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Advancing CAR T-cell therapy for treatment of solid tumors

The full title of the research is "The study of the mechanisms of effectiveness of T-cells CAR-T towards solid tumors"; it was supported by nonprofit RakFond (Cancer Fund) and CyStoreLab (a resident of Skolkovo).

25 Mar 2020

Overexpression of hPCL3S could contribute to tumor progression in prostate cancer

The cover for issue 12 of Oncotarget features Figure 11, "Global analyses of the RNA-Seq data of LNCaP empty vector and LNCaP cells overexpressing hPCL3S (Clone 12)" by Abdelfettah, et al.

25 Mar 2020

Excessive salt intake weakens the immune system

A high-salt diet is not only bad for one's blood pressure, but also for the immune system. This is the conclusion of a current study under the leadership of the University Hospital Bonn.

25 Mar 2020

Estimating the number of people exposed to health risks of poor sanitation

Experts are investigating a better way of measuring the number of people exposed to the health risks of poorly-managed sanitation systems - and it will help reveal whether the world is on track to deliver UN Sustainable Goal 6.

25 Mar 2020

Diet, nutrition have profound impact on microbial composition in the gut

Nutrition and diet have a profound impact on microbial composition in the gut, in turn affecting a range of metabolic, hormonal, and neurological processes, according to a literature review by scientists from the George Washington University and the National Institute of Standards and Technology.

25 Mar 2020

Combination produces more proliferative, enduring central memory T cells for cellular therapy

Treating T cells harvested from a patient with a combination of an epigenetic drug and a cytokine while expanding the cells in the lab re-programs them into a stronger T cell type that persists longer than its comrades, researchers at The University of Texas MD Anderson Cancer Center report in Cancer Immunology Research, a journal of the American Association for Cancer Research.

25 Mar 2020

Study contradicts theory that daily aspirin prevents dementia symptoms

Scientists have disproven the theory that taking a low dose of daily aspirin reduces cognitive symptoms of dementia.

25 Mar 2020

Lung cancer medication may have benefits for patients with metastatic brain cancers

A medication commonly used to treat non-small cell lung cancer that has spread, or metastasized, may have benefits for patients with metastatic brain cancers, suggests a new review and analysis led by researchers at St. Michael's Hospital of Unity Health Toronto and Harvard Medical School.

25 Mar 2020

Increase in anxiety, depression and suicidal thinking in US adolescents, survey reports

Data has revealed anxiety, depression, suicidal thoughts, and other "internalizing" problems are rising in American adolescents.

25 Mar 2020

Cancer could potentially be treated with new immunotherapy approach, say researchers

Researchers have made a discovery about EGR4 that could instigate a new immunotherapy approach to treating cancer.

25 Mar 2020

Mother-infant touch and contact promote baby's neurophysiological development

As the world prioritizes social distancing to stop or slow down the spread of coronavirus (COVID-19), a new study by researchers at Florida Atlantic University demonstrates that mother-infant touch and contact are essential for optimal neurodevelopmental regulation in early infancy.

25 Mar 2020

Presence of certain gut bacterium in mothers could protect babies from food allergies

Researchers have found that bacteria in a mother’s gut during pregnancy can protect the baby from developing food allergies.

25 Mar 2020

Study identifies brake on immune activity raising new possibilities for anticancer therapy

The immune system is like a carefully regulated machine, complete with its own built-in "brakes" that prevent it from overreacting and causing excess inflammation in otherwise healthy tissues.

25 Mar 2020

Research shows how stress restructures the brain

Stress restructures the brain by halting the production of crucial ion channel proteins, according to research in mice recently published in JNeurosci.

25 Mar 2020

Women 10% more likely than men to feel unsafe on metro trains and buses

The study, conducted by Imperial College London on data from 2009 to 2018, looked at a third of a million passenger responses to Customer Satisfaction Surveys from 28 cities across four continents.

25 Mar 2020

Video consultations with GPs could help maintain continuity of care during social distancing

Patients and general practice staff are receptive to greater use of video consultations in general practice, however concerns about accessibility and technical challenges have been an obstacle to the technology being widely adopted, a University of Warwick study has found.

25 Mar 2020

Novel imaging technique sheds light on Alzheimer's disease

To understand what happens in the brain when Alzheimer's disease develops, researchers need to be able to study the molecular structures in the neurons affected by Alzheimer's disease.

25 Mar 2020

Researchers uncover molecular link between trans fats and variety of disorders

Tohoku University researchers in Japan have uncovered a molecular link between some trans fats and a variety of disorders, including cardiovascular and neurodegenerative diseases.

25 Mar 2020

YAP signal pathway plays a vital role in the onset of head-and-neck cancer

Joint research between Kobe University and National Hospital Organization Kyushu Cancer Center has revealed that mice with mutations in the YAP signal pathway develop head-and-neck cancer over an extremely short period of time (world's fastest cancer onset mouse model), indicating that this pathway plays a crucial role in the onset of these cancers.

25 Mar 2020

Social distancing could stop coronavirus in just 13 weeks

The coronavirus disease (COVID-19) global pandemic has rippled across the world, with nearly 423,000 people now infected. Many countries have imposed lockdowns and strict quarantine measures to prevent the spread of the deadly virus.

25 Mar 2020

Medical Research News

Advancing CAR T-cell therapy for treatment of solid tumors

Overexpression of hPCL3S could contribute to tumor progression in prostate cancer

Excessive salt intake weakens the immune system

Estimating the number of people exposed to health risks of poor sanitation

Diet, nutrition have profound impact on microbial composition in the gut

Combination produces more proliferative, enduring central memory T cells for cellular therapy

Study contradicts theory that daily aspirin prevents dementia symptoms

Lung cancer medication may have benefits for patients with metastatic brain cancers

Increase in anxiety, depression and suicidal thinking in US adolescents, survey reports

Cancer could potentially be treated with new immunotherapy approach, say researchers

Mother-infant touch and contact promote baby's neurophysiological development

Presence of certain gut bacterium in mothers could protect babies from food allergies

Study identifies brake on immune activity raising new possibilities for anticancer therapy

Research shows how stress restructures the brain

Women 10% more likely than men to feel unsafe on metro trains and buses

Video consultations with GPs could help maintain continuity of care during social distancing

Novel imaging technique sheds light on Alzheimer's disease

Researchers uncover molecular link between trans fats and variety of disorders

YAP signal pathway plays a vital role in the onset of head-and-neck cancer

Social distancing could stop coronavirus in just 13 weeks

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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