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Alzheimer's patients may need modified dosing regimens for selected drugs

Patients with Alzheimer's disease are often prescribed drugs for other conditions -- including diabetes or high blood pressure -- at the same doses as those without dementia.

15 Apr 2020

Aspirin associated with reduction in risk of several digestive tract cancers

Aspirin is associated with a reduction in the risk of developing several cancers of the digestive tract, including some that are almost invariably fatal, such as pancreatic and liver cancers.

15 Apr 2020

Bacterial metabolism of bile acids boosts generation of immune cells, study shows

A Ludwig Cancer Research study has discovered a novel means by which bacterial colonies in the small intestine support the generation of regulatory T cells--immune cells that suppress autoimmune reactions and inflammation.

15 Apr 2020

Review: The effect of probiotics in ameliorating altered CNS functions in neurological disorders

As per the WHO report, one in every four people are affected by a mental or neurological disorder at some point in their lives making mental disorders among the leading cause of ill-health and disability worldwide.

15 Apr 2020

Coronavirus able to survive near boiling point of water, study shows

A startling paper by a team of French scientists published in the preprint journal bioRxiv in April 2020 suggests that the novel coronavirus is capable of surviving at high temperatures. This could mean that laboratory technicians handling the virus are at danger of infection.

15 Apr 2020

Young people cite barriers to seeking help for eating disorders

A new study has found young people are leaving it 'too late' to seek help for eating disorders, citing fear of losing control over their eating or weight, denial, and failure to perceive the severity of the illness as reasons not to get professional advice.

15 Apr 2020

Unexpected benefit of COVID-19 lockdowns on the environment and health

The pandemic spreading over the world has affected over 185 countries and territories so far, with over 2 million cases and 134,354 deaths. In response, many countries and regions have enforced lockdowns, in addition to the almost universal recommendations for social distancing. One of the most significant impacts has been the effect on economic activity the world over.

15 Apr 2020

Vegetable intake before pregnancy reduces risk of preterm birth

A new study shows that women who eat vegetables regularly before becoming pregnant have a significantly lower risk of premature birth. The new study from the University of Queensland titled, "Prepregnancy dietary patterns and risk of preterm birth and low birth weight: findings from the Australian Longitudinal Study on Women's Health," was published in the latest issue of the journal The American Journal of Clinical Nutrition.

15 Apr 2020

COVID-19 modeling shows that social distancing is a must, must, must

A new study shows that using mathematical modeling and accounting for several factors such as age distribution and density of the population, a clearer picture of COVID-19 infection in a population could be gained. The study titled, "Level of under-reporting including under-diagnosis before the first peak of COVID-19 in various countries: Preliminary Retrospective Results Based on Wavelets and Deterministic Modeling," is published as an accepted manuscript in the journal Infection Control & Hospital Epidemiology.

15 Apr 2020

New coronavirus possibly circulated within humans before COVID-19 pandemic

Genetic variation analysis and the evidence of recombination events point towards the conclusion that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) might have circulated cryptically among humans for years, as reported by a recent paper on a preprint server bioRxiv.

15 Apr 2020

ACE2 genetic variants may influence coronavirus disease progression

Researchers in British Columbia have identified a set of gene variants that are likely to influence disease progression from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection to COVID-19 disease.

15 Apr 2020

Reprogramming skin cells into photoreceptors to restore vision in mice

Researchers have discovered a technique for directly reprogramming skin cells into light-sensing rod photoreceptors used for vision.

15 Apr 2020

Breastmilk influences accumulation of viruses in the infant gut

Even small amounts of breastmilk strongly influences the accumulation of viral populations in the infant gut and provides a protective effect against potentially pathogenic viruses, according to researchers who examined hundreds of babies in a study from the Perelman School of Medicine at the University of Pennsylvania.

15 Apr 2020

COVID-19 and type 2 diabetes have shared disease pathways, study finds

Individuals with diabetes are at increased risk for bacterial, parasitic and viral infections. New research published in Endocrine Reviews, a journal of the Endocrine Society, illuminates how intersections of the coronavirus infection (COVID-19) and type 2 diabetes may require new approaches in treatment for hospitalized patients.

15 Apr 2020

A gut-to-brain circuit drives sugar preference and may explain sugar cravings

By visualizing brain activity when the rodents consumed sugar versus artificial sweetener or water, researchers have identified a brain region that responds solely to sugar: the caudal nucleus of the solitary tract (cNST).

15 Apr 2020

New clinical trial seeks to find alternative ventilator solutions for COVID-19 patients

A new clinical trial led by the University of Warwick and Queen's University Belfast seeks to find alternatives to ventilators to treat patients who are critically ill with COVID-19.

15 Apr 2020

Childhood secondhand smoking exposure associated with poorer midlife cognitive function

A Finnish study coordinated by the Research Centre of Applied and Preventive Cardiovascular Medicine at the University of Turku, Finland, shows that exposure to parental smoking in childhood and adolescence is associated with poorer learning ability and memory in midlife.

15 Apr 2020

Exposure to heavy wildfire smoke may raise risk of out-of-hospital cardiac arrest

Exposure to heavy smoke during recent California wildfires raised the risk of out-of-hospital cardiac arrests up to 70%, according to new research published today in the Journal of the American Heart Association, the open access journal of the American Heart Association.

15 Apr 2020

Study shows possible way to effectively deliver RNA drugs to tumors

In recent years, RNA molecules, with the ability to affect or turn off pathogenic genes, have become promising drug candidates in several areas.

15 Apr 2020

Autism in males may result from problems in brain-based immune cells

Many cases of autism spectrum disorders may result from problems in immune cells that normally work to trim back unneeded brain connections in early life, suggests a new study led by scientists at Scripps Research.

15 Apr 2020