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Scientists lay out a novel rationale for COVID-19 drug design

American and Polish scientists, reporting Oct. 16 in the journal Science Advances, laid out a novel rationale for COVID-19 drug design - blocking a molecular "scissor" that the virus uses for virus production and to disable human proteins crucial to the immune response.

19 Oct 2020

Dolutegravir is a first-line treatment for people newly diagnosed with HIV

A new study by UBC researchers is set to change international treatment recommendations for people who are newly diagnosed with HIV--an update that could affect nearly two million people per year worldwide.

19 Oct 2020

Engineers visualize how speaking spreads a virus

A team of researchers and engineers at Princeton University has provided a visualization of how speaking produces and expels saliva droplets into the air. The smallest droplets can be inhaled by people, which is the primary mode of transmission of infections such as COVID-19.

19 Oct 2020

Study of patterns of social contacts early on in COVID-19 pandemic

The coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has compelled people worldwide to quarantine. To mitigate the transmission of SARS-CoV-2, countries and workplaces have been under varying stages of lockdown since the detection of the infection in December 2019 in Wuhan, China.

19 Oct 2020

Concerti algorithm identifies intra-patient heteroplasmies in SARS-CoV-2 patients

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus that emerged in Wuhan, China, in late 2019 has caused the ongoing coronavirus disease 2019 (COVID-19) pandemic, which has affected more than 39.8 million lives globally and claimed over 1.11 million deaths to date.

18 Oct 2020

Sinopharm's candidate SARS-CoV-2 vaccine BBIBP-CorV shows promise in clinical trials

Researchers in China have conducted a phase 1/2 trial demonstrating the safety, tolerability, and immunogenicity of a candidate vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent responsible for the current coronavirus disease 2019 (COVID-19) pandemic.

18 Oct 2020

Future waves of COVID-19 will likely lead to further school closures

Researchers in the UK have warned that given how future waves of coronavirus disease 2019 (COVID-19) seem to be inevitable, it is likely that schools will be put under further pressure to close.

18 Oct 2020

Comparative analysis reveals common vulnerabilities across coronaviruses

Three lethal human respiratory syndromes associated with coronavirus (CoV) infections have emerged in the past two decades. They are severe acute respiratory syndrome (SARS) in 2002, Middle East respiratory syndrome (MERS) in 2012, and coronavirus disease 2019 (COVID-19) in 2019.

18 Oct 2020

WHO study finds Remdesivir and other repurposed drugs ineffective in COVID-19

A large-scale randomized trial has recently been conducted by the World Health Organization (WHO) to evaluate the efficacy of four repurposed antiviral medicines, including Remdesivir, Hydroxychloroquine, Lopinavir, and Interferon, currently used to treat hospitalized coronavirus disease 2019 (COVID-19) patients.

18 Oct 2020

Return to college classes tied to a 9 percent increase in COVID-19 cases, study finds

Since a vast majority of colleges and universities in the country are bringing students back for in-person instruction amid the COVID-19 pandemic, the researchers from the University of Georgia wanted to determine the effect of this return to campus on the viral case growth in countries with a significant college student population, compared to non-college countries.

18 Oct 2020

Obesity changes ACE2 and TMPRSS2 expression in mice: Implications for COVID-19

Researchers studying young obese mice found that expression of ACE2, a receptor in host cells that binds to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is higher in the lungs and trachea of obese mice. The finding could partly explain why obesity is a high-risk factor for COVID-19.

18 Oct 2020

Study provides possible explanation for progressive course of multiple sclerosis in mice

People with multiple sclerosis gradually develop increasing functional impairment. Researchers at Karolinska Institutet in Sweden have now found a possible explanation for the progressive course of the disease in mice and how it can be reversed.

16 Oct 2020

New tool can provide non-invasive decision support for NSCLC treatment

Personalized treatment options for patients with lung cancer have come a long way in the past two decades.

16 Oct 2020

Telemedicine use in the ER can yield positive results for patients and providers

Telemedicine has become more common given the current global pandemic. COVID-19 has limited doctor's office and hospital visits to ensure safety for everyone.

16 Oct 2020

Tracing lineage to demonstrate direct astrocyte-to-neuron conversion in mouse brain

Regeneration of functional new neurons to repair injured human brain is a long-term unsolved problem up till today.

16 Oct 2020

New study suggests some sedentariness isn’t all bad

It's generally accepted health advice that adults of all ages should sit less, move more, and engage in regular exercise to feel better and reduce the risk of chronic diseases.

16 Oct 2020

Study examines how international travel restrictions have affected COVID-19 mortality

Travel restrictions implemented early on in the pandemic have been crucial in slowing the spread of the coronavirus and keeping death rates low.

16 Oct 2020

Scientists receive £265,000 to investigate link between vascular dementia and heart disease

Scientists from the University of Sheffield and University of Manchester have been awarded £265,000 from the British Heart Foundation, to investigate the links between vascular dementia and heart disease, and test whether a drug currently used to treat arthritis could also be used as a treatment for vascular dementia.

16 Oct 2020

Key lessons from San Diego's Hepatitis A outbreak can be applied to COVID-19 pandemic

In an age when many people get their news from social media, ensuring health information is communicated accurately and understood clearly is critical, especially during infectious disease outbreaks.

16 Oct 2020

Alzheimer's disease: Impaired blood flow in the brain correlated with tau buildup

A new Alzheimer's study found that impaired blood flow in the brain is correlated with the buildup of tau tangles, a hallmark indicator of cognitive decline.

16 Oct 2020

Medical Research News

Scientists lay out a novel rationale for COVID-19 drug design

Dolutegravir is a first-line treatment for people newly diagnosed with HIV

Engineers visualize how speaking spreads a virus

Study of patterns of social contacts early on in COVID-19 pandemic

Concerti algorithm identifies intra-patient heteroplasmies in SARS-CoV-2 patients

Sinopharm's candidate SARS-CoV-2 vaccine BBIBP-CorV shows promise in clinical trials

Future waves of COVID-19 will likely lead to further school closures

Comparative analysis reveals common vulnerabilities across coronaviruses

WHO study finds Remdesivir and other repurposed drugs ineffective in COVID-19

Return to college classes tied to a 9 percent increase in COVID-19 cases, study finds

Obesity changes ACE2 and TMPRSS2 expression in mice: Implications for COVID-19

Study provides possible explanation for progressive course of multiple sclerosis in mice

New tool can provide non-invasive decision support for NSCLC treatment

Telemedicine use in the ER can yield positive results for patients and providers

Tracing lineage to demonstrate direct astrocyte-to-neuron conversion in mouse brain

New study suggests some sedentariness isn’t all bad

Study examines how international travel restrictions have affected COVID-19 mortality

Scientists receive £265,000 to investigate link between vascular dementia and heart disease

Key lessons from San Diego's Hepatitis A outbreak can be applied to COVID-19 pandemic

Alzheimer's disease: Impaired blood flow in the brain correlated with tau buildup

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

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