID-19 pandemic has cost hundreds of thousands of human lives, besides more than 11 million cases. Caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the disease was initially thought to be more severe in the elderly and those with pre-existing medical conditions. However, it started to manifest in children after the peak of the first wave.

7 Jul 2020

How facemasks protect against COVID-19

The “new normal” is a way of living that helps prevent contracting the novel coronavirus. These include practices such as wearing masks in public places and staying at least six feet from each other. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes the coronavirus disease (COVID-19), can be transmitted via respiratory droplets when a person sneezes, coughs, or talks.

7 Jul 2020

Coronavirus study shows herd immunity is infeasible

Herd immunity has been one of the key topics amid the coronavirus pandemic. Previous reports show that when a large proportion of the population gets immune to the novel coronavirus, through vaccination, herd immunity can be achieved.

7 Jul 2020

Aspirin and flavonoids in fruits and vegetables could help prevent colorectal cancer

A diet rich in fruits and vegetables and a daily dose of aspirin have one thing in common - both can help prevent colorectal cancer. Yet scientists have struggled for decades to find the source of their ability to inhibit cancer cell growth.

7 Jul 2020

Scientists receive grant to study cerebrovascular changes during healthy and Alzheimer's aging

Scientists often focus on abnormal accumulations of proteins called plaques in the brain in efforts to find a treatment for Alzheimer's disease. But the effects of these plaques have not been clear.

7 Jul 2020

Risk of severe COVID-19 in ~50 kb genomic segment inherited from Neanderthals

Researchers have found that a small fragment of the genetic code that has been inherited by modern humans from Neanderthals could carry the secret of why some people succumb to a severe form of COVID-19 requiring hospitalization, while others recover.

7 Jul 2020

Study explores the role of gut Piezo1 in sensing of bacterial RNA

In a new study published in Cell, "RNA sensing by gut Piezo1 is essential for systemic serotonin synthesis", a research team led by Kenta Maruyama M.D., Ph.D. from National Institute for Physiological Sciences explored the role of Piezo1, a mechano-sensing receptor, in the sensing of bacterial RNA.

7 Jul 2020

Researchers develop bioprinted skin model of cutaneous squamous cell carcinoma

The cover for issue 27 of Oncotarget features "Bimodal imaging examples of control and treated tumors (red) before and after the treatment period," by Browning, et al. and reported that the authors developed a 3-dimensional bioprinted skin model of cutaneous squamous cell carcinoma (cSCC) tumors together with a microscopy assay to test chemotherapeutic effects in tissue.

7 Jul 2020

Gene expression networks flag potential therapeutic targets for SARS-CoV-2

An international team of researchers from Canada, Australia, the Netherlands, and the United States has identified dozens of genes that could contribute to the pathology of coronavirus disease 2019 (COVID-19) and serve as potential therapeutic targets.

7 Jul 2020