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Moffitt researchers develop efficient method for creating mouse models to study melanoma

Genetically engineered mouse models are often used by scientists to study how the addition, deletion or mutation of genes affects the development of disease and effects of drugs.

17 Dec 2019

Cancer drug shows promise in battling Parkinson’s disease

Parkinson’s disease (PD) is a lifelong condition that affects the nerve cells in the brain that produce dopamine. As a result, people with this neurodegenerative disease experience tremors, changes in speech, gait issues, and muscle rigidity. Though it has no cure, a new drug used to treat cancer shows promise in treating Parkinson’s.

17 Dec 2019

Leukemia patients treated with common cancer drug have heightened risk of heart failure

Patients with acute lymphoblastic leukemia or acute myeloid leukemia who are treated with anthracyclines are at a heightened risk of heart failure- most often within one year of exposure to the chemotherapy treatment, according to a new study led by researchers at Penn Medicine.

17 Dec 2019

New autism guidelines target early detection

Pediatricians should initiate treatment of children showing signs of autism spectrum disorder (ASD) even before tests confirm a diagnosis, the newest recommendations from the American Academy of Pediatrics reports.

17 Dec 2019

Pilot study shows strong results for genicular artery embolization to treat OA-related knee pain

A new study published in Journal of Vascular and Interventional Radiology details the first study of its kind in the U.S. to examine the use of genicular artery embolization (GAE) for extended treatment of knee pain caused by osteoarthritis.

17 Dec 2019

MGH scientists use electronic health records for early diagnosis of dementia

A team of scientists from Massachusetts General Hospital has developed a software-based method of scanning electronic health records to estimate the risk that a healthy person will receive a dementia diagnosis in the future.

17 Dec 2019

Immune cells may link body composition to how cognition changes with age, study suggests

Iowa State researchers have found for the first time that less muscle and more body fat may affect our thinking as we age, and changes in parts of the immune system could be responsible.

17 Dec 2019

Scientists reveal brain mechanisms and functional regions that underlie confirmation bias

An international research team comprising neuroscientists at Virginia Tech, University College London and the University of London revealed brain mechanisms and functional regions that underlie confirmation bias -- a phenomenon where people strongly favor information that reinforces their existing opinions over contradictory ones.

17 Dec 2019

Targeting specific nuclear transport systems may lead to possible therapeutic strategies for cancer

Although less often the focus of cancer research, recent studies have hinted at the possible importance of a type of protein known as nuclear transport receptors.

17 Dec 2019

Study shows how immune cells quickly switch to attack mode

Macrophages have two faces: In healthy tissue, they perform important tasks and support their environment. However during an infection, they stop this work and hunt down the pathogens instead.

17 Dec 2019

Study finds new drivers of destructive inflammation

Scientists describe in Nature Immunology an entirely new molecular process in mice that triggers T cell-driven inflammation and causes different auto-immune diseases.

17 Dec 2019

Combination of two antibiotics eradicates latent tuberculosis in macaques

A major goal of tuberculosis (TB) research is to find a way to treat people with the latent (or inactive) form of the disease to keep them from developing symptomatic TB.

17 Dec 2019

Researchers identify protein that is key for successful viral DNA uncoating

Viruses have been part of animals and humans for eons. When viruses invade a cell, they can infiltrate the nucleus with their genome and become part of the genome of the infected organism. Viruses transfer their genes between various organisms, as well as between tissues containing well differentiated cells inside a living creature. But how they uncoat their well-packed genes and release them to cause infection is largely unknown.

17 Dec 2019

Australian researchers find new drug target for preventing the spread of malaria

Australian researchers have found a new drug target for stopping the spread of malaria, after successfully blocking the world's deadliest malaria parasite - Plasmodium falciparum - from completing the 'transmission stage' of its lifecycle.

17 Dec 2019

Contribution of suicide to opioid-related deaths may be overstated, study suggests

The study is the first to use national data on opioid overdose deaths between 2000 and 2017 to find out what share of these deaths in individuals age 15 and older were unintentional, due to suicide, or of undetermined intent.

17 Dec 2019

Study shows the effect of obesity on routine blood tests in children

Weight may affect doctors' ability to correctly interpret routine blood tests in children, according to new research published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

17 Dec 2019

New discovery can allow scientists to tell old and new memories apart

Researchers have discovered signatures in brain activity that allow them to tell old and new memories apart. A team at Japan's RIKEN Center for Brain Science analyzed recordings from mouse brains using a machine-leaning algorithm, which was able to accurately classify memories as recent or remote. They also found robust communication between a frontal brain region and the hippocampus, an area strongly involved in memory formation.

17 Dec 2019

New technique could lead to better diagnosis and effective tracking of Huntington’s disease

Researchers at the universities of Southampton and Cambridge have developed a new technique to analyze biochemical changes unique to Huntington's disease.

17 Dec 2019

Zebrafish 'avatars' help distinguish radiosensitive from radioresistant tumors

Radiotherapy can effectively reduce or even eliminate some tumors; others, however, show enduring resistance. Considering the potentially harmful side effects of radiotherapy, clinicians agree that it is paramount to be able to determine if a patient will benefit from radiotherapy before exposing them to any of the associated risks.

17 Dec 2019

Women who live near green space may be at lower risk of excess weight, obesity

Women who live less than 300 meters from green space may be at lower risk of excess weight or obesity.

17 Dec 2019

Medical Research News

Moffitt researchers develop efficient method for creating mouse models to study melanoma

Cancer drug shows promise in battling Parkinson’s disease

Leukemia patients treated with common cancer drug have heightened risk of heart failure

New autism guidelines target early detection

Pilot study shows strong results for genicular artery embolization to treat OA-related knee pain

MGH scientists use electronic health records for early diagnosis of dementia

Immune cells may link body composition to how cognition changes with age, study suggests

Scientists reveal brain mechanisms and functional regions that underlie confirmation bias

Targeting specific nuclear transport systems may lead to possible therapeutic strategies for cancer

Study shows how immune cells quickly switch to attack mode

Study finds new drivers of destructive inflammation

Combination of two antibiotics eradicates latent tuberculosis in macaques

Researchers identify protein that is key for successful viral DNA uncoating

Australian researchers find new drug target for preventing the spread of malaria

Contribution of suicide to opioid-related deaths may be overstated, study suggests

Study shows the effect of obesity on routine blood tests in children

New discovery can allow scientists to tell old and new memories apart

New technique could lead to better diagnosis and effective tracking of Huntington’s disease

Zebrafish 'avatars' help distinguish radiosensitive from radioresistant tumors

Women who live near green space may be at lower risk of excess weight, obesity

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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