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Siah2 Gene Control could Help Treat Melanomas More Effectively

To develop improved cancer immunotherapies, it is essential to understand how cancers shut down the natural immune response to foreign antigens. This current study demonstrates how mice lacking the Siah2 gene, fail to develop BRAF-mutation carrying melanoma from the corresponding cells, completely rejecting them. This could help in boosting the anticancer effect of existing specific immune checkpoint inhibitors, such as anti-PD-1 drugs.

10 Jan 2020

Rejuvenating the BCG Vaccine

A new primate study published in the journal Nature in January 2020, reports that the almost century-old BCG vaccine against tuberculosis, may be used differently to achieve better protection against lung tuberculosis. While more work remains to be carried out before the findings can be accepted as the basis for clinical practice, they are extremely promising in the fight against this killer.

10 Jan 2020

Contaminating Fake Rubber Hand Aids People to Overcome Obsessive-Compulsive Disorder (OCD)

Obsessive-compulsive disorder (OCD) is a mental health condition wherein people are caught in a cycle of obsessions. The rubber hand illusion therapy, whereby fake rubber hands are contaminated with feces, maybe the key in helping people overcome their fears of touching contaminated surfaces, a new study suggests.

10 Jan 2020

Researchers develop new approach to better understand protein interaction in the body

Proteins are often called the working molecules of the human body. A typical body has more than 20,000 different types of proteins, each of which are involved in many functions essential to human life.

10 Jan 2020

Study sheds new light on impact of common plasticizer on human reproductive health

Researchers at Harvard Medical School and the New York State Department of Health have discovered how a common plasticizer associated with human reproductive abnormalities likely does its damage at the molecular level.

10 Jan 2020

Sadness often increases people's craving to smoke, shows study

What drives a person to smoke cigarettes - and keeps one out of six U.S. adults addicted to tobacco use, at a cost of 480,000 premature deaths each year despite decades of anti-smoking campaigns?

9 Jan 2020

Mohamad Khazaei receives SCTM’s Young Investigator Award

Mohamad Khazaei, Ph.D., scientific associate in Dr. Michael Fehlings' lab at Krembil Research Institute, Toronto, is the latest recipient of STEM CELLS Translational Medicine's (SCTM) Young Investigator Award.

9 Jan 2020

University of Kentucky receives $3 million for opioid-related research in criminal justice setting

The University of Kentucky recently received $3 million from the National Institute on Drug Abuse and National Institute on General Medical Sciences to fund new opioid-related research in the criminal justice system.

9 Jan 2020

Study shows how baby and adult brains interact during natural play

Have you ever played with a baby and felt a sense of connection, even though they couldn't yet talk to you? New research suggests that you might quite literally be "on the same wavelength," experiencing similar brain activity in the same brain regions.

9 Jan 2020

Non-fibrillating form of human insulin could improve treatment for diabetes patients

In a promising discovery that could improve the clinical delivery of insulin for people living with diabetes, scientists have developed a non-fibrillating form of human insulin.

9 Jan 2020

Sodium chloride nanoparticles offer potential for cancer therapies with fewer side effects

A new study at the University of Georgia has found a way to attack cancer cells that is potentially less harmful to the patient. Sodium chloride nanoparticles – more commonly known as salt – are toxic to cancer cells and offer the potential for therapies that have fewer negative side effects than current treatments.

9 Jan 2020

Study provides new insights into experience of women with rare neurological disorder

Imagine living with unwanted sexual arousals, occurring unexpectedly and repeatedly, unrelated to any sexual desire or pleasure.

9 Jan 2020

Cardiovascular diseases associated with increased risk of developing kidney failure

New research indicates that cardiovascular diseases- including heart failure, atrial fibrillation, coronary heart disease, and stroke- are each linked with a higher risk of developing kidney failure.

9 Jan 2020

Study examines within-hospital racial and ethnic disparities in severe maternal morbidity rates

Mount Sinai researchers find black and Latina mothers experience higher rates of severe maternal morbidity as compared with white mothers within the same hospital, with insurance status not responsible for these disparities.

9 Jan 2020

Opioid addiction care is harder to access in states considering Medicaid work requirements

Low-income people with addiction, especially those with addiction to opioids, may find it hard to access the kind of care they need to recover no matter where they live, a new study suggests.

9 Jan 2020

Review reveals evidence behind alternative immobilization methods for pediatric patients

As a parent, you want to protect your child from getting hurt; however, avoiding bumps, bruises and broken bones isn't always possible.

9 Jan 2020

Parental enforcement of bedtime yields solid results for sleep-deprived teens

Teenagers in the US simply don't get enough shut eye. The consequences of this epidemic of sleep deprivation are extensive and include increasing rates of anxiety and depression among adolescents, as well as suicidal thoughts and actions.

9 Jan 2020

One-fourth of children with autism miss diagnosis, study finds

One-fourth of children under age 8 with autism spectrum disorder - most of them black or Hispanic - are not being diagnosed, which is critical for improving quality of life.

9 Jan 2020

New closed-loop system provides a way to help individuals with post-bariatric hypoglycemia

Gastric bypass vastly improves the health of the patients who elect to receive the surgery. Post-bariatric hypoglycemia, however, can be a severe complication experienced by 10 to 30 percent of patients.

9 Jan 2020

UMSOM research shows even milder cases of diarrheal diseases can lead to child mortality

Diarrheal diseases are a leading cause of death for young children, accounting for nine percent of all deaths worldwide in children under five years of age, with most occurring in children under two years of age.

9 Jan 2020

Medical Research News

Siah2 Gene Control could Help Treat Melanomas More Effectively

Rejuvenating the BCG Vaccine

Contaminating Fake Rubber Hand Aids People to Overcome Obsessive-Compulsive Disorder (OCD)

Researchers develop new approach to better understand protein interaction in the body

Study sheds new light on impact of common plasticizer on human reproductive health

Sadness often increases people's craving to smoke, shows study

Mohamad Khazaei receives SCTM’s Young Investigator Award

University of Kentucky receives $3 million for opioid-related research in criminal justice setting

Study shows how baby and adult brains interact during natural play

Non-fibrillating form of human insulin could improve treatment for diabetes patients

Sodium chloride nanoparticles offer potential for cancer therapies with fewer side effects

Study provides new insights into experience of women with rare neurological disorder

Cardiovascular diseases associated with increased risk of developing kidney failure

Study examines within-hospital racial and ethnic disparities in severe maternal morbidity rates

Opioid addiction care is harder to access in states considering Medicaid work requirements

Review reveals evidence behind alternative immobilization methods for pediatric patients

Parental enforcement of bedtime yields solid results for sleep-deprived teens

One-fourth of children with autism miss diagnosis, study finds

New closed-loop system provides a way to help individuals with post-bariatric hypoglycemia

UMSOM research shows even milder cases of diarrheal diseases can lead to child mortality

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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