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$Low physical function and low muscle mass increase risk for bone loss after hip fracture$

Low physical function and low muscle mass increase risk for bone loss after hip fracture

Low physical function and low muscle mass after hip fracture increased the risk for accelerated bone deterioration in older hip fracture patients. Acknowledgement of the risk factors is important for bone health and overall recovery.

15 Jun 2020

New project could help healthcare providers plan for coronavirus consequences

Could COVID-19 harm patients after the infection has gone? Members of the EUROMENE COST Action are adapting their work on chronic fatigue syndrome to coronavirus patients.

15 Jun 2020

Vitamin K may offer protective health benefits as we age, study suggests

A new, multi-ethnic study found older adults with low vitamin K levels were more likely to die within 13 years compared to those whose vitamin K levels were adequate.

15 Jun 2020

Biomarkers needed to support the diagnosis of frontotemporal lobar degeneration

Biomarkers to support the diagnosis of frontotemporal lobar degeneration and to assess the severity and expected prognosis of the disease are needed.

15 Jun 2020

Tumor-resident T cell levels underlie improved survival in throat cancer patients

Research led by the Centenary Institute has discovered that immune cells accumulating within the tumor environment, called tumour-resident T cells, are a critical determinant in survival rates of patients suffering from throat cancer.

15 Jun 2020

New study investigates the impact of COVID-19 on sleep

An international group of researchers led by Professor Colin Espie from the Nuffield Department of Clinical Neurosciences at the University of Oxford is investigating the impact of the COVID-19 pandemic on sleep and daily rhythms in adults.

15 Jun 2020

Researchers are developing new diagnostic tool for rapid detection of coronavirus

Coronavirus diagnostics currently require centralized facilities and collection/distribution of swabs and results are 'next day'.

15 Jun 2020

New nonsurgical treatment reduces pain, improves function in patients with "frozen shoulder"

A new nonsurgical treatment decreases errant blood flow in the shoulder to quickly reduce pain and improve function in patients with adhesive capsulitis, also known as "frozen shoulder,"

15 Jun 2020

House-call model in rural Indiana helps reduce emergency department use, hospital readmissions

Interventional radiologists participating in a collaborative house call model in rural Indiana helped reduce emergency department use by 77 percent and hospital readmissions by 50 percent for nearly 1,000 elderly homebound patients with chronic illnesses, according to a research abstract presented during a virtual session of the Society of Interventional Radiology's 2020 Annual Scientific Meeting on June 13.

15 Jun 2020

New treatment may improve the quality of life for patients with mesothelioma

A novel treatment for advanced mesothelioma is safe and effective and may improve the quality of life for patients who have few treatment options, according to a research abstract presented during a virtual session of the Society of Interventional Radiology's 2020 Annual Scientific Meeting on June 14.

15 Jun 2020

Chimeric reference standards for validating controls in SARS-CoV-2 tests

A preliminary study by researchers from the Garvan Institute of Medical Research and the University of New South Wales and published on the preprint server bioRxiv in June 2020 reports the use of chimeric design to produced reference standards for diagnostic tests. This could allow a highly flexible approach to the development of different genetic features in the same test, even for organisms that are not directly related.

15 Jun 2020

New MRI techniques can improve outcomes in patients with Parkinson's disease

Recently developed MRI techniques used to more precisely target a small area in the brain linked to Parkinson's disease and essential tremor may lead to better outcomes without surgery and with less risk of negative effects, a new study led by UT Southwestern researchers suggests.

15 Jun 2020

Tuberculosis and polio vaccines may offer temporary protection against SARS-CoV-2

As the world grapples with the coronavirus disease (COVID-19) pandemic, scientists race to develop an effective vaccine to protect against the deadly SARS-CoV-2 virus. While potential vaccines are still being developed and tested, researchers propose that existing vaccines could give the immune system a temporary boost to ward off infection.

