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Defective ATP13A2 gene can lead to Parkinson's disease, shows study

Biomedical scientists at KU Leuven have discovered that a defect in the ATP13A2 gene causes cell death by disrupting the cellular transport of polyamines.

30 Jan 2020

Researchers discover new target for repairing heart after heart attack

Billions of cardiac muscle cells are lost during a heart attack. The human heart cannot replenish these lost cells, so the default mechanism of repair is to form a cardiac scar.

30 Jan 2020

New target protein linked to regulation, movement of tumor-associated macrophages

Developing a therapy to combat cancer remains one of the most difficult challenges in medical research. Cancer owes its notorious identity to the fact that the cancer cells use the host's own immune system to grow and spread, ultimately becoming deadly.

30 Jan 2020

US life expectancy increases for the first time in 4 years

New data collected by the Centers for Disease Control and Prevention report that life expectancy in the United States increased in 2018.

30 Jan 2020

ERA4TB to transform the development of new therapies for tuberculosis

With a team of more than thirty public and private organisations and a budget over 200 million euro, ERA4TB aims to radically transform the way in which new therapies are developed for the treatment of tuberculosis.

30 Jan 2020

Study may help develop ibrutinib-based combination therapies for blood cancer

Chronic lymphocytic leukemia (CLL) is the most common form of blood cancer (leukemia) in the Western world, affecting approximately 1.2% of all cancer patients.

30 Jan 2020

Even extinguished cigarettes release toxins, shows study

Cigarette butts pile up in parks, beaches, streets and bus stops, places where all types of littering are frowned upon.

30 Jan 2020

Global funding for neglected disease research reaches a record high

For the first time, global funding for neglected disease R&D grew for three consecutive years, reaching a record high of more than US$4.05 billion in 2018.

30 Jan 2020

Discrimination may cause black and Hispanic patients to wait longer for primary care appointment

Discrimination may cause black and Hispanic patients to wait longer for a scheduled primary care appointment, according to a new Tulane University study published in JAMA Network Open.

30 Jan 2020

Novel inhibitor to fight metastatic prostate cancer shows promise

When prostate cancer spreads it is often a deadly disease, but now a Stony Brook University-led research team believes a new approach that inhibits a specific fatty acid binding protein (FABP) may be the key to halting disease progression.

30 Jan 2020

New treatment target could change the outlook of patients at risk of kidney injury

Kidney injury is a dreaded complication of commonly performed procedures such as coronary angiography or cardiac surgery, often stopping physicians and patients in their tracks.

30 Jan 2020

New web resource proves to be feasible for use among suicidal adults

Access to firearms and other lethal methods of suicide during periods of risk can make it more likely that a suicide attempt will end in death.

29 Jan 2020

Researchers examine abnormal neuron activity in Rett syndrome

The brain undergoes dramatic change during the first years of life. Its circuits readily rewire as an infant and then child encounters new sights and sounds, taking in the world and learning to understand it. As the child matures and key developmental periods pass, the brain becomes less malleable--but certain experiences create opportunities for parts of the adult brain to rewire and learn again.

29 Jan 2020

Study: 25% of pathogenic bacteria can spread antibiotic resistance directly to peers

Biomedical engineers at Duke University have demonstrated that at least 25 percent of antibiotic-resistant pathogenic bacteria found in clinical settings are capable of spreading their resistance directly to other bacteria.

29 Jan 2020

New method for delivering NSCs to spinal cord injuries may boost repair efforts

Writing in the journal Stem Cells Translational Medicine, an international research team, led by physician-scientists at University of California San Diego School of Medicine, describe a new method for delivering neural precursor cells (NSCs) to spinal cord injuries in rats, reducing the risk of further injury and boosting the propagation of potentially reparative cells.

29 Jan 2020

New review calls for recognition of 'take-home' exposures as a public health hazard

Workers in many industries inadvertently bring home toxic contaminants, endangering the health of their families. Those at greatest risk are the least likely to benefit from current regulations.

29 Jan 2020

Researchers identify potential target in the fight against MERS

First identified in 2012, the MERS-coronavirus is capable of causing severe and often fatal pneumonia. There are no effective treatments for MERS.

29 Jan 2020

Research reveals key molecular target for colorectal cancer therapy

Serine racemase is a multifunctional enzyme that carries out several different reactions in human cells, including the conversion of L-serine into pyruvate.

29 Jan 2020

Study opens up strategies for early diagnosis, treatment of diseases linked to chronic inflammation

Claudio Franceschi, a world-renowned scientist, professor at the University of Bologna (Italy) and head of the Research Laboratory for Systems Medicine of Healthy Aging at Lobachevsky University, together with other members of an international research team, has described the mechanisms underlying chronic inflammation and identified several risk factors leading to disease.

29 Jan 2020

Study reveals how the gut's protective mechanisms ramp up with food intake

A new study has revealed how the gut's protective mechanisms ramp up significantly with food intake, and at times of the day when mealtimes are anticipated based on regular eating habits.

29 Jan 2020