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Using gene therapy strategies to rejuvenate aging cells and treat osteoarthritis

Aging is a risk factor for the development of osteoarthritis (OA), a chronic disease characterized by degeneration of articular cartilage leading to pain and physical disability.

28 Mar 2019

Just one dose of glucose while on keto diet can damage blood vessels

The often embraced 'cheat day' is a common theme in many diets and the popular ketogenic diet is no exception. But new research from UBC's Okanagan campus says that just one 75-gram dose of glucose--the equivalent a large bottle of soda or a plate of fries--while on a high fat, low carbohydrate diet can lead to damaged blood vessels.

28 Mar 2019

Researchers develop new technology to mass produce cerebral cortex neurons

Korea Brain Research Institute (KBRI, President Pann Ghill Suh) announced on Mar. 4 that its research team led by principal researcher Yoichi Kosodo developed a technology to mass produce cerebral cortex neurons utilizing Induced pluripotent Stem Cells.

28 Mar 2019

Garvan researchers develop more accurate method to diagnose cancer subtypes

Developed by researchers at the Garvan Institute of Medical Research, this potential diagnostic method screens a cancer sample for 'fusion genes', estimated to be linked to one in five cancers, and may provide a more accurate snapshot of rearranged DNA found in cancer.

28 Mar 2019

Study describes new muscular disease caused by mutation in myoglobin gene

Researchers of the Bellvitge Biomedical Research Institute led by Dr. Montse Olivé have described in Nature Communications a new muscular disease caused by a mutation in the myoglobin gene.

28 Mar 2019

Study: Lack of physician guidance and fear of side effects are reasons for refusing statins

Despite national guidelines indicating that statins can lower risk of heart attack and stroke, many patients who could benefit do not take them.

28 Mar 2019

Study sheds light on why some people hear 'hear' silent flashes or movement

A synaesthesia-like effect in which people 'hear' silent flashes or movement, such as in popular 'noisy GIFs' and memes, could be due to a reduction of inhibition of signals that travel between visual and auditory areas of the brain, according to a new study led by researchers at City, University of London.

28 Mar 2019

Vitamin C can reduce the length of ICU stay

Vitamin C administration shortened the length of stay in the intensive care unit on average by 8% in 12 trials with 1766 patients according to a meta-analysis published in Nutrients.

28 Mar 2019

Exercise helps prevent cartilage degradation caused by osteoarthritis, study shows

Exercise helps to prevent the degradation of cartilage caused by osteoarthritis, according to a new study from Queen Mary University of London.

27 Mar 2019

Low intake of red and processed meats may increase risk of mortality

A new study out of Loma Linda University Health suggests that eating red and processed meats -- even in small amounts -- may increase the risk of death from all causes, especially cardiovascular disease.

27 Mar 2019

Common drug may lead to obesity in offspring

Metformin,a common drug used to treat type 2 diabetes, is often used during pregnancy where the mother suffersfrom polycystic ovary syndrome.

27 Mar 2019

Researchers discover underlying cause of hereditary muscle disease

Researchers at Karolinska Institutet have discovered the underlying cause of a hereditary muscle disease first characterised in a Swedish family in 1980. It proves to be the first identified disease caused by defective myoglobin, the protein that transports oxygen in muscle cells.

27 Mar 2019

Supermarket offers linked to rise in obesity rates

A new report by CRUK reveals that shoppers who look for special offers in the supermarket are more likely to be obese or overweight.

27 Mar 2019

People born with short telomeres found to have short-lived immune system cells

Scientists at Johns Hopkins say they have found that people born with abnormally short chromosome endcaps, or telomeres, have immune system cells that age and die prematurely.

27 Mar 2019

Using connectomics to gain insight into epilepsy

Abnormalities in structural brain networks and how brain regions communicate may underlie a variety of disorders, including epilepsy, which is one focus of a two-part Special Issue on the Brain Connectome in Brain Connectivity, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

27 Mar 2019

Treatment at low-scoring hospitals may increase risk for repeat heart attack and death

Heart attack patients treated at hospitals with low care scores are at greater risk for another heart attack and/or death due to cardiovascular causes, Rutgers researchers found.

27 Mar 2019

Tumor-associated macrophages block activity of chemotherapy drug in pancreatic cancer

A frontline chemotherapy drug given to patients with pancreatic cancer is made less effective because similar compounds released by tumor-associated immune cells block the drug's action, research led by the University of Michigan Rogel Cancer Center found.

27 Mar 2019

Study offers new insights for vaccine development to prevent RSV disease

In healthy adults, RSV, or respiratory syncytial virus, feels like the common cold with a runny nose, chest congestion and cough.

27 Mar 2019

Simple parameter can help surgeons in making decisions to treat aneurysms

Aneurysms form as abnormal bulges or balloonings over an artery, and, if ruptured, can lead to serious health complications or even death. Some aneurysms can exist for a long time without rupturing, and the surgery involved in treating aneurysms can be quite risky, so a parameter to help guide surgeons is needed.

27 Mar 2019

Researchers study how the auditory system achieves accurate speech recognition

For humans to achieve accurate speech recognition and communicate with one another, the auditory system must recognize distinct categories of sounds - such as words - from a continuous incoming stream of sounds.

27 Mar 2019