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Chest infections cause 1 in 7 child deaths

The number of deaths in children due to lower respiratory infections (LRIs) such as pneumonia and influenza has come down considerably. Yet, they still account for the highest number of deaths in children under 5 years of age, at one in seven of all deaths in this age group, according to a detailed study published in the journal The Lancet Infectious Diseases.

31 Oct 2019

Popular health campaigns aren’t always the most productive, says new study

Researchers have found that just because a public health campaign is popular among the digital community, it doesn’t mean it will produce gains in healthy behavior. This study, published in Lancet Oncology, concludes that in addition to attractive slogans or easy-to-understand captions and images, the relevance of the focused health issue to the target audience and to current guidelines may guide audience behavior.

31 Oct 2019

Scientists visualize complex cellular machine to yield new insights in cancer

Cellular machines that control chromosome structure, such as the RSC complex, are mutated in about one-fifth of all human cancers.

31 Oct 2019

Malaria parasite with Quinoline drug investigated in-vivo

Researchers from Israel, in collaboration with others looked at the effects of the malaria plasmodium on red blood cells in vivo in presence of a drug, to understand the workings of the pathogen in its disease causing ability and also lay foundation for development of effective treatment for the deadly disease.

31 Oct 2019

Three UCLA researchers receive multimillion-dollar grant from state's stem cell agency

Three researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have received awards totaling more than $18 million from the California Institute for Regenerative Medicine, the state's stem cell agency.

31 Oct 2019

Tumour conversion of glial cells when exposed to bowel cancer secretions

A new study has shown that glial cells of the gut (part of the enteric nervous system) when exposed to secretions from colon cancer cells are convert into tumours themselves. These altered glial cells then convert into promoters of tumours said the study researchers.

31 Oct 2019

Study shows how measles virus causes immune amnesia

Over the last decade, evidence has mounted that the measles vaccine protects in not one but two ways: Not only does it prevent the well-known acute illness with spots and fever that frequently sends children to the hospital, but it also appears to protect from other infections over the long term.

31 Oct 2019

Increasing anti-tumor activity of compound extracted from an Amazon plant

Researchers in Brazil have prepared modified forms of the alkaloids produced by Uncaria guianensis, a woody vine native to the Amazon Rainforest.

31 Oct 2019

Cerebrospinal fluid washes through the brain in rhythmic waves during sleep

New research from Boston University suggests that tonight while you sleep, something amazing will happen within your brain. Your neurons will go quiet. A few seconds later, blood will flow out of your head.

31 Oct 2019

OHSU receives $2.1 million to develop new vaccine additives for tropical viruses

Sometimes vaccines need a little help to protect people against infectious diseases.

31 Oct 2019

Researchers identify new kidney cancer subtypes and clues to better diagnosis, treatment

In what is believed to be the most comprehensive molecular characterization to date of the most common - and often treatment-resistant - form of kidney cancer, researchers at Johns Hopkins' departments of pathology and oncology, Johns Hopkins Kimmel Cancer Center, and the Johns Hopkins University School of Medicine report evidence for at least three distinct subtypes of clear cell renal cell carcinoma (ccRCC), along with new revelations about the proteins that define them.

From Johns Hopkins Medicine 31 Oct 2019

GLP-1 receptors could serve as targets for novel medications to treat opioid use disorder

Opioid use disorder and overdose deaths are a major public health crisis in the United States. While medication-assisted treatments for opioid use disorder exist, these treatments remain inadequate for many patients, resulting in a high rate of relapse following detoxification.

31 Oct 2019

Molecular gatekeepers that regulate calcium ions vital for muscle health and repair

Calcium ions are essential to how muscles work effectively, playing a starring role in how and when muscles contract, tap energy stores to keep working and self-repair damage.

31 Oct 2019

Researchers discover key mechanism in insulin release by cholesterol metabolite

Insulin which is released by pancreatic beta-cells is the main regulator of blood sugar. Previous and current studies by a research group at Lund University in Sweden have identified around hundred different receptors on the surface of the beta-cells, with a diverse functional impact on the beta-cells.

31 Oct 2019

Discovery has potential to put the brakes on Parkinson's 'runaway train'

Researchers at the University of Dundee have made a discovery they believe has the potential to put the brakes on the 'runaway train' that is Parkinson's disease.

31 Oct 2019

High-intensity workouts improve memory in older adults

Researchers at McMaster University who examine the impact of exercise on the brain have found that high-intensity workouts improve memory in older adults.

31 Oct 2019

Study identifies a kinase as potential target to treat heart failure

An unexplored kinase in heart muscle cells may be a good target to treat heart failure, a disease that is only incrementally delayed by existing therapies.

31 Oct 2019

Screening tool in pediatric ER accurately estimates suicide risk among youth

A suicide risk screening tool that Johns Hopkins Medicine implemented in its pediatric emergency department six years ago appears to provide an accurate gauge of which youth are most vulnerable and has identified more than 2,000 patients who might benefit from mental health treatment and resources, according to a study led by researchers at Johns Hopkins Bloomberg School of Public Health and Johns Hopkins Medicine.

31 Oct 2019

Factor responsible for formation of white blood cells has regulatory effect on adaptive immunity

Granulocyte colony-stimulating factor, which causes division and differentiation of bone marrow cells depending on the body's need for leukocytes, has a significant regulatory effect not only on innate, but also on adaptive immunity.

31 Oct 2019

Common early sign of cardiovascular disease associated with cancer risk

A Mayo Clinic-led study involving 488 cardiac patients whose cases were followed for up to 12 years finds that microvascular endothelial dysfunction, a common early sign of cardiovascular disease, is associated with a greater than twofold risk of cancer.

31 Oct 2019