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Radiation therapy reduces episodes of deadly rapid heart rhythm

A single high dose of radiation aimed at the heart significantly reduces episodes of a potentially deadly rapid heart rhythm, according to results of a phase one/two study at Washington University School of Medicine in St. Louis.

17 Sep 2019

Scientists pinpoint cause of fatal genetic disorder in children

Scientists at Washington University School of Medicine in St. Louis appear to have solved a decades-long mystery regarding the precise biochemical pathway leading to a fatal genetic disorder in children that results in seizures, developmental regression and death, usually around age 3.

17 Sep 2019

Clinically undetectable Plasmodium relapse infections may still pose a threat

Nonhuman primates with clinically undetectable Plasmodium relapse infections still harbor parasitic gametocytes that may be infectious to mosquitoes, according to a study published September 19 in the open-access journal PLOS Pathogens by F. Eun-Hyung Lee and Mary R. Galinski of Emory University, Tracey J. Lamb of the University of Utah, and colleagues.

From PLOS ONE 17 Sep 2019

Combination therapies can shrink lung tumors in mice and human cancer cells

Combining a new class of drug with two other compounds can significantly shrink lung tumors in mice and human cancer cells, finds a new study led by the Francis Crick Institute and The Institute of Cancer Research, London.

17 Sep 2019

Midwives need more support to deliver advice on alcohol consumption in pregnancy

A new study funded by the Institute of Alcohol Studies – ‘Alcohol guidelines for pregnant women: Barriers and enablers for midwives to deliver advice’ – highlights the inconsistency in official guidance that led to midwives giving different advice on alcohol consumption in pregnancy.

17 Sep 2019

Social isolation in adolescence disrupts brain development, mice study shows

Female mice housed alone during adolescence show atypical development of the prefrontal cortex and resort to habitual behavior in adulthood, according to new research published in eNeuro.

From Society for Neuroscience 17 Sep 2019

Researchers identify potential target for diabetes-associated Alzheimer's disease

Researchers have identified a protein that may contribute to the progression of Alzheimer’s disease pathology in type-2 diabetes, reports a new study of male mice and human brain tissue. The research could have implications for future drug development.

From Society for Neuroscience 17 Sep 2019

Researchers study typhoid genomes of travelers from different parts of the world

Salmonella enterica serovar Typhi causes more than 20 million cases of typhoid fever each year, and disproportionately infects children in low and middle income countries.

From PLOS ONE 17 Sep 2019

Inherited genetic tendency appears to protect people from MRSA infections

An inherited genetic tendency appears to increase the likelihood that a person can successfully fight off antibiotic-resistant staph infections, according to a study led by Duke Health researchers.

17 Sep 2019

At-home blood pressure tests offer added value for African Americans

Cardiologists know that when patients use a blood pressure cuff at home, they have a significant head start on managing their heart health risk. Now, researchers have learned the added value for African Americans.

17 Sep 2019

Chemist explores link between Alzheimer's and copper protein molecules in brain cells

A University of Houston chemist is exploring the link between copper protein molecules in brain cells and neurodegenerative diseases like Alzheimer's.

17 Sep 2019

Research may provide better tools for designing personalized protocols for cancer patients

Diversity – at least among cancer cells – is not a good thing. Now, research from the Weizmann Institute of Science shows that in melanoma, tumors with cells that have differentiated into more diverse subtypes are less likely to be affected by the immune system, thus reducing the chance that immunotherapy will be effective.

17 Sep 2019

Mutated ciliary genes tied to heart valve birth defect

The heart pumps blood throughout the body to provide the needed oxygen and nutrients. In the heart, blood flows to get oxygen from the lungs to deliver to the cells. Some of the most important structures in the heart are the valves, because they prevent the backflow of blood, avoiding the mixture of oxygenated blood with the ones that still need to be oxygenated.

17 Sep 2019

New method developed to address failures in promising anti-cancer drug

Biomedical engineers at Duke University have developed a method to address failures in a promising anti-cancer drug, bringing together tools from genome engineering, protein engineering and biomaterials science to improve the efficacy, accuracy and longevity of certain cancer therapies.

17 Sep 2019

Advanced imaging technology may offer new treatment for cancer

Cancer treatment could be dramatically improved by an invention at the University of Waterloo to precisely locate the edges of tumors during surgery to remove them.

17 Sep 2019

Cure for Rett Syndrome a step closer as scientists successfully reactivate 'back-up’ genes

A team headed by Vincent Pasque at his Lab at KU Leuven alongside researchers from the Jean-Christophe Marine lab and the Edith Heard lab have made a significant step towards developing a treatment for Rett syndrome and other X chromosome linked disorders.

17 Sep 2019