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Long-term use of inexpensive weight-loss drug may be safe and effective

An inexpensive weight-loss drug approved 60 years ago for only short-term use also may be safe and effective for longer-term treatment, according to a study conducted by researchers at Wake Forest Baptist Health and the Patient Outcomes Research to Advance Learning network.

22 Mar 2019

Surprising discovery offers clues to limit graft-vs.-host disease

A protein that protects people with inflammatory bowel disease has quite a different effect in graft-vs.-host disease, a common and challenging side effect of bone marrow transplants.

22 Mar 2019

Study provides new pathway for controlling inflammation

UT Southwestern researchers have identified two proteins that act as gatekeepers to dampen a potentially life-threatening immune response to chronic infection.

22 Mar 2019

Exploring pathophysiological factors that link sleep problems and Alzheimer's disease

A new article explores the pathophysiological factors that link sleep disturbances and Alzheimer's disease.

22 Mar 2019

Using the Mastermind strategy in brain research

The brain is a complex organ, and researching medicine to treat brain disorders is equally if not more complex. Elizabeth (Liesbeth) de Lange, Professor of Predictive Pharmacology, calls for a structured approach.

22 Mar 2019

Study provides new insight into blood cell and immune cell production

A healthy adult makes about 2 million blood cells every second, and 99 percent of them are oxygen-carrying red blood cells. The other one percent are platelets and the various white blood cells of the immune system.

22 Mar 2019

New survey indicates need of attention to neglected tropical diseases

Although neglected diseases account for 11% of the global disease burden, they are targeted by only a small proportion of the new drugs developed every year.

22 Mar 2019

Bacteria and innate immune factors in birth canal, cervix may be key to predicting preterm births

Spontaneous preterm birth, defined as birth before 37 weeks of gestation, and the related complications, are the largest contributors to infant death in the United States and worldwide, according to the World Health Organization.

22 Mar 2019

Hidden differences between pathology of CTE and Alzheimer's disease discovered

An international team of scientists at Indiana University School of Medicine, University of Kansas and the U.K. Medical Research Council have dismantled the belief that Alzheimer's disease and Chronic Traumatic Encephalopathy have identical pathology.

22 Mar 2019

Repurposing drugs to outsmart cancers

In an article published today by SAGE Publishing, investigators from The Nagourney Cancer Institute and The Albert Einstein Israelite Hospital in São Paulo, Brazil, announced a new approach to identifying effective treatments for patients with advanced metastatic cancers. A drug commonly used to treat kidney and liver cancer was discovered effective for breast cancer, which may open new drug therapies to patients regardless of tumor type.

22 Mar 2019

Naltrexone implant more effective in reducing relapses in HIV patients with opioid addiction

When patients with HIV who are also battling opioid dependence go without addiction treatment, they are more likely to stop taking their HIV medications than drug-free patients.

22 Mar 2019

The Brain Institute wins $7.04 million grant to investigate 'neurophilosphy of free will'

The newly-minted Institute for Interdisciplinary Brain and Behavