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Circulating ceramide ratios may be useful predictors of future dementia risk

Novel blood-based biomarkers for dementia could identify disease at an early preclinical stage, serve as surrogate outcomes for clinical trials of investigational therapies and even identify future potential therapeutic targets.

13 Feb 2020

Researchers investigate how early life trauma contributes to functional neurological disorder

In individuals with functional neurological disorder, the brain generally appears structurally normal on clinical MRI scans but functions incorrectly (akin to a computer software crashing), resulting in patients experiencing symptoms including limb weakness, tremor, gait abnormalities and non-epileptic seizures.

13 Feb 2020

Targeting one's internal clock could prevent or slow breast cancer progression

City of Hope scientists have identified an unlikely way to potentially prevent or slow the progression of aggressive breast cancer: target one's internal clock.

13 Feb 2020

Autophagy genes work against tumors in some ovarian cancers

Shedding light on a decades-old controversy, scientists at the Medical University of South Carolina and University of California at San Diego published findings in PLOS Genetics this month showing that autophagy or "self-eating" genes work against tumors in certain types of ovarian cancer.

13 Feb 2020

Kisspeptin can boost human attraction brain pathways, study shows

The researchers behind the early-stage work, published in JCI Insight, are exploring whether kisspeptin can ultimately be used to treat men with common psychosexual disorders - sexual problems which are psychological in origin such as low libido.

13 Feb 2020

Researchers develop high-resolution forecast model for the spread of malaria

Climate change aggravates global health problems, above all for people in Africa. The group "Climate change and Health in Sub-Saharan Africa" funded by the German Research Foundation studies climate-induced damage to health in Burkina Faso and Kenya.

13 Feb 2020

Living in greener neighborhoods may delay onset of menopause

Living near green spaces is associated with a wide variety of benefits, including a lower risk of obesity, improved attention capacity in children and slower physical decline in old age.

13 Feb 2020

New grant-funded project works toward improving sleep in pediatric cancer patients

Pediatric cancer patients may soon get a better night's sleep and experience improved comfort levels, thanks to a new grant-funded project led by a Rutgers University-Camden researcher.

13 Feb 2020

Bilingualism can delay symptoms of dementia, study reveals

A study by York University psychology researchers provides new evidence that bilingualism can delay symptoms of dementia.

13 Feb 2020

Moffitt research may provide a path toward improved multi-drug adaptive therapies

Personalized cancer treatments have greatly improved the lives of patients; however, many eventually develop resistance to these targeted drugs.

13 Feb 2020

Health officials may be underestimating the prevalence of teen e-cigarette use

Juul, the popular e-cigarette brand that is being sued for fueling the youth e-cigarette epidemic, may have influenced high school students' perception of vaping such that some Juul users do not consider themselves e-cigarette users, a Rutgers-led study finds.

13 Feb 2020

Understanding stress-induced bladder dysfunction in children

We know that stress can have a profound impact on health. But it's rare to discover a health issue that is caused directly by stress.

13 Feb 2020

Acid reflux drug may be a promising therapy to reduce preterm birth

Lansoprazole, an over-the-counter acid reflux drug that is often taken by pregnant women, may be a promising therapy to reduce preterm birth, according to a computational drug repurposing study that also tested several of the drugs in mice.

13 Feb 2020

A143T variant of the GLA gene likely to cause late-onset Fabry cardiomyopathy

The A143T variant of the GLA gene is associated with an increased risk of Fabry cardiomyopathy, according to a new study.

13 Feb 2020

Surprising discovery about childhood brain tumor may unlock new cancer treatments

A surprising discovery about a rare form of childhood brain cancer suggests a new treatment approach for that cancer and, potentially, many others.

13 Feb 2020

Study highlights trends in hospitalization, outcomes among veterans with critical limb ischemia

Between 2005 and 2014, the number of veterans who were hospitalized, required amputation or died due to critical blockages in leg arteries declined, according to new research published today in Circulation: Cardiovascular Interventions, a journal of the American Heart Association.

13 Feb 2020

Maternal use of cosmetics containing parabens tied to child's future overweight

Parabens are used as preservatives in cosmetics. If pregnant women use cosmetics containing parabens that remain on the skin for protracted periods, this may have consequences for their child's subsequent weight development.

13 Feb 2020

Study tests hypothesis that empty SV40 capsids would improve sepsis outcomes

Numerous previous attempts to develop therapeutic treatments, directed at discreet targets of the sepsis cascade, could not cope with the complex pathophysiology of sepsis and failed.

13 Feb 2020

P53-deficient oral cancers recruit and reprogram nerves to fuel tumor growth

Loss of an important tumor-suppressing gene allows head and neck cancer to spin off signals to nearby nerves, changing their function and recruiting them to the tumor, where they fuel growth and cancer progression, researchers from The University of Texas MD Anderson Cancer Center report in the journal Nature today.

13 Feb 2020

Study finds no evidence of intrauterine vertical transmission of COVID-19 infection

There is currently no evidence that the 2019 novel coronavirus disease (COVID-19) causes severe adverse outcomes in neonates or that it can pass to the child while in the womb, according to a small observational study of women from Wuhan, China, who were in the third trimester of pregnancy and had pneumonia caused by COVID-19.

12 Feb 2020