14 Jun 2020

Glycans "lock and load" the SARS-CoV-2 spike protein for infection

A new study by scientists from the University of California San Diego, USA and Maynooth University, Ireland and published on the preprint server bioRxiv* in June 2020 reports preliminary results showing that the spike protein of the SARS-CoV-2, as well as its glycan coat, has “hitherto unseen functional and structural” properties. These may be useful in designing novel therapeutics to target this molecule.

14 Jun 2020

Hydroxychloroquine ineffective in animal SARS-CoV-2 infection

A new study by scientists from the U.S and U.K. and published on the preprint server bioRxiv in June 2020 reports that there is no evidence of efficacy for the drug hydroxychloroquine (HCQ) against infection with SARS-CoV-2 in hamsters or macaque models. This finding does not support the current widespread prophylactic and therapeutic use of HCQ in COVID-19.

14 Jun 2020

Steroidal drugs subvert SARS-CoV-2 interaction with ACE2 receptors

A new study by Italian researchers and published online on the preprint server bioRxiv* in June 2020 reports the ability of several existing steroidal drugs to reduce the binding of the SARS-CoV-2 to the ACE2 receptor. This could help define newer strategies using viral entry blockers to reduce viral load.

14 Jun 2020

Remdesivir prevents replication of SARS-CoV-2 in human intestinal organoids

A new German study published on the preprint server bioRxiv* in June 2020 shows that the drug remdesivir can reduce the replication of SARS-CoV-2 in human intestinal organoids.

14 Jun 2020

Factors that determine COVID-19 mortality

A potentially important new study by MIT researchers and published on the preprint server medRxiv* in June 2020 shows that COVID-19 death rates in U.S. states correlate with several factors like commuting to work, temperatures, and geographical location, but not with ICU beds, obesity or poverty. This work, if validated, could help identify the actual contributing factors that shape mortality rates across the USA.

14 Jun 2020

Effect of human genes on severity and infectivity of SARS-CoV-2

Now, a new paper published on the preprint server medRxiv* reports the results of an analysis of the association between the genetic variants in the patients and the clinical progression of the disease. The study included 332 patients hospitalized with COVID-19 in a single-center, with widely varying laboratory and clinical features. There were 25, 12, and 17 patients with asymptomatic, mild, and critical disease.

14 Jun 2020

An entire trimeric S-protein of SARS-CoV-2 is necessary for protective immune response

Researchers from Seattle Children's Research Institute and the University of Washington described a high-throughput and rapid technique to quantify circulating levels of functional antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), suggesting that the entire viral spike protein should be used to characterize the immune response. Their paper is currently available on the medRxiv* preprint server.

14 Jun 2020

Medical Research News

Low physical function and low muscle mass increase risk for bone loss after hip fracture

New project could help healthcare providers plan for coronavirus consequences

Vitamin K may offer protective health benefits as we age, study suggests

Biomarkers needed to support the diagnosis of frontotemporal lobar degeneration

Tumor-resident T cell levels underlie improved survival in throat cancer patients

New study investigates the impact of COVID-19 on sleep

Researchers are developing new diagnostic tool for rapid detection of coronavirus

New nonsurgical treatment reduces pain, improves function in patients with "frozen shoulder"

House-call model in rural Indiana helps reduce emergency department use, hospital readmissions

New treatment may improve the quality of life for patients with mesothelioma

Chimeric reference standards for validating controls in SARS-CoV-2 tests

New MRI techniques can improve outcomes in patients with Parkinson's disease

Tuberculosis and polio vaccines may offer temporary protection against SARS-CoV-2

Glycans "lock and load" the SARS-CoV-2 spike protein for infection

Hydroxychloroquine ineffective in animal SARS-CoV-2 infection

Steroidal drugs subvert SARS-CoV-2 interaction with ACE2 receptors

Remdesivir prevents replication of SARS-CoV-2 in human intestinal organoids

Factors that determine COVID-19 mortality

Effect of human genes on severity and infectivity of SARS-CoV-2

An entire trimeric S-protein of SARS-CoV-2 is necessary for protective immune response

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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