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DNA nanoswitches may provide an inexpensive platform to rapidly detect emerging viruses

Programmable DNA nanoswitches that bind to viral RNA in human body fluids may provide an inexpensive platform to rapidly detect a wide variety of emerging viruses, including SARS-CoV-2, according to a new study.

21 Aug 2020

New injectable drug could offer long-lasting protection from HIV with fewer side effects

Scientists have developed an injectable drug that blocks HIV from entering cells. They say the new drug potentially offers long-lasting protection from the infection with fewer side effects.

21 Aug 2020

Researchers discover new mechanism for anticancer drug resistance in gastric cancer

A joint project led by Kumamoto University (Japan) has discovered a new mechanism for anticancer drug resistance in gastric cancer.

21 Aug 2020

COVID-19 patients most likely readmitted to hospital for respiratory distress, study finds

This study describes characteristics of patients with COVID-19 who returned to the ER or required readmission to the hospital within 14 days of being discharged. Understanding what conditions impact these patient outcomes can help improve care during the hospital stay and after discharge.

21 Aug 2020

VUMC receives $34 million grant for nationwide convalescent plasma study

Vanderbilt University Medical Center has been awarded a one-year, $34-million grant by the National Center for Advancing Translational Sciences, part of the National Institutes of Health, to conduct a nationwide study of "convalescent plasma" as a treatment for COVID-19.

21 Aug 2020

CT scans used at a higher rate in children with cognitive impairment to diagnose appendicitis

Computed tomography (CT) is used at a higher rate than ultrasound in children with developmental and cognitive impairments to diagnose appendicitis, even though CT scans increase radiation risk in smaller bodies.

21 Aug 2020

New test can simplify the measurement of attitudes towards autistic people

Using a simple 'thermometer scale survey' to measure public attitudes towards people with autism could help improve public understanding and acceptance, say researchers.

21 Aug 2020

Study identifies several new microbes that cause dental caries

The human body is home to trillions of microbes. Through its natural functioning, much of the time, this ecosystem regulates our health.

21 Aug 2020

Researchers reproduce the pathogenesis of hereditary kidney disease from human iPS cells

Joint research, led by Kumamoto University in Japan, has successfully reproduced the pathogenesis of autosomal dominant polycystic kidney disease (ADPKD) from human iPS cells in vitro.

21 Aug 2020

Strong feelings of germ aversion and pathogen disgust associated with preventative behavior

Creeped out by cooties? Grossed out by germs? Squeamish about sickness? If so, then you might also find yourself engaging in more preventative health behaviors, like frequent handwashing and disinfecting your living environment, during the ongoing coronavirus pandemic.

21 Aug 2020

Artificial intelligence can help detect heart disease based on facial photos

Sending a "selfie" to the doctor could be a cheap and simple way of detecting heart disease, according to the authors of a new study published today (Friday) in the European Heart Journal .

21 Aug 2020

Women surgeons earn a disproportionate share of NIH research grants

Women are underrepresented in the field of academic surgery, but women surgeons are earning a disproportionate share of research grants from the National Institutes of Health, a new study has found.

21 Aug 2020

A new mechanism by which microtubule networks instruct neuronal polarity revealed

Prof. MENG Wenxiang's group from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences recently reported a new mechanism by which microtubule networks instruct neuronal polarity.

21 Aug 2020

Adolescents with “elevated" hunger hormone are more likely to develop post-traumatic stress disorder

Chronic stress increases a blood-based hormone called acyl-ghrelin for years after the initial traumatic stressor exposure in some adolescents, and those with elevated levels of the hormone are more likely to develop post-traumatic stress disorder (PTSD) and to experience more severe cases of the condition, according to a study conducted by researchers at the Icahn School of Medicine at Mount Sinai and published August 20 in JAMA Network Open.

21 Aug 2020

Dusp8 protein has regulatory effects on hypothalamic insulin sensitivity

The brain plays a major role in controlling our blood glucose levels. In type 2 diabetics this glucose metabolism brain control is often dysfunctional. Genetic components for this phenomenon have so far remained elusive.

21 Aug 2020

Key molecule can be used to assess prognosis of triple negative breast cancer

Hokkaido University scientists have shown that Interleukin-34 is a prognostic marker and drug target for Triple Negative Breast Cancer.

21 Aug 2020

Concussion can lead to long-term sleep problems, affect quality of life

Every year, thousands of people end up in the emergency room or hospital with minor head injuries, often diagnosed as concussions. Concussions usually result from falls, violence, bicycle accidents or sports injuries.

21 Aug 2020

Study: Many COVID-19 patients suffer cardiovascular damage even after recovery

One of the most harrowing effects of COVID-19 is severe damage to the lungs, which makes breathing hard or impossible for those who're severely affected.

21 Aug 2020

SARS-CoV-2 ORF9c responsible for immune evasion and efficient infection of host

A recent study by researchers at the Sanford Burnham Prebys Medical Discovery Institute and the University of California San Francisco and published on the preprint server bioRxiv in August 2020 shows that a protein encoded by the subgenomic sequence ORF9c of SARS-CoV-2 is responsible for the low antiviral response in infected humans, enabling the successful replication of the virus in the host.

21 Aug 2020

New York Blood Center receives $15.6 million NIH grant for sickle cell transfusion research

The National Heart, Lung and Blood Institute of the National Institutes of Health has awarded a five-year grant of $15.6 million to Karina Yazdanbakhsh, PhD, of New York Blood Center’s Lindsley F. Kimball Research Institute, to lead a collaborative research program studying the consequences of transfusions in patients with sickle cell disease and developing strategies to optimize transfusion management for this patient group.

21 Aug 2020

Medical Research News

DNA nanoswitches may provide an inexpensive platform to rapidly detect emerging viruses

New injectable drug could offer long-lasting protection from HIV with fewer side effects

Researchers discover new mechanism for anticancer drug resistance in gastric cancer

COVID-19 patients most likely readmitted to hospital for respiratory distress, study finds

VUMC receives $34 million grant for nationwide convalescent plasma study

CT scans used at a higher rate in children with cognitive impairment to diagnose appendicitis

New test can simplify the measurement of attitudes towards autistic people

Study identifies several new microbes that cause dental caries

Researchers reproduce the pathogenesis of hereditary kidney disease from human iPS cells

Strong feelings of germ aversion and pathogen disgust associated with preventative behavior

Artificial intelligence can help detect heart disease based on facial photos

Women surgeons earn a disproportionate share of NIH research grants

A new mechanism by which microtubule networks instruct neuronal polarity revealed

Adolescents with “elevated" hunger hormone are more likely to develop post-traumatic stress disorder

Dusp8 protein has regulatory effects on hypothalamic insulin sensitivity

Key molecule can be used to assess prognosis of triple negative breast cancer

Concussion can lead to long-term sleep problems, affect quality of life

Study: Many COVID-19 patients suffer cardiovascular damage even after recovery

SARS-CoV-2 ORF9c responsible for immune evasion and efficient infection of host

New York Blood Center receives $15.6 million NIH grant for sickle cell transfusion research

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

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