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Links between most human diseases and genetics are shaky at best

In most cases, your genes have less than five per cent to do with your risk of developing a particular disease, according to new research by University of Alberta scientists.

20 Dec 2019

Data results of NCI-MATCH trial in tumors with DNA mismatch repair deficiencies

Final results are published from an evaluation of 42 patients treated with the immune checkpoint inhibitor nivolumab in the large multi-arm precision medicine trial, NCI-Molecular Analysis for Therapy Choice (NCI-MATCH or EAY131).

20 Dec 2019

The brain’s temporal lobe is also an attention controlling area, shows study

As you read this line, you're bringing each word into clear view for a brief moment while blurring out the rest, perhaps even ignoring the roar of a leaf blower outside.

19 Dec 2019

Scientists explain how a common virus causes havoc on bone marrow, organ transplant patients

For the first time, scientists have discovered the molecular mechanism behind how a common virus can wreak havoc on bone marrow and organ transplant patients, according to a paper published in the journal Cell & Host Microbe.

19 Dec 2019

Common immune cell linked to failure of checkpoint inhibitors in lung cancer patients

For many lung cancer patients, the best treatment options involve checkpoint inhibitors. These drugs unleash a patient's immune system against their disease and can yield dramatic results, even in advanced cancers.

19 Dec 2019

Canadian First Nations communities with greater social support, trust have lower cardiac risk factors

A major study has found that Canadian First Nations communities with greater socio-economic advantages, educational opportunities, social support of family members and greater trust between community members, have lower cardiac risk factors.

19 Dec 2019

Researchers examine safety-net care for patients initiating maintenance dialysis in the U.S.

New research indicates that non-profit/independently-owned and hospital-based dialysis facilities care disproportionately for uninsured patients with kidney failure and those who quality only for Medicaid. The findings appear in an upcoming issue of JASN.

19 Dec 2019

Study finds differences in dialysis mortality for racial/ethnic groups in U.S. territories and states

A recent analysis found differences in mortality rates for various racial/ethnic groups among patients undergoing dialysis in the U.S. territories vs. the 50 U.S. states. The findings, which appear in an upcoming issue of CJASN, point to the need for research into the causes of these disparities.

19 Dec 2019

Fibroblasts involved in healing wounds play a devastating role in breast cancer development

The connective tissue cells known as fibroblasts are vitally important for our recovery from injury. Sensing tissue damage, they gravitate to the site of a wound, instigating an inflammatory response that mends damaged tissue.

19 Dec 2019

Novel 'tooth-on-a-chip' could open door to personalized dental care

A so-called "tooth-on-a-chip" could one day enable more personalized dentistry, giving dentists the ability to identify dental filling materials that work better and last longer based on a patient's own teeth and oral microbiome.

19 Dec 2019

Penn researchers use MRI scans to predict 10-year breast cancer recurrence

Diverse diseases like breast cancer can present challenges for clinicians, specifically on a cellular level. While one patient's tumor may differ from another's, the cells within the tumor of a single patient can also vary greatly.

19 Dec 2019

Artistic interest lengthens the lifespan

Go ahead, plan those trips to the museum or a concert, to feed your longing for beauty and art. Not only will it give you a few hours of delight, it could contribute to a longer life. This is the striking conclusion reached by a study on older adults, published in December 2019 in the British Medical Journal.

19 Dec 2019

Birth season and heart disease risk – an association?

A new study published in the British Medical Journal December 2019 suggests a novel risk factor for heart disease – the season in which the individual is born. The large study carried out in the US shows that people born in either spring or summer had a significant, though slight, increase in the risk of fatal heart disease, when compared to the autumn-born. Why this should be so is unknown as of now.

19 Dec 2019

Nanopores – the key to identifying amino acids in proteins

DNA and RNA sequencing has become the new watchword for the biological researchers, as this tells them exactly what is going on at cellular level in health and disease. However, it is a partial revelation unless we also know what is happening at the level of proteins as well.

19 Dec 2019

New antibody shows promise in active lupus

A new trial involving the use of an antibody called anifrolumab reports improvement in patients with systemic lupus erythematosus (SLE) after 52 weeks of treatment. The research, titled 'Trial of Anifrolumab in Active Systemic Lupus Erythematosus', is published in the New England Journal of Medicine.

19 Dec 2019

Antiretroviral regimens prescribed to many pregnant women with HIV do not meet federal guidelines

More than 20% of pregnant women beginning anti-HIV treatment were prescribed an antiretroviral treatment that did not meet federal guidelines for use during pregnancy, according to an analysis funded by the National Institutes of Health.

19 Dec 2019

People with peanut allergies avoid tree nuts despite being non-allergic to them

A new study reveals that 4 in 10 people who have peanut allergies choose not to consume tree nuts, despite not having allergies to these nuts. The study titled, “Real world tree nut consumption in peanut-allergic individuals,” was published in Annals of Allergy, Asthma and Immunology in the latest issue. The journal is the scientific journal of the American College of Allergy, Asthma and Immunology (ACAAI).

19 Dec 2019

People living in the southern Peruvian Amazon exposed to hazardous mercury levels

People living in the southern Peruvian Amazon are being exposed to potentially dangerous levels of mercury due to a combination of their diet and artisanal and small-scale gold mining occurring in their communities, a University at Albany researcher found.

19 Dec 2019

Utah scientists receive NIH grant to study how air pollutants aggravate asthma in children

A multidisciplinary team of University of Utah Health scientists has received a five-year, $3 million grant from the National Institutes of variations in pollutant-sensing genes in the lungs could influence air pollution's effects on children who have asthma.

19 Dec 2019

Treating lipedema with liposuction could benefit women with 'painful fat' disease

Suppose you're a teen or young woman who starts putting on fat, mainly in your legs. Doctors say you're obese – but no matter how much you diet and exercise, you can't lose the fat. After years of weight gain, pain, and swelling, you're finally diagnosed with lipedema – a common but "enigmatic" disease of the peripheral fat.

19 Dec 2019

Medical Research News

Links between most human diseases and genetics are shaky at best

Data results of NCI-MATCH trial in tumors with DNA mismatch repair deficiencies

The brain’s temporal lobe is also an attention controlling area, shows study

Scientists explain how a common virus causes havoc on bone marrow, organ transplant patients

Common immune cell linked to failure of checkpoint inhibitors in lung cancer patients

Canadian First Nations communities with greater social support, trust have lower cardiac risk factors

Researchers examine safety-net care for patients initiating maintenance dialysis in the U.S.

Study finds differences in dialysis mortality for racial/ethnic groups in U.S. territories and states

Fibroblasts involved in healing wounds play a devastating role in breast cancer development

Novel 'tooth-on-a-chip' could open door to personalized dental care

Penn researchers use MRI scans to predict 10-year breast cancer recurrence

Artistic interest lengthens the lifespan

Birth season and heart disease risk – an association?

Nanopores – the key to identifying amino acids in proteins

New antibody shows promise in active lupus

Antiretroviral regimens prescribed to many pregnant women with HIV do not meet federal guidelines

People with peanut allergies avoid tree nuts despite being non-allergic to them

People living in the southern Peruvian Amazon exposed to hazardous mercury levels

Utah scientists receive NIH grant to study how air pollutants aggravate asthma in children

Treating lipedema with liposuction could benefit women with 'painful fat' disease

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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