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Breast cancer cells can reprogram natural killer cells to aid in metastasis

Natural killer cells, a type of immune cell, are known to limit metastasis by inducing the death of cancer cells. But metastases still form in patients, so there must be ways for cancer cells to escape.

9 Jul 2020

Groundbreaking study identifies unique lung cells that may drive pulmonary fibrosis

A groundbreaking study published today and led by the Translational Genomics Research Institute, an affiliate of City of Hope, identifies unique lung cells that may drive Idiopathic Pulmonary Fibrosis, a deadly lung disease that affects hundreds of thousands of Americans, and for which there is no cure.

9 Jul 2020

Researchers identify factor that regulates the abnormal growth of heart

The human heart is like a sponge, able to expand and grow, increasing its capacity to take up blood. In theory, an enlarged heart can also squeeze out more blood, with more power, than an average-sized heart. But in reality, for most people, this growth - known as cardiac hypertrophy - is abnormal and signals trouble.

9 Jul 2020

Study examines the long-term impacts of child abuse

In a new study published in the leading international journal, Child Abuse and Neglect, University of South Australia researchers have found that by their mid-teens, children who were the subject of child protective services contact, are up to 52 percent more likely to be hospitalized, for a range of problems, the most frequent being mental illness, toxic effects of drugs and physical injuries.

9 Jul 2020

Research shows Black individuals are twice as likely to test positive for COVID-19

Results of an analysis published in the Annals of the American Thoracic Society found that Black individuals were twice as likely as White individuals to test positive for COVID-19.

9 Jul 2020

Increase in blood sodium levels influences the biological clock of mice

A new study from McGill University shows that increases in the concentrations of blood sodium can have an influence on the biological clock of mice, opening new research avenues for potentially treating the negative effects associated with long distance travel or shift work.

9 Jul 2020

Study shows optimistic people sleep better and live longer

Optimists live longer than pessimists and have a lower risk of chronic disease - this has been scientifically validated on multiple occasions.

9 Jul 2020

New nanoconjugate blocks dissemination of tumor cells in animal models of acute myeloid leukemia

The nanoparticle targets only leukemic cells and therefore would reduce the severe adverse effects of current treatments.

9 Jul 2020

People with arthritis report worsening symptoms during Covid-19 lockdown

People with arthritis experienced a ‘roller coaster’ of emotions and saw their symptoms worsen during the Covid-19 lockdown – according to research from the University of East Anglia.

9 Jul 2020

UniSA researchers pioneer new method to more accurately diagnose Parkinson’s disease

University of South Australia researchers are pioneering a new method to more accurately diagnose Parkinson’s disease, a neurodegenerative brain disorder which affects around 70,000 Australians, resulting in a loss of control of body movements.

9 Jul 2020

Cloth face coverings, masks are effective in reducing the spread of COVID-19, study says

Cloth face coverings, even homemade masks made with the correct material, are effective in reducing the spread of COVID-19 - for the wearer and those around them - according to a new study published today from Oxford’s Leverhulme Centre for Demographic Science.

9 Jul 2020

siRNA therapeutics can reduce off-target side effects of anticancer drugs

Small interfering RNA (siRNA) has shown tremendous potential for treating human diseases in the past decades.

9 Jul 2020

PRMT5 inhibitors can help treat advanced melanoma

Scientists at Sanford Burnham Prebys Medical Discovery Institute have demonstrated the therapeutic potential of PRMT5 inhibitors to sensitize unresponsive melanoma to immune checkpoint therapy.

9 Jul 2020

New research shows promise for treating neuropsychiatric diseases

When trying to complete a task we are constantly bombarded by distracting stimuli. How does the brain filter out these distractions and enable us to focus on the task at hand?

9 Jul 2020

Ozone gas can provide a safe means to disinfect personal protective equipment

A new study shows that ozone gas, a highly reactive chemical composed of three oxygen atoms, could provide a safe means for disinfecting certain types of personal protective equipment that are in high demand for shielding health care personnel from Covid-19.

9 Jul 2020

Research shows how SARS-CoV-2 alters translation

Now, a new study published on the preprint server bioRxiv in July 2020 shows that the 5’ end of the RNA molecule is capable of inhibiting the binding of mRNA to the ribosomal 40S subunit, thus preventing translation.

9 Jul 2020

Researchers map RNA structure throughout SARS-CoV-2 genome

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which is currently at the heart of a pandemic that has cost the world more than 550,000 lives, 12 million infections, and uncounted years of productivity, is an RNA virus with the largest genome among all such viruses. This 30 kb size virus has caused many difficulties for scientists in search of a vaccine.

9 Jul 2020

New method helps pinpoint new potential therapeutic targets for lupus

A team of researchers from Children's Hospital of Philadelphia (CHOP) used a new method of pinpointing potential disease-causing changes in the genome to identify two new potential therapeutic targets for lupus, while also paving the way for more accurately identifying disease-causing variations in other autoimmune disorders.

8 Jul 2020

Tracing adaptation to ACE2 use in sarbecoviruses

A detailed study published on the preprint server bioRxiv in July 2020 argues that recombination accounts for the appearance of the ability of both SARS-CoV and SARS-CoV-2 to use the human angiotensin-converting enzyme (hACE) 2 as the binding receptor mediating viral infection of human cells.

8 Jul 2020

Community development initiative reduced rates of high-cost care, study finds

More than a decade into the community development initiative called Healthy Neighborhoods Healthy Families, the 30-block Southern Orchards neighborhood on Columbus, Ohio's South Side had clear, notable improvement. Home vacancy fell from 30% to under 6%.

8 Jul 2020