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New polymeric heart valve could be a life-saver

Millions of persons around the world suffer from diseased and damaged heart valves. These patients require valve repair surgeries, and often when that is not possible, they need to take blood-thinners for life to prevent complications.

30 Jun 2020

Oral hygiene and severity of COVID-19 – the connection

Their study titled, “Could there be a link between oral hygiene and the severity of SARS-CoV-2 infections?” was published in the latest issue of the journal British Dental Journal.

30 Jun 2020

Herd immunity in the U.S. unlikely

The race to develop an effective vaccine against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is on, with many vaccine candidates entering the human trial phase. When a vaccine is developed and introduced into the population at scale, it triggers herd immunity, with many people immune to the infectious disease.

30 Jun 2020

New swine flu strain with pandemic potential found in China

As the world grapples with a novel coronavirus pandemic, a new strain of swine flu that can trigger a pandemic has been reported.

30 Jun 2020

Striking CryoEM image of SARS-CoV-2

A new study by researchers from the UK and Germany and published on the preprint server bioRxiv in June 2020 reports the results of a detailed study of the S protein on the intact virus, using cryoelectron microscopy (cryoEM) and tomography. This could help understand the conformation of the S protein on the virion and how it interacts with neutralizing antibodies.

30 Jun 2020

Study provides first estimates of healthy working life expectancy for adults aged 50

A new study has estimated that on average people in England from age 50 can expect to be healthy and in work for nine more years.

30 Jun 2020

Large-scale analysis of COVID-19 risk among different groups of UK hospital staff

Staff who shared a household with an infected person were at the greatest risk of infection, and those working in COVID-19-facing areas were also at an increased risk. Other groups that were identified as a high risk included Black and Asian individuals, porters, and cleaners.

30 Jun 2020

Study links unexpected hospital stays to negative outcomes in head and neck cancer patients

Patients who were unexpectedly hospitalized for dehydration, fever or other ailments while undergoing radiation treatment for head and neck cancers were at a higher risk for less favorable outcomes, a new study from Roswell Park Comprehensive Cancer Center reports.

30 Jun 2020

Researchers develop technique for personalizing stomach cancer therapy

Researchers from the Moscow Institute of Physics and Technology and their colleagues have developed the first technique for personalizing stomach cancer therapy based on RNA sequencing of tumor cells. The study, supported by the Russian Science Foundation, was published in Cold Spring Harbor Molecular Case Studies.

30 Jun 2020

Study explores time trends in pregnancy-related outcomes among women with type 1 diabetes

Researchers from the Joslin Diabetes Center investigated time trends in pregnancy-related outcomes among women with type 1 diabetes between 2004 and 2017, and found that the percentage of mothers with excess weight gain during pregnancy as well as the use of insulin pumps and CGMs increased significantly, while the prevalence of nephropathy fell dramatically to zero.

30 Jun 2020

Specific SARS-CoV-2 genetic elements found in different insect species

In a recent bioRxiv paper, researchers from Norway and the US demonstrate the presence of a highly conserved, mobile genetic element (thus far with unknown function) in genomes of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and a large number of insects – opening the door for hitherto unexplored treatment opportunities.

30 Jun 2020

New study aims to identify how to better protect disabled children

How effective are we at safeguarding disabled children? An important new study which seeks to understand how to can better protect disabled children and young people from abuse starts this week.

30 Jun 2020

'Mini-brains' can be infected by SARS-CoV-2 virus

A multidisciplinary team from two Johns Hopkins University institutions, including neurotoxicologists and virologists from the Bloomberg School of Public Health and infectious disease specialists from the school of medicine, has found that organoids (tiny tissue cultures made from human cells that simulate whole organs) known as "mini-brains" can be infected by the SARS-CoV-2 virus that causes COVID-19.

30 Jun 2020

Research shows IQGAP1 as a common target in variants of triple negative breast cancer

The cover for issue 26 of Oncotarget features Figure 6, "Mislocalization of IQGAP1-BRCA1 in human TNBC tumors phenocopies the dominant mutants and the TNBC cells," by Osman, et al. and reported that IQGAP1 is a signaling scaffold implicated in TNBC, but its mechanism is unknown.

30 Jun 2020

Potential new biomarker could improve COVID-19 diagnosis

Researchers at Montpellier University Hospital have discovered that an interferon-inducible receptor expressed on monocytes could be a useful biomarker for the rapid triaging of patients suspected to have severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

30 Jun 2020

In-home portable air cleaners reduce particulate exposure for cardiac patients

Using an in-home portable air cleaner (PAC) can significantly reduce exposure to fine-particle air pollutants - a major risk factor for cardiovascular events in people with pre-existing heart disease, reports a pilot study in the July issue of Journal of Cardiopulmonary Rehabilitation and Prevention.

30 Jun 2020

New study will help primary care nurses better care for dementia patients

McLean Hospital's Brent P. Forester, MD, MSc, is heading a new study of a training model to help primary care nurses better care for patients with dementia.

30 Jun 2020

Alternative antibiotics for unverified penicillin allergies likely unnecessary

Hospitalized patients who report an allergy to penicillin are often prescribed alternative antibiotics for infection that can be harmful, even though diagnostic testing or evaluations would show that the vast majority of these reported allergies could be disproven, according to researchers from Massachusetts General Hospital.

30 Jun 2020

Novel brain pathology could improve diagnosis, treatment of neurodegenerative diseases

Bristol scientists have discovered a novel pathology that occurs in several human neurodegenerative diseases, including Huntington's disease.

30 Jun 2020

A semi-empirical model to reproduce the brain states from wakefulness to deep sleep

The human brain is a complex system comprising 1010 non-linear units (neurons) that interact in 1015 sites (synapses).

30 Jun 2020

Medical Research News

New polymeric heart valve could be a life-saver

Oral hygiene and severity of COVID-19 – the connection

Herd immunity in the U.S. unlikely

New swine flu strain with pandemic potential found in China

Striking CryoEM image of SARS-CoV-2

Study provides first estimates of healthy working life expectancy for adults aged 50

Large-scale analysis of COVID-19 risk among different groups of UK hospital staff

Study links unexpected hospital stays to negative outcomes in head and neck cancer patients

Researchers develop technique for personalizing stomach cancer therapy

Study explores time trends in pregnancy-related outcomes among women with type 1 diabetes

Specific SARS-CoV-2 genetic elements found in different insect species

New study aims to identify how to better protect disabled children

'Mini-brains' can be infected by SARS-CoV-2 virus

Research shows IQGAP1 as a common target in variants of triple negative breast cancer

Potential new biomarker could improve COVID-19 diagnosis

In-home portable air cleaners reduce particulate exposure for cardiac patients

New study will help primary care nurses better care for dementia patients

Alternative antibiotics for unverified penicillin allergies likely unnecessary

Novel brain pathology could improve diagnosis, treatment of neurodegenerative diseases

A semi-empirical model to reproduce the brain states from wakefulness to deep sleep

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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