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Researchers discover cause for the lack of immune defense against tumors

One of the reasons why cancer develops is because regulatory cells inhibit the body's immune defense. Researchers under the helm of the Technical University of Munich have discovered a mechanism for identifying regulatory cells in tumor tissue that suppress an immune response.

29 Apr 2020

Kurome secures license to develop novel therapies for chemo-resistant cancer

Seed investor CincyTech announced the formation of Kurome Therapeutics ("Kurome"), a preclinical stage company developing novel therapies targeting cancer cells' adaptive resistance mechanisms beginning with hematopoietic, or blood cell, cancers.

29 Apr 2020

Study: Protein known to expand blood vessels works differently in males and females

A protein known to expand blood vessels -- key to controlling conditions like high blood pressure -- actually has different functions in males and females, new UC Davis Health research shows.

29 Apr 2020

Breakthrough study shows liquid biopsy test can safely detect 26 undiagnosed cancers

Results from a first-of-its-kind study of a multicancer blood test in more than 9,900 women with no evidence or history of cancer showed the liquid biopsy test safely detected 26 undiagnosed cancers, enabling potentially curative treatment.

29 Apr 2020

Researchers test existing anti-inflammatory drug in COVID-19 patients

An anti-inflammatory drug developed at Scripps Research 25 years ago is now being tested as a way to prevent acute respiratory distress in patients with COVID-19, the pandemic disease caused by the novel coronavirus.

29 Apr 2020

Study: E-cigarettes damage vascular function much like traditional cigarettes

Using e-cigarettes damages the arteries and blood vessel function much like smoking traditional cigarettes, according to new research published today in the Journal of the American Heart Association, an open access journal of the American Heart Association, and funded through the Tobacco Center of Regulatory Science of the American Heart Association, the leading voluntary health organization devoted to a world of longer, healthier lives.

29 Apr 2020

Researchers identify link between COVID-19 cure rate and regional selenium status

An international team of researchers, led by Professor Margaret Rayman at the University of Surrey, has identified a link between the Covid-19 cure rate and regional selenium status in China.

29 Apr 2020

A new platform to create drugs for people with hard-to-treat cancers

A new round of support will help a Purdue University-affiliated startup further develop a platform designed to create drugs for people with hard-to-treat cancers.

29 Apr 2020

Adolescent obesity carries higher thrombus risk later in life

Men with a history of obesity in their late teens are, in adult life, more at risk of a blood clot (thrombus) in a leg or lung, according to a study from the University of Gothenburg study shows.

29 Apr 2020

International study to evaluate the effects of COVID-19 in pregnancy launched

Researchers at the University of Oxford are today starting a large, international study to evaluate the effects of COVID-19 in pregnancy.

29 Apr 2020

Study with twins shows COVID-19 symptoms have genetic contribution

A new study published on the preprint server medRxiv from King's College, London, suggests that an individual's genetic makeup may contribute to how much a person is likely to be affected by COVID-19, or whether they are likely to be infected at all.

29 Apr 2020

Study reveals SARS-CoV-2 RNA cap structure

A new study published on the preprint server bioRxiv in April 2020 reports the discovery of the structure of the cap created by the novel coronavirus on virally encoded mRNAs. The finding could help create new antiviral strategies.

29 Apr 2020

'Smart sample pooling' for COVID-19 could solve test kit shortage problem

A new study from Pakistan suggests 'smart sample pooling' using population grouping with algorithms as a solution to the unavailability of test kits for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 is a virus that causes COVID-19 disease. The paper is published on the preprint server medRxiv on April 28, 2020.

29 Apr 2020

C-Path receives EMA’s letter of support to facilitate the diagnoses of type 1 diabetes

The Critical Path Institute (C-Path) today announced that its Type 1 Diabetes (T1D) Consortium has received a letter of support from the European Medicines Agency (EMA) to facilitate the development and validation of the proposed regulatory qualification of pancreatic islet autoantibodies commonly used in clinical practice to diagnose T1D: insulin autoantibodies, glutamic acid decarboxylase 65, and insulinoma antigen-2 autoantibodies as enrichment biomarkers for T1D clinical trials.

29 Apr 2020

How weather and demographics influence the COVID-19 spread

What can stop the spread of the novel coronavirus? A new study published in the preprint journal medRxiv in April 2020 debunks the idea that warmer and more humid conditions can hinder the pandemic from spreading with ease.

29 Apr 2020

Differences in reporting methods can over- or under-estimate the safety of drugs

An important goal of early-phase clinical trials is to discover a drug's possible side effects. But despite FDA guidelines seeking to standardize this reporting, a University of Colorado Cancer Center study finds significant variation in how drug side effects are reported, potentially making some drugs seem safer or less safe than they really are.

29 Apr 2020

How toxic are chloroquine and hydroxychloroquine to cells?

The spread of the pandemic disease COVID-19 caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has now reached almost every country of the world, with over 3.11 million cases and over 217,000 deaths as of April 29, 2020.

29 Apr 2020

Men are twice more likely to die of COVID-19 than women

There have been studies that have revealed that men are more likely to get more severe symptoms from COVID-19 disease and also more likely to die from complications of the disease. A new study corroborates these findings. The study titled, “Gender differences in patients with COVID-19: Focus on severity and mortality,” is published in the latest issue of the journal Frontiers in Public Health.

29 Apr 2020

Researchers receive ERC grant to speed up the diagnosis of autoimmune encephalitis

Autoimmune encephalitis (AE) is a disease that affects 2-3 people out of 100,000, in which our immune system attacks our own brain causing neurological and psychiatric symptoms.

28 Apr 2020

French scientists suggest nicotinic agonists could treat COVID-19

Contrary to the warnings issued by health agencies worldwide against cigarette smoking amid the coronavirus disease (COVID-19), a new paper suggests the possibility that nicotine, a component of tobacco, could prevent coronavirus infection.

28 Apr 2020