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Protein SV2A levels could explain poor neuronal connections in schizophrenia

A team of researchers have found that persons with schizophrenia may have lower levels of certain specific proteins that show up on their brain scans. This could help as diagnostic tools, say experts. The new study titled, “Synaptic density marker SV2A is reduced in schizophrenia patients and unaffected by antipsychotics in rats”, is published in the latest issue of the journal Nature Communications.

14 Jan 2020

UT Southwestern researchers explain racial disparities in heart failure risk

Researchers at UT Southwestern have uncovered evidence that the higher prevalence of "malignant" enlargement of the heart among blacks contributes to the higher incidence of heart failure in this population.

14 Jan 2020

Overactivation of neuroimmune gene leads to schizophrenia-like changes in mice

Excessive activity of an immune system gene previously linked to schizophrenia reproduces neural and behavioral aspects of the disease in mice, according to a new study publishing on January 14 in the open-access journal PLOS Biology by Ashley Comer and Alberto Cruz-Martín of Boston University and colleagues.

14 Jan 2020

KU Leuven researchers develop new antibacterial strategy that weakens bacteria

Bioscience engineers from KU Leuven in Belgium have developed a new antibacterial strategy that weakens bacteria by preventing them from cooperating. Unlike with antibiotics, there is no resistance to this strategy, because the non-resistant bacteria outnumber resistant ones.

14 Jan 2020

Flame retardants and pesticides responsible for intellectual disabilities among millions

A few decades back one of the commonest environmental causes of intellectual disabilities among babies was exposure to lead and mercury. A new study reveals that while exposure to these heavy metals is on the decline, there is risk of other toxic chemicals. Researchers have found that chemicals present in pesticides and flame retardants could be causing over a million cases of intellectual disabilities among babies between 2001 and 2016.

14 Jan 2020

Study reveals how clotting protein and blood platelets promote immune evasion, tumor progression

A new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute reveals how a clotting protein and blood platelets can promote cancer progression and suppress immune responses to cancer.

14 Jan 2020

Biomaterial-based vaccine has potential to completely eliminate AML cells

Acute myeloid leukemia (AML) is a deadly blood cancer that originates in the bone marrow and kills most of its victims within five years. Chemotherapy has been the standard AML treatment for over 40 years, and while it often causes the cancer to go into remission, it rarely completely eliminates the cancerous cells, which then lead to disease recurrence in nearly half of treated patients.

14 Jan 2020

Study shows how treatment resistance develops in patients with bile duct cancer

A new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute shows how resistance to a promising targeted drug develops in patients with a rare, lethal cancer of the bile ducts called cholangiocarcinoma.

14 Jan 2020

Cannabinoids can alleviate some symptoms of endometriosis

Initial results from treating endometriosis in mice with cannabinoids suggest they can alleviate some symptoms of the disease, according to a new study in the open-access journal eLife.

14 Jan 2020

UMN and Windgap Medical collaborate to design cyanide antidote autoinjector

The University of Minnesota Twin Cities and Windgap Medical have received a $3.2 million grant from the National Institutes of Health to develop a new device to quickly administer a recently developed antidote for cyanide poisoning.

14 Jan 2020

Scientists discover powerful molecule that explains why people with anxiety use marijuana

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14 Jan 2020

Rapid diagnosis centers cut waiting times for patients with non-specific symptoms

A rapid diagnosis centre has cut waiting times for patients with non-specific symptoms who may have cancer from 84 days to 6, and costs less than current usual care if used at more than 80% of capacity, a new study by Swansea University researchers and NHS colleagues has shown.

14 Jan 2020

AI replaces prick test to detect blood sugar levels

Tracking fluctuations in blood glucose levels is crucial for monitoring diabetic patients. Strict glucose monitoring reduces the risk of hypoglycemia, which can be potentially fatal if it’s not treated promptly.

14 Jan 2020

Scientists unveil molecular changes that show why some people age faster than others

It’s still a mystery why some people age faster than others, and some may look younger than their peers. Aging is inevitable but the molecular changes linked to it are not well understood.

14 Jan 2020

MGH laboratory develops new technology to reduce fat

How cool is this: the Massachusetts General Hospital laboratory that invented cryolipolisis or "Coolsculpting," a popular non-surgical method for reducing fat under the skin, is developing a new form of the technology that can selectively reduce fat almost anywhere in the body using a safe, injectable ice solution or "slurry."

14 Jan 2020

Reducing albuterol use in children with bronchiolitis without compromising care

Bronchiolitis, a lung infection that is one of the most common reasons for hospitalizations in young children, is most prevalent during the winter months and is usually treated with albuterol delivered via inhalers, despite evidence showing no benefit in most patients.

14 Jan 2020

Sugar intake influences brain reward circuitry

The idea of food addiction is a very controversial topic among scientists. Researchers from Aarhus University have delved into this topic and examined what happens in the brains of pigs when they drink sugar water. The conclusion is clear: sugar influences brain reward circuitry in ways similar to those observed when addictive drugs are consumed.

14 Jan 2020

Eating more vegetables provides no extra protection for men with prostate cancer

National guidelines recommend that men with prostate cancer eat a vegetable-rich diet, suggesting it might decrease cancer progression and death.

14 Jan 2020

Tailored mesoporous silica particles could be used to treat obesity, diabetes

Engineered ingestible molecular traps created from mesoporous silica particles (MSPs) introduced to the gut can have an effect on food efficiency and metabolic risk factors. The results from studies on mice, published in Nanomedicine, demonstrate the potential to reduce the energy uptake into the body and could lead to new treatments for obesity and diabetes.

14 Jan 2020

Exosome treatment promotes remarkable stroke recovery in swine models

It's been almost a quarter century since the first drug was approved for stroke. But what's even more striking is that only a single drug remains approved today.

14 Jan 2020