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Nab-Paclitaxel drug combo reduces risk of breast cancer recurrence

A recent large German study has shown that a new combination therapy for breast cancer treatment leads to a lowered risk of the disease coming back. A commentary on this landmark clinical trial has been published in the latest issue of the Journal of Clinical Oncology by the researchers Masey Ross and Charles Geyer Jr. from the VCU Massey Cancer Center. The commentary was titled, “Nab-Paclitaxel: A New Standard of Care in Neoadjuvant Therapy of High-Risk Early Breast Cancer?”

27 Aug 2019

Australian overdose deaths - sinister new trend

The incidence of unintentional overdose leading to death is still going up in Australia, says Australia’s Annual Overdose Report 2019. Most of the drugs involved are very powerful. They include prescription opioids and benzodiazepines as well as illegal substances like heroin and crystal methamphetamine or “ice”.

27 Aug 2019

Excess body fat linked to greater risk of developing depression

Carrying ten kilograms of excess body fat increases the risk of depression by seventeen per cent. The more fat, the greater the probability of developing depression. This is the main conclusion of a new study carried out by researchers from Aarhus University and Aarhus University Hospital, Denmark.

27 Aug 2019

Technostress linked to addiction for social media platforms

Social network users risk becoming more and more addicted to social media platforms even as they experience stress from their use.

27 Aug 2019

Gold nanoparticles shown to safely, effectively ablate low- to intermediate-grade prostate tumors

Biocompatible gold nanoparticles designed to convert near-infrared light to heat have been shown to safely and effectively ablate low- to intermediate-grade tumors within the prostate, according to a study conducted at the Icahn School of Medicine and published in the journal Proceedings of the National Academy of Sciences.

27 Aug 2019

Teens with higher prenatal organophosphate exposure show altered brain activity

Organophosphates are among the most commonly used classes of pesticides in the United States, despite mounting evidence linking prenatal exposure to the chemicals to poorer cognition and behavior problems in children.

27 Aug 2019

Infants with genetic epilepsy show better response to treatment with ketogenic diet

Infants and young children with epilepsy due to a confirmed genetic abnormality had a better response to treatment with ketogenic diet compared to patients with other types of epilepsy, according to a review of 10-year experience at Ann & Robert H. Lurie Children's Hospital of Chicago. Results were published in Scientific Reports.

27 Aug 2019

Traumatic brain injuries could be healed using peptide hydrogels

Traumatic brain injury (TBI) –– defined as a bump, blow or jolt to the head that disrupts normal brain function –– sent 2.5 million people in the U.S. to the emergency room in 2014, according to statistics from the U.S. Centers for Disease Control and Prevention.

27 Aug 2019

Many drug manufacturers fail to complete the FDA approval process, research reveals

The Food and Drug Administration's Accelerated Approval Program was created in 1992 to significantly accelerate the ability to bring certain new drugs to market.

27 Aug 2019

Front-line primary care providers given tools to play larger role in tackling opioid abuse

Buprenorphine and naltrexone can help break a person's addiction to life-threatening opioid use disorder, but they can be hard for front-line, primary care providers to prescribe, according to researchers at McGovern Medical School at The University of Texas Health Science Center.

27 Aug 2019

Study explores cannabis use in young adult cancer patients

Cannabis can help alleviate some of the symptoms of cancer and its treatment, and a new study examines the prevalence of its use among young adult cancer patients now that medical cannabis is becoming increasingly available.

27 Aug 2019

Researchers develop simple method for isolating placental cells from cervical swabs

Brown University researchers have developed a simple method for isolating placental cells from cervical swabs. The technique, described in the journal Scientific Reports, could aid in developing less invasive ways of diagnosing genetic disorders in developing fetuses.

27 Aug 2019

Sick mitochondria pollute the cells, cause telomere damage

Researchers at UPMC Hillman Cancer Center provide the first concrete evidence for the long-held belief that sick mitochondria pollute the cells they're supposed to be supplying with power.

27 Aug 2019

Multiple-birth infants have higher risk of wrong-patient order errors in NICU

Multiple-birth infants had a significantly higher risk of wrong-patient order errors compared with singletons in neonatal intensive care units, according to a new study by researchers at Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian Hospital.

27 Aug 2019

Genetically altering protein in colon cancer cells may enhance efficacy of chemotherapy

Colorectal cancer outcomes may improve by genetically altering an immune-regulatory protein in cancer cells, making the cells more vulnerable to chemotherapy. That's according to new Mayo Clinic research.

27 Aug 2019

Multi-site study of noninvasive brain stimulation to improve upper limb function after spinal cord injury

Kessler Foundation is one of three sites participating in a study of noninvasive brain stimulation to improve upper limb function funded by the U.S. Department of Defense Congressionally Directed Medical Research Programs titled, "Improving Spinal Cord Injury Rehabilitation Interventions by Retraining the Brain." Ela Plow, PhD, is principal investigator for the Cleveland Clinic; Svetlana Pundik, PhD, is principal investigator for the Louis B. Stokes VA Cleveland Medical Center; and Gail Forrest, PhD, is principal investigator for the Foundation, which received a sub-award of $778,000. Dr. Forrest is director of the new Center for Spinal Stimulation at Kessler Foundation.

27 Aug 2019

Human infective nematode identified in canine carriers for the first time

A human infective nematode found in remote northern areas of Australia has been identified in canine carriers for the first time.

27 Aug 2019

Studying human behavior might help curb mosquito-borne illness

Control and prevention of Aedes-transmitted viruses, such as dengue, chikungunya, or Zika relies heavily on vector control approaches. Given the effort and cost involved in implementation of vector control, targeting of control measures is highly desirable. However, it is unclear to what extent the effectiveness of highly focal and reactive control measures depends on the commuting and movement patterns of humans.

27 Aug 2019

Sea snail compound shows potential as new anti-cancer pharmaceutical

The remarkable ability of a small Australian sea snail to produce a colorful purple compound to protect its eggs is proving even more remarkable for its potential in a new anti-cancer pharmaceutical.

27 Aug 2019

Researchers gain new insights into types of germ cell tumors

Germ cell tumors constitute a diverse group of rare tumors, which occur in the testes, ovaries and also in other places. Some germ cell tumors exist prenatally, while others present during or after puberty. The majority is benign.

27 Aug 2019