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Zinc-finger antiviral protein makes SARS-CoV-2 highly susceptible to interferons

By looking into zinc-finger antiviral proteins (ZAP), a new study from Germany and the United Kingdom (UK) and available on the preprint server bioRxiv suggests that zoonotic transmission of a coronavirus with a specific genetic make-up facilitated the pandemic spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but also its sensitivity to interferons.

7 Jun 2020

Lockdown adversities could affect sleep and mental health

Researchers at University College London warn that the adversities people are facing in the UK as a result of lockdown during the coronavirus disease 2019 (COVID-19) pandemic may be causing sleep problems that could affect mental health.

7 Jun 2020

People suffering from rheumatoid arthritis with increased disease activity have high thrombosis risk

People suffering from rheumatoid arthritis with increased disease activity are more often affected by thrombosis.

5 Jun 2020

Study investigates combined effects of cancer therapy and inherited genetics

Scientists at St. Jude Children's Research Hospital are studying the combined effect of cancer treatments and inherited mutations in DNA-repair genes.

5 Jun 2020

Approved drug could help dampen massive immune response associated with severe COVID-19

The drug acalabrutinib, FDA-approved for the treatment of several types of B cell cancers, improved the oxygenation levels and decreased molecular markers of inflammation in a majority of 19 patients hospitalized for the treatment of severe COVID-19, according to a new study by Mark Roschewski and colleagues.

5 Jun 2020

Researchers receive $1.5 million grant to study impact of cannabis use on Indigenous oral health

A multidisciplinary team from the University of Toronto, with experts from the Faculty of Dentistry and the Waakebiness-Bryce Institute for Indigenous Health at the Dalla Lana School of Public Health have been awarded a five year, $1.5 million grant from the Canadian Institutes of Health Research to study the impact of cannabis use on the oral health of Indigenous populations.

5 Jun 2020

Discovery of new killing mechanism could help design improved teixobactin-based drugs

Scientists at the University of Liverpool and University of Utrecht have taken another step forward on their quest to develop a viable drug based on teixobactin - a new class of potent natural antibiotic capable of killing superbugs.

5 Jun 2020

George Mason researcher examining the use of Brilacidin for treatment of coronavirus infections

Aarthi Narayanan, Assistant Professor, National Center for Biodefense and Infectious Diseases, received $35,000 from Innovation Pharmaceuticals, Inc., for a project in which she is examining the use of Brilacidin for the treatment of coronavirus infections.

5 Jun 2020

Creating hair-bearing human skin becomes a reality

For more than 40 years, scientists and commercial companies have been recreating human skin in laboratories around the world. Yet all of these products lack important aspects of normal skin--hair, nerves, and fat.

5 Jun 2020

Bystander CPR benefits outweigh the risks of COVID-19 infection

Analysis of Seattle emergency medical services and hospital data from January 1 to April 15, 2020, indicates bystander CPR is a lifesaving endeavor whose benefits outweigh the risks of COVID-19 infection, according to a new article published yesterday in the American Heart Association's flagship journal Circulation.

5 Jun 2020

UTHSC researchers receive NIH award for opioid addiction studies

A team of University of Tennessee Health Science Center researchers in the College of Medicine recently received a National Institutes of Health award to study how genetic differences may explain why some people are more susceptible to opioid addiction than others.

5 Jun 2020

Novel disease may lead to a better understanding of cystic fibrosis

Cystic fibrosis is the most frequent severe inherited disorder worldwide. Every year, hundreds of families are confronted with this diagnosis - and to date, there is no cure for this disease that mainly affects the respiratory system.

5 Jun 2020

New educational program improves bike helmet use by urban children

To reduce the number of traumatic brain injuries in children, a team of health care professionals at the Johns Hopkins University School of Medicine and the Johns Hopkins Bloomberg School of Public Health is urging emergency room physicians to help ensure that youngsters are thoroughly educated on the proper use of bike helmets, especially in urban environments where most severe head injuries occur.

5 Jun 2020

NMDA receptors play key role in sleep deficits that accompany psychiatric disorders

Sofya Kulikova, a researcher at HSE University in Perm, is part of an international research team that has discovered potential mechanisms that explain the sleep spindle deficit in electroencephalograms (EEG) of people with schizophrenia. The article was published in the Schizophrenia Research on June 5.

5 Jun 2020

GMU researchers studying effect of cannabidiol on exosome release

Fatah Kashanchi, Professor, Laboratory of Molecular Virology, School of Systems Biology, and Lance Liotta, Co-Director, Applied Proteomics and Molecular Medicine, are working to mitigate virally driven HIV pathenogenesis in the central nervous system.

5 Jun 2020

Sleep fragmentation associated with inflammation and atherosclerosis

Disrupted nightly sleep and clogged arteries tend to sneak up on us as we age. And while both disorders may seem unrelated, a new study from the University of California, Berkeley, helps explain why they are, in fact, pathologically intertwined.

5 Jun 2020

New research expands wearable brain scanner technology for whole head imaging

Scientists from the University of Nottingham developed an initial prototype of a new generation of brain scanner in 2018 which is a lightweight device that can be worn on the head like a hat, and can scan the brain even whilst a patient moves.

5 Jun 2020

Newer data confirms survival advantages, but also side effects for ribociclib in breast cancer

In 2017 and 2019, the German Institute for Quality and Efficiency in Health Care had already examined the advantages and disadvantages of ribociclib in combination with an aromatase inhibitor or fulvestrant in comparison with the appropriate comparator therapy in patients after menopause, with hormone receptor-positive, HER2-negative, locally advanced or metastatic breast cancer.

5 Jun 2020

Researchers recommend TEG test to identify undetected blood clots in COVID-19 ICU patients

Researchers at Baylor College of Medicine are recommending that all COVID-19 patients admitted to the ICU undergo a thromboelastography to test for the risk of forming blood clots.

5 Jun 2020

Study shows how psychedelic drug psilocybin works in the brain

Perhaps no region of the brain is more fittingly named than the claustrum, taken from the Latin word for "hidden or shut away."

5 Jun 2020

Medical Research News

Zinc-finger antiviral protein makes SARS-CoV-2 highly susceptible to interferons

Lockdown adversities could affect sleep and mental health

People suffering from rheumatoid arthritis with increased disease activity have high thrombosis risk

Study investigates combined effects of cancer therapy and inherited genetics

Approved drug could help dampen massive immune response associated with severe COVID-19

Researchers receive $1.5 million grant to study impact of cannabis use on Indigenous oral health

Discovery of new killing mechanism could help design improved teixobactin-based drugs

George Mason researcher examining the use of Brilacidin for treatment of coronavirus infections

Creating hair-bearing human skin becomes a reality

Bystander CPR benefits outweigh the risks of COVID-19 infection

UTHSC researchers receive NIH award for opioid addiction studies

Novel disease may lead to a better understanding of cystic fibrosis

New educational program improves bike helmet use by urban children

NMDA receptors play key role in sleep deficits that accompany psychiatric disorders

GMU researchers studying effect of cannabidiol on exosome release

Sleep fragmentation associated with inflammation and atherosclerosis

New research expands wearable brain scanner technology for whole head imaging

Newer data confirms survival advantages, but also side effects for ribociclib in breast cancer

Researchers recommend TEG test to identify undetected blood clots in COVID-19 ICU patients

Study shows how psychedelic drug psilocybin works in the brain

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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