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Early combination therapy provides long-term benefits for patients with type 2 diabetes

A new study, VERIFY (Vildagliptin Efficacy in combination with metfoRmIn For earlY treatment of type 2 diabetes) presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) in Barcelona, Spain (16-20 Sept, 2019), and published simultaneously in The Lancet, is the first to show that early combination therapy using vildagliptin and metformin in patients newly diagnosed with type 2 diabetes (T2D) leads to better long-term blood sugar control and a reduced rate of treatment failure than metformin alone.

19 Sep 2019

NMDAR receptor is responsible for breast-to-brain metastases, shows study

In 2018, breast cancer was the most common cancer in women worldwide, accounting for about a quarter of all reported cancers. One of the biggest problems with any type of cancer is metastasis; and when breast cancer metastasizes, the brain is a common destination.

19 Sep 2019

Mint-flavored vapes and the trouble with pulegone

Even while the recent outbreak of acute serious lung disease in vapers is challenging the skill and technology of the medical field, a new report published in the journal JAMA Internal Medicine on September 16, 2019, says that a natural plant oil called pulegone, which is used to impart a minty flavor to e-cigarettes, could quite possibly be carcinogenic at the levels found in these devices.

18 Sep 2019

New device uses electromagnetic waves to reverse Alzheimer’s

A new study, to be published in the September 3, 2019, issue of the Journal of Alzheimer's Disease, provides something to cheer about for the estimated 44 million patients who have Alzheimer’s disease (AD) in the US, and their hard-pressed caregivers.

18 Sep 2019

Zylka lab receives NIH grant to advance treatments for neurodevelopmental disorders

The National Institutes of Health have awarded two separate grants totaling $6.1 million to Mark Zylka, PhD, director of the UNC Neuroscience Center. One of the grants was co-awarded to Ben Philpot, PhD, associate director of the center at the UNC School of Medicine.

18 Sep 2019

Embryonic damage due to autoantibodies could be cause of behavioral disorders in the child

Dysfunctions in the maternal immune system that occur during pregnancy could possibly lead to impaired brain development in the unborn child.

18 Sep 2019

More surgeries are scheduled when surgeon is well rested

Researchers at Linköping University have investigated how orthopedic surgeons make decisions regarding surgery, and how the decisions are related to how much of their work shift they have completed.

18 Sep 2019

Brain imaging reveals mechanisms underlying auditory processing in nonverbal children with autism

Even though nonverbal or minimally verbal people who have autism spectrum disorder (ASD) make up between 25 and 30 percent of the total autistic population, almost no studies have been done focusing on this group and their particular needs.

18 Sep 2019

Favorable aspects of childhood experience linked to people living longer

After years of generalized theories and hypothesis, research has finally pinpointed certain aspects of childhood experience linked to people living longer.

18 Sep 2019

New study assesses the prevalence of screening for social needs

A new study from The Dartmouth Institute for Health Policy and Clinical Practice, published this week in JAMA Network Open, finds that most U.S. physician practices and hospitals report screening patients for at least one social need, a trend that is expected to increase in the future, and that practices that care for disadvantaged patients report higher screening rates.

18 Sep 2019

Cannabidiol may alleviate seizures and normalize brain rhythms in Angelman syndrome

A marijuana plant extract, also known as cannabidiol, is being commonly used to improve anxiety, sleep problems, pain, and many other neurological conditions.

18 Sep 2019

Roswell Park moving three-pronged immunotherapy strategy forward with support from DoD grant

A team from Roswell Park Comprehensive Cancer Center is moving a new three-part strategy for treating advanced cancers forward with support from a U.S. Department of Defense grant to Pawel Kalinski, MD, PhD, Vice Chair for Translational Research and Rustum Family Professor for Molecular Therapeutics and Translational Research at the Buffalo, N.Y.-based cancer center.

18 Sep 2019

Psoriasis drug could be repurposed to treat osteosarcoma

A treatment for psoriasis could be repurposed to treat a rare but aggressive form of youth cancer, new findings from the Garvan Institute of Medical Research suggest.

18 Sep 2019

Compound could play a novel role in halting spread of pancreatic cancer

In early test tube and mouse studies, investigators at Johns Hopkins Medicine and the Johns Hopkins Kimmel Cancer Center have found that nonmuscle myosin IIC (MYH14), a protein activated in response to mechanical stress, helps promote metastatic behavior in pancreatic cancer cells, and that the compound 4-hydroxyacetophenone (4-HAP), known to stiffen myosin IIC-containing cells, can send it into overdrive, overwhelming the ability of cells to invade nearby tissue.

18 Sep 2019

Could drinking a small amount of alcohol everyday be good for type 2 diabetes?

A new meta-analysis suggests that people with type 2 diabetes may benefit from light-to-moderate drinking, which could have a positive effect on blood glucose and fat metabolism.

18 Sep 2019

Concerns over GM mosquitoes released in Brazil

A field experiment that released genetically modified mosquitoes in Brazil to control natural populations of the insect may have had unintended consequences.

18 Sep 2019

Alarming number of life-threatening heart infections related to drug abuse

As the nationwide opioid epidemic continues, more young people are developing a life-threatening heart infection that can result from drug abuse.

18 Sep 2019

A vegan diet could boost gut microbes that aid weight loss

Switching to a vegan diet could help people lose nearly one pound in weight every week and significantly reduce their risk for diabetes, say researchers.

18 Sep 2019

Anti-cancer effects of lycopene in tomatoes canceled out by iron-rich foods

Tomatoes have proven cancer-fighting properties, but new research suggests that eating them with iron-rich meats can destroy this effect.

18 Sep 2019

Human sleep rhythm is much older than previously believed, Javan slow loris study reveals

People typically sleep seven to eight hours in one stretch and stay awake for the rest of the day. Evolutionary scientists have assumed that this rhythm of sleep arose when our early ancestors went from being nocturnal to diurnal, but a new study of the Javan slow loris indicates that the human way of sleeping is much older.

18 Sep 2019