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Smokers at increased risk of severe COVID-19 according to a large population study

A new UK study available on the preprint server medRxiv screened 2.4 million users of a symptom reporting application during the coronavirus disease (COVID-19) pandemic, revealing that smokers are at higher risk of increased symptom burden and more prone to hospitalization.

24 May 2020

Study brings surgeons one step closer to helping babies with Hirschsprung's disease

Babies with Hirschsprung's disease are born with an incomplete or absent gut nervous system. Children's Hospital Los Angeles investigator Tracy Grikscheit, MD, runs a laboratory that investigates the therapeutic potential of tissue engineering - the induced growth of healthy tissue using stem cells.

22 May 2020

Kidney transplants: Volume of services correlated with quality of treatment outcomes

In complex operations, is there a correlation between the volume of service provided per hospital and the quality of the treatment outcome? This question is addressed in eight commissions on minimum volumes that the Federal Joint Committee has issued to the Institute for Quality and Efficiency in Health Care.

22 May 2020

Study presents the first automatic method to detect and segment intrauterine cavity

Twin-to-twin transfusion syndrome (TTTS) occurs in around 10-15% of pregnancies with twins that share the same placenta.

22 May 2020

Blood test could help doctors identify patients at risk of developing type 2 diabetes

Scientists have identified metabolites in the blood that accurately predict whether a woman will develop type 2 diabetes after experiencing a transient form of illness during pregnancy.

22 May 2020

High pre-pregnancy glucose levels linked to adverse outcomes even in non-diabetic women

An elevated pre-pregnancy hemoglobin A1c--which measures average blood glucose concentration--is associated with a higher risk of adverse pregnancy outcomes even in women without known diabetes, according to a new study published this week in PLOS Medicine by Joel Ray of ICES and the University of Toronto, Canada, and colleagues.

22 May 2020

Understanding mechanism behind antibiotic-resistant gonorrhea sets stage for new treatments

Due to the spread of antibiotic-resistant strains of Neisseria gonorrhoeae, existing treatments for gonorrhea, the sexually transmitted infection caused by the bacterium, are no longer effective. In the absence of a vaccine, there is an urgent need to develop novel treatment options.

22 May 2020

Women and older adults still vastly underrepresented in cholesterol drug trials

Although heart disease is the leading cause of death in women, and older adults are more likely to have heart and vascular disease than young people, randomized clinical trials testing medications to lower cholesterol have historically underenrolled both groups.

22 May 2020

Researchers examine quality measures for medical care of homebound older adults

There are an estimated 2 million older adults who are homebound or unable to leave their homes due to multiple chronic conditions and functional impairment.

22 May 2020

Study finds evidence of injury in placentas from COVID-19-positive pregnant women

The placentas from 16 women who tested positive for COVID-19 while pregnant showed evidence of injury, according to pathological exams completed directly following birth, reports a new Northwestern Medicine study.

22 May 2020

Blanket prescription of do-not-resuscitate orders in COVID-19 patients may be unwarranted

It's inappropriate to consider blanket do-not-resuscitate orders for COVID-19 patients because adequate data is not yet available on U.S. survival rates for in-hospital resuscitation of COVID-19 patients and data from China may not relate to U.S. patients, according to a new article published today in Circulation: Cardiovascular Quality and Outcomes, an American Heart Association journal.

22 May 2020

Supportive care for reducing fatigue may not be sufficiently adhered to by breast cancer patients

Cancer-related fatigue is a prevalent and potentially persistent issue among breast cancer survivors, which can prevent them from returning to their previous life well after treatment ends and they are declared free of disease.

22 May 2020

Americans with limited birth control access more likely to turn to the internet for abortion information

Residents of states with limited access to contraceptives and high rates of unplanned pregnancies are more likely to turn to the internet for information about abortion. These are the findings of a new study of Google search data across all 50 states by researchers at the University of California, Berkeley.

22 May 2020

Platinum-based chemotherapy may improve outcomes for some metastatic pancreatic cancer patients

Patients with metastatic pancreatic cancer who had germline or somatic mutations in DNA repair genes had better clinical outcomes after platinum-based chemotherapy, as compared with patients without these mutations.

22 May 2020

Novel biomarkers linked to improved outcomes with immunotherapy in metastatic breast cancer

Two novel biomarkers have been found to correlate with improved outcomes with immunotherapy in metastatic breast cancer and may help to identify the patients most likely to benefit from this treatment, according to exploratory studies reported at the ESMO Breast Cancer Virtual Meeting 2020.

22 May 2020

Study identifies risk factors for severe COVID-19 or death in the UK

Age, male sex, obesity, and underlying illness have emerged as risk factors for severe covid-19 or death in the UK, according to the largest cohort study to date published by The BMJ today.

22 May 2020

A clinical decision support system to help identify adverse health events in trauma patients

Chinese researchers from The Trauma Center of Peking University People's Hospital and National Institute of Health Data Science at Peking University are using big data to help identify trauma patients who could experience potential adverse health events in the emergency department through the aid of a clinical decision support system.

22 May 2020

Medical Research News

Smokers at increased risk of severe COVID-19 according to a large population study

Study brings surgeons one step closer to helping babies with Hirschsprung's disease

Kidney transplants: Volume of services correlated with quality of treatment outcomes

Study presents the first automatic method to detect and segment intrauterine cavity

Blood test could help doctors identify patients at risk of developing type 2 diabetes

High pre-pregnancy glucose levels linked to adverse outcomes even in non-diabetic women

Understanding mechanism behind antibiotic-resistant gonorrhea sets stage for new treatments

Women and older adults still vastly underrepresented in cholesterol drug trials

Researchers examine quality measures for medical care of homebound older adults

Study finds evidence of injury in placentas from COVID-19-positive pregnant women

Blanket prescription of do-not-resuscitate orders in COVID-19 patients may be unwarranted

Supportive care for reducing fatigue may not be sufficiently adhered to by breast cancer patients

Americans with limited birth control access more likely to turn to the internet for abortion information

Platinum-based chemotherapy may improve outcomes for some metastatic pancreatic cancer patients

Novel biomarkers linked to improved outcomes with immunotherapy in metastatic breast cancer

Study identifies risk factors for severe COVID-19 or death in the UK

A clinical decision support system to help identify adverse health events in trauma patients

Internet-delivered treatment to help young people tackle worry and overthinking

Study shows impact of childhood adversity on neuropsychological functioning in adulthood

Scientists identify key cell signaling pathway that drives muscle loss

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

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