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SARS-CoV-2 genome variants in India

A new study published online on the preprint server bioRxiv in June 2020 surveys the genetic diversity of SARS-CoV-2 strains in India.

7 Jun 2020

SARS-CoV-2 invasion of central nervous system through olfactory tract

As the COVID-19 pandemic continues to claim lives throughout the world, the evidence is mounting that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects the respiratory tract as well as the central nervous system. Now, a new study by German researchers published on the preprint server bioRxiv in June 2020 describes various neurological manifestations of COVID-19, as well as the underlying pathophysiology.

7 Jun 2020

Tocilizumab in COVID-19 patients on mechanical ventilation

Now, a new study by researchers from the University of Michigan and published on the online preprint server medRxiv* in June 2020 shows that the cytokine inhibitor tocilizumab could have a favorable effect on survival in the most severely infected patients who require mechanical ventilation. This needs to be confirmed by clinical trials.

7 Jun 2020

New strategy may facilitate development of multi-epitope peptide vaccine against SARS-CoV-2

By combining T and B lymphocyte analysis with manufacturability heuristic, researchers from the US and Germany proposed a set of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine peptides to use in subsequent animal studies and clinical trials. Their paper is currently available on the bioRxiv preprint server.

7 Jun 2020

Kidney enzyme renalase a potential therapy for severe COVID-19

Researchers from Yale School of Medicine have discovered that a low blood level of an enzyme called renalase is associated with severe coronavirus disease 2019 (COVID-19).

7 Jun 2020

Zinc-finger antiviral protein makes SARS-CoV-2 highly susceptible to interferons

By looking into zinc-finger antiviral proteins (ZAP), a new study from Germany and the United Kingdom (UK) and available on the preprint server bioRxiv suggests that zoonotic transmission of a coronavirus with a specific genetic make-up facilitated the pandemic spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but also its sensitivity to interferons.

7 Jun 2020

Lockdown adversities could affect sleep and mental health

Researchers at University College London warn that the adversities people are facing in the UK as a result of lockdown during the coronavirus disease 2019 (COVID-19) pandemic may be causing sleep problems that could affect mental health.

7 Jun 2020

People suffering from rheumatoid arthritis with increased disease activity have high thrombosis risk

People suffering from rheumatoid arthritis with increased disease activity are more often affected by thrombosis.

5 Jun 2020

Study investigates combined effects of cancer therapy and inherited genetics

Scientists at St. Jude Children's Research Hospital are studying the combined effect of cancer treatments and inherited mutations in DNA-repair genes.

5 Jun 2020

Approved drug could help dampen massive immune response associated with severe COVID-19

The drug acalabrutinib, FDA-approved for the treatment of several types of B cell cancers, improved the oxygenation levels and decreased molecular markers of inflammation in a majority of 19 patients hospitalized for the treatment of severe COVID-19, according to a new study by Mark Roschewski and colleagues.

5 Jun 2020

Researchers receive $1.5 million grant to study impact of cannabis use on Indigenous oral health

A multidisciplinary team from the University of Toronto, with experts from the Faculty of Dentistry and the Waakebiness-Bryce Institute for Indigenous Health at the Dalla Lana School of Public Health have been awarded a five year, $1.5 million grant from the Canadian Institutes of Health Research to study the impact of cannabis use on the oral health of Indigenous populations.

5 Jun 2020

Discovery of new killing mechanism could help design improved teixobactin-based drugs

Scientists at the University of Liverpool and University of Utrecht have taken another step forward on their quest to develop a viable drug based on teixobactin - a new class of potent natural antibiotic capable of killing superbugs.

5 Jun 2020

George Mason researcher examining the use of Brilacidin for treatment of coronavirus infections

Aarthi Narayanan, Assistant Professor, National Center for Biodefense and Infectious Diseases, received $35,000 from Innovation Pharmaceuticals, Inc., for a project in which she is examining the use of Brilacidin for the treatment of coronavirus infections.

5 Jun 2020

Creating hair-bearing human skin becomes a reality

For more than 40 years, scientists and commercial companies have been recreating human skin in laboratories around the world. Yet all of these products lack important aspects of normal skin--hair, nerves, and fat.

5 Jun 2020

Bystander CPR benefits outweigh the risks of COVID-19 infection

Analysis of Seattle emergency medical services and hospital data from January 1 to April 15, 2020, indicates bystander CPR is a lifesaving endeavor whose benefits outweigh the risks of COVID-19 infection, according to a new article published yesterday in the American Heart Association's flagship journal Circulation.

5 Jun 2020

UTHSC researchers receive NIH award for opioid addiction studies

A team of University of Tennessee Health Science Center researchers in the College of Medicine recently received a National Institutes of Health award to study how genetic differences may explain why some people are more susceptible to opioid addiction than others.

5 Jun 2020

Novel disease may lead to a better understanding of cystic fibrosis

Cystic fibrosis is the most frequent severe inherited disorder worldwide. Every year, hundreds of families are confronted with this diagnosis - and to date, there is no cure for this disease that mainly affects the respiratory system.

5 Jun 2020

New educational program improves bike helmet use by urban children

To reduce the number of traumatic brain injuries in children, a team of health care professionals at the Johns Hopkins University School of Medicine and the Johns Hopkins Bloomberg School of Public Health is urging emergency room physicians to help ensure that youngsters are thoroughly educated on the proper use of bike helmets, especially in urban environments where most severe head injuries occur.

5 Jun 2020

NMDA receptors play key role in sleep deficits that accompany psychiatric disorders

Sofya Kulikova, a researcher at HSE University in Perm, is part of an international research team that has discovered potential mechanisms that explain the sleep spindle deficit in electroencephalograms (EEG) of people with schizophrenia. The article was published in the Schizophrenia Research on June 5.

5 Jun 2020

GMU researchers studying effect of cannabidiol on exosome release

Fatah Kashanchi, Professor, Laboratory of Molecular Virology, School of Systems Biology, and Lance Liotta, Co-Director, Applied Proteomics and Molecular Medicine, are working to mitigate virally driven HIV pathenogenesis in the central nervous system.

5 Jun 2020

Medical Research News

SARS-CoV-2 genome variants in India

SARS-CoV-2 invasion of central nervous system through olfactory tract

Tocilizumab in COVID-19 patients on mechanical ventilation

New strategy may facilitate development of multi-epitope peptide vaccine against SARS-CoV-2

Kidney enzyme renalase a potential therapy for severe COVID-19

Zinc-finger antiviral protein makes SARS-CoV-2 highly susceptible to interferons

Lockdown adversities could affect sleep and mental health

People suffering from rheumatoid arthritis with increased disease activity have high thrombosis risk

Study investigates combined effects of cancer therapy and inherited genetics

Approved drug could help dampen massive immune response associated with severe COVID-19

Researchers receive $1.5 million grant to study impact of cannabis use on Indigenous oral health

Discovery of new killing mechanism could help design improved teixobactin-based drugs

George Mason researcher examining the use of Brilacidin for treatment of coronavirus infections

Creating hair-bearing human skin becomes a reality

Bystander CPR benefits outweigh the risks of COVID-19 infection

UTHSC researchers receive NIH award for opioid addiction studies

Novel disease may lead to a better understanding of cystic fibrosis

New educational program improves bike helmet use by urban children

NMDA receptors play key role in sleep deficits that accompany psychiatric disorders

GMU researchers studying effect of cannabidiol on exosome release

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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