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Fatty acid-binding protein 4 plays an important role in kidney stone formation

Kidney stone disease has a high prevalence worldwide, ranging up to 13% in North America, 9% in Europe, and 5% in Asia. They are painful for patients, often lead to surgery, and impart a significant economic impact.

23 Mar 2020

Underweight patients with diabetes in Singapore have increased risk of TB

"Persistent cough in underweight patients with diabetes warrants screening for active tuberculosis." This is the message in the editorial of the December 2019 issue of the International Journal of Tuberculosis and Lung Disease, based on findings from a Singapore-based study that have reported that patients with diabetes and who were also underweight had an eight-fold increase in their risk of contracting active TB, compared to obese individuals without diabetes.

23 Mar 2020

Study provides better understanding of how dangerous cancer metastases arise

In order to colonize other organs and grow into metastases, tumor cells that detach from the parent tumor need to manipulate their new microenvironment and create a 'metastatic niche'.

23 Mar 2020

Study identifies ancestral fragments of DNA associated with hereditary prostate cancer

Vanderbilt researchers have identified haplotypes, ancestral fragments of DNA, that are associated with hereditary prostate cancer (HPC) in a first-of-its-kind genomic study made possible by the study of prostate cancer patients with family histories of the disease.

23 Mar 2020

Using cannabinoids for management of acute pain

A new systematic review and meta-analysis showed a small but significant reduction in subjective pain scores for cannabinoid treatment compared to placebo in patients experiencing acute pain.

23 Mar 2020

CAR macrophages can be used to effectively fight solid tumors

Chimeric antigen receptor (CAR) T cell therapy has been a game-changer for blood cancers but has faced challenges in targeting solid tumors.

23 Mar 2020

Graphite nanoplatelets on medical devices can prevent infections

Graphite nanoplatelets integrated into plastic medical surfaces can prevent infections, killing 99.99 per cent of bacteria which try to attach - a cheap and viable potential solution to a problem which affects millions, costs huge amounts of time and money, and accelerates antibiotic resistance.

23 Mar 2020

Melinjo seed extract may improve obesity and diabetes

In Southeast Asia, the fruit, flowers, and leaves of Indonesia's "Melinjo" tree are traditional foods.

23 Mar 2020

High blood pressure and obesity shown to be two strongest risk factors for shortening lifespan

A team have demonstrated that high blood pressure and obesity are the two strongest risk factors of shortening our lifespan.

23 Mar 2020

AI could enhance prediction of treatment response among patients with non-small cell lung cancer

Artificial intelligence deep learning algorithms may predict response to systemic treatment for non-small cell lung cancer.

23 Mar 2020

Patients treated with ACEIs and ARBs may be at increased risk of severe COVID-19

James Diaz, MD, MHA, MPH & TM, Dr PH, Professor and Head of Environmental Health Sciences at LSU Health New Orleans School of Public Health, has proposed a possible explanation for the severe lung complications being seen in some people diagnosed with COVID-19.

23 Mar 2020

Tiny device can rapidly detect harmful bacteria in blood

Engineers have created a tiny device that can rapidly detect harmful bacteria in blood, allowing health care professionals to pinpoint the cause of potentially deadly infections and fight them with drugs.

23 Mar 2020

Cumulative doses of oral steroids associated with increased hypertension

Cumulative doses of oral steroids in patients with chronic inflammatory diseases are associated with increased hypertension (blood pressure) for those who take them regularly, found new research in CMAJ.

23 Mar 2020

Research reveals rising rates of liver cancer

New research reveals rising rates of liver cancer around the world, despite advances aimed at preventing the disease. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer Society.

23 Mar 2020

Research may help older adults maintain skeletal muscle mass and physical function for longer

Drug therapies that help older adults maintain their skeletal muscle mass and physical function for longer could be a step closer after researchers at the University of Birmingham identify a key mechanism that drives the clearance of damaged mitochondria.

22 Mar 2020

University of Queensland race to accelerate COVID-19 vaccine research

A funding injection of up to $17 million for vital University of Queensland research could help cut the timeline for an effective vaccine for COVID-19 by six months.

22 Mar 2020

New data shows Wuhan COVID-19 fatality rate 1.4 percent, lower than other countries

It is now abundantly clear that COVID-19 is not "just the flu" as Italy grapples to contain the virus. The country has taken surpassed the death toll of China since it recorded 5,476 deaths with a fatality rate of 8.3 percent. China has first shown a fatality rate of 2 to 3.4 percent, but a new study shows that the rate is lower than previously known.

22 Mar 2020

Using 'young NK cells' could improve the effectiveness of immunotherapy for cancer patients

Immunotherapy that involves treating cancer with the body's own immune cells, or those of a matched donor, shows promise in clinical trials for some patients, but not all.

22 Mar 2020

Newly discovered molecule in the lymphatic system could play a role in autoimmune diseases

A study by investigators at Hospital for Special Surgery has discovered a molecule in the lymphatic system that has the potential to play a role in autoimmune disease.

22 Mar 2020

Autism rates reducing among wealthy whites, while ticking up among poor, ethnic minorities

Wealthy, white California counties--once considered the nation's hotbeds for autism spectrum disorder (ASD)--have seen prevalence flatten or fall in the last two decades, while rates among poor whites and minorities keep ticking up, new CU Boulder research has found.

22 Mar 2020

Medical Research News

Fatty acid-binding protein 4 plays an important role in kidney stone formation

Underweight patients with diabetes in Singapore have increased risk of TB

Study provides better understanding of how dangerous cancer metastases arise

Study identifies ancestral fragments of DNA associated with hereditary prostate cancer

Using cannabinoids for management of acute pain

CAR macrophages can be used to effectively fight solid tumors

Graphite nanoplatelets on medical devices can prevent infections

Melinjo seed extract may improve obesity and diabetes

High blood pressure and obesity shown to be two strongest risk factors for shortening lifespan

AI could enhance prediction of treatment response among patients with non-small cell lung cancer

Patients treated with ACEIs and ARBs may be at increased risk of severe COVID-19

Tiny device can rapidly detect harmful bacteria in blood

Cumulative doses of oral steroids associated with increased hypertension

Research reveals rising rates of liver cancer

Research may help older adults maintain skeletal muscle mass and physical function for longer

University of Queensland race to accelerate COVID-19 vaccine research

New data shows Wuhan COVID-19 fatality rate 1.4 percent, lower than other countries

Using 'young NK cells' could improve the effectiveness of immunotherapy for cancer patients

Newly discovered molecule in the lymphatic system could play a role in autoimmune diseases

Autism rates reducing among wealthy whites, while ticking up among poor, ethnic minorities

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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