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Hyperprogression to immune blockade followed by a response with cabozantinib in metastatic RCC

Volume 11, Issue 22 of @Oncotarget reported that more and more patients receive first-line treatment with immunotherapy combinations and not all patients respond in metastatic renal cell carcinoma.

10 Jun 2020

Anticardiolipin antibodies and COVID-19

A new study has shown that anticardiolipin antibodies are associated with the novel coronavirus infection or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes COVID-19.

10 Jun 2020

Researchers evaluate survivin expression in neuroendocrine tumors

Volume 11, Issue 23 of @Oncotarget reported that tissue microarrays of 132 patients were stained for survivin using immunohistochemistry and correlated with outcomes.

10 Jun 2020

Mozart listening associated with reduced seizure frequency in patients with epilepsy

A new clinical research study by Dr. Marjan Rafiee and Dr. Taufik Valiante of the Krembil Brain Institute at Toronto Western Hospital, part of University Health Network, has found that a Mozart composition may reduce seizure frequency in patients with epilepsy.

10 Jun 2020

Unique antiviral action of cholesterol 25-hydroxylase against SARS-CoV-2

A new study by U.S. and Chinese researchers, currently available on the bioRxiv* preprint server, demonstrates how cholesterol 25-hydroxylase and its enzymatic product 25-hydroxycholesterol can inhibit membrane fus

10 Jun 2020

Study assesses the acute impact of cannabis among real-world users

Smoking high-potency marijuana concentrates boosts blood levels of THC more than twice as much as smoking conventional weed, but it doesn't necessarily get you higher, according to a new study of regular users published today by University of Colorado Boulder researchers.

10 Jun 2020

COVID-19 mouse model could accelerate the search for treatments, vaccines

The global effort to quickly develop drugs and vaccines for COVID-19 has been hampered by limited numbers of laboratory mice that are susceptible to infection with SARS-CoV-2, the virus that causes COVID-19.

10 Jun 2020

Texas A&M scientists develop 2D nanosheets to advance cancer treatment

Scientists in the Department of Biomedical Engineering at Texas A&M University are developing new ways to advance the field of regenerative medicine and cancer treatment. They are developing a 2D nanosheet that is 1,000 times smaller than a strand of hair.

10 Jun 2020

COVID-19 pandemic impacts mental, physical health of people with obesity

The COVID-19 pandemic is having a significant impact on people with obesity as they struggle to manage their weight and mental health during shelter-in-place orders, according to research led by The University of Texas Health Science Center at Houston and UT Southwestern.

10 Jun 2020

Blood type plays role in SARS-CoV-2 infection

A new meta-analysis from Iran, available on the medRxiv preprint server, showed that the blood group A could be considered a partial risk factor for infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), whereas the blood group O may act as a protective factor; conversely, no significant associations were observed between specific blood groups and coronavirus disease (COVID-19) mortality.

10 Jun 2020

Key enzyme that contributes to eczema identified

Researchers at the University of British Columbia (UBC) and Vancouver Coastal Health Research Institute have identified a key enzyme that contributes to eczema, which may lead to better treatment to prevent the skin disorder's debilitating effects.

10 Jun 2020

UMSOM researchers identify how certain gene mutations cause ALS

Researchers at the University of Maryland School of Medicine have identified how certain gene mutations cause amyotrophic lateral sclerosis, also known as Lou Gehrig's disease.

10 Jun 2020

Cleveland Clinic receives $7.2 million to improve accuracy of MS diagnoses

The National Institutes of Health has awarded $7.2 million to a Cleveland Clinic-led research team to improve accuracy of multiple sclerosis (MS) diagnoses.

10 Jun 2020

Seroprevalence of IgM and IgG against SARS-CoV-2 in China

A new study published in the journal Nature Medicine in June 2020 reports the seroprevalence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) across China. This may help to understand the actual prevalence of the virus in the current pandemic.

10 Jun 2020

Depression among 70-year-olds may be associated with gender expression

Over time, depression has decreased among older women. But it is still nearly twice as frequent as among older men.

10 Jun 2020

Study shows safety of new cell therapy approaches for kidney transplant recipients

A large international study coordinated by University Hospital Regensburg and Charité - Universitätsmedizin Berlin has demonstrated the safety of new cell therapy approaches for use in kidney transplant recipients.

10 Jun 2020

Specific immune signature identified in COVID-19 patients

Researchers at King’s College London and collaborators have identified an “immune signature” that could help researchers better understand coronavirus disease 2019 (COVID-19) and serve as a valuable resource for predicting patient prognosis and informing clinical risk-based stratification.

10 Jun 2020

Expanding flu vaccine coverage could reduce inappropriate antibiotic prescribing

Up to 76 percent of all outpatient antibiotic prescriptions in the United States may be inappropriate, with peak prescribing associated with the flu season.

10 Jun 2020

New insights into causes for age-related orientation problems

Our sense of direction tends to decline with age. In the scientific journal "Nature Communications", researchers from the German Center for Neurodegenerative Diseases and experts from the USA report on new insights into the causes of this phenomenon.

10 Jun 2020

Mitigating "second wave" COVID-19 risk to health frontliners and patients

Researchers at University College London have made important discoveries about the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among frontline healthcare workers that could help to inform new policies for protecting staff and patients in the future.

10 Jun 2020