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Decision conflict may lead to less favorable treatment outcomes in cancer patients

Nearly one-third of cancer patients who decide to undergo surgery for their condition may have second thoughts, and this decision conflict may lead to less favorable treatment outcomes in both the near- and long-term, according to a team of investigators at Massachusetts General Hospital (MGH) and Ariadne Labs, a joint center for health systems innovation at the Harvard T.H. Chan School of Public Health and Brigham and Women's Hospital (BWH).

30 Oct 2020

Study reveals molecular mechanism that increases the invasiveness of radioresistant cancer cells

Scientists have revealed the molecular mechanism regulating the trafficking of lysosomes that increases the invasiveness of radioresistant cancer cells following radiotherapy.

30 Oct 2020

Children with multiple islet autoantibodies are more likely to progress to type 1 diabetes

Children with multiple islet autoantibodies - biological markers of autoimmunity -- are more likely to progress to symptomatic type 1 diabetes (T1D) than those who remain positive for a single autoantibody.

30 Oct 2020

Study examines link between SARS-CoV-2 genomic load and COVID-19 patient outcomes

A new study published online in the Annals of the American Thoracic Society examines whether the amount of RNA, or genomic load, of SARS-CoV-2 detected in swab tests of patients being admitted to the hospital with viral pneumonia is associated with more severe COVID-19.

30 Oct 2020

Addictive drug displays different acute pharmacology and synaptic plasticity

Nucleus accumbens in the brain play a central role in the risk-reward circuit. Their operation is based chiefly on three essential neurotransmitters: dopamine, which promotes desire; serotonin, whose effects include satiety and inhibition; and glutamate, which drives goal-directed behaviors and responses to reward-associated cues and contexts.

30 Oct 2020

SARS-CoV-2 spike proteins can directly impact the blood-brain barrier

Like a key, SARS-CoV-2 - the virus that causes coronavirus disease 2019 (COVID-19) - attaches to specific molecules on the host cell surface, opening gateways into the cell interior.

30 Oct 2020

Novel approach can help measure antibodies against SARS-CoV-2

A new study lead by Helmholtz Zentrum München indicates a six-fold higher SARS-CoV-2 exposure rate among children in Bavaria, Germany, than reported cases.

30 Oct 2020

Research shows some COVID-19 patients experience long-lasting skin symptoms

Some COVID-19 patients experience long-lasting skin symptoms that vary according to type of COVID-19 skin rash, a late-breaking abstract will reveal today at the 29th EADV Congress, EADV Virtual.

30 Oct 2020

Study shows statins can have adverse effects on certain organs

600,000 Danes take medicine containing statins. Statins lower the cholesterol level and thus helps prevent cardiovascular disease and blood clots.

30 Oct 2020

Researchers identify distinct link between autism and brain cell abnormalities

Johns Hopkins Medicine researchers report that new experiments with genetically engineered mice have found clear connections among a range of autism types and abnormalities in brain cells whose chemical output forges platonic (non-sexual) feelings of love and sociability.

30 Oct 2020

Scientists develop new model of coronavirus diffusion through a community

The coronavirus doesn't spread uniformly through a community.But in the world of disease modeling, many projections take a high-level approach to a geographic area, like a county or state, and forecast based on a general idea that a virus will take root and spread at an equal rate until it reaches its peak of infection.

30 Oct 2020

Study: ICE detention centers experienced repeated outbreaks of vaccine-preventable illnesses

More than a dozen U.S. Immigration and Customs Enforcement (ICE) detention centers experienced large, repeated outbreaks of vaccine-preventable illnesses in the last three years, according to a new study by researchers at UC San Francisco.

30 Oct 2020

Study: Toxins produced by tube-dwelling anemones have pharmacological potential

Researchers based in Brazil and the United States have completed the first-ever mapping exercise to profile the toxins produced by tube-dwelling anemones, or cerianthids, a family of marine animals belonging to the same phylum (Cnidaria) as sea anemones, jellyfish and corals.

30 Oct 2020

Penn State and Stanford University collaborate to develop two-hour sepsis test

One in three people who die in U.S. hospitals have sepsis, the body's extreme response to infection that can lead to multiple organ failure. Diagnosis can take up to five days, but death may take only hours from the initial onset of sepsis.

30 Oct 2020

RNI researchers to study the impact of excessive speeds on the human brain, body

Before the first Virgin Hyperloop ride takes off, the brains behind pioneering neuroscience research at West Virginia University will help ensure the health and well-being of its passengers and operators.

30 Oct 2020

COVID-19-related myocarditis may be a relatively rare occurrence, indicates study

A study conducted by Richard Vander Heide, MD, PhD, Professor and Director of Pathology Research at LSU Health New Orleans School of Medicine, and Marc Halushka, MD, PhD, Professor of Pathology at Johns Hopkins University School of Medicine, suggests myocarditis caused by COVID-19 may be a relatively rare occurrence.

30 Oct 2020

Social threat can change a specific brain region

Our brains are wired to protect us from threats. For social animals like humans, threats often come from other members of our own species when there is conflict over food, mates, or territory.

30 Oct 2020

"Training" the immune system with β-glucan compound may improve immune recovery

Immunotherapies, such as checkpoint inhibitor drugs, have made worlds of difference for the treatment of cancer.Most clinicians and scientists understand these drugs to act on what's known as the adaptive immune system, the T cells and B cells that respond to specific threats to the body.

30 Oct 2020

Seroprevalence and immune response to SARS-CoV-2 in Paris

François Anna et al. published this study in a recent medRxiv* preprint paper, where they present the results of assessing the serological response in the selected population. They tested for specific IgG response against the SARS CoV-2 Nucleoprotein and Spike protein and performed a pseudo-neutralization assay in sera of urban dwellers in Paris.

30 Oct 2020

Research projects receive BTCA grants to develop novel drugs for various diseases

Five research projects with exceptional promise to deliver new life-changing and health-altering therapies have received the inaugural Blavatnik Therapeutics Challenge Awards (BTCA) at Harvard Medical School.

30 Oct 2020

Medical Research News

Decision conflict may lead to less favorable treatment outcomes in cancer patients

Study reveals molecular mechanism that increases the invasiveness of radioresistant cancer cells

Children with multiple islet autoantibodies are more likely to progress to type 1 diabetes

Study examines link between SARS-CoV-2 genomic load and COVID-19 patient outcomes

Addictive drug displays different acute pharmacology and synaptic plasticity

SARS-CoV-2 spike proteins can directly impact the blood-brain barrier

Novel approach can help measure antibodies against SARS-CoV-2

Research shows some COVID-19 patients experience long-lasting skin symptoms

Study shows statins can have adverse effects on certain organs

Researchers identify distinct link between autism and brain cell abnormalities

Scientists develop new model of coronavirus diffusion through a community

Study: ICE detention centers experienced repeated outbreaks of vaccine-preventable illnesses

Study: Toxins produced by tube-dwelling anemones have pharmacological potential

Penn State and Stanford University collaborate to develop two-hour sepsis test

RNI researchers to study the impact of excessive speeds on the human brain, body

COVID-19-related myocarditis may be a relatively rare occurrence, indicates study

Social threat can change a specific brain region

"Training" the immune system with β-glucan compound may improve immune recovery

Seroprevalence and immune response to SARS-CoV-2 in Paris

Research projects receive BTCA grants to develop novel drugs for various diseases

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

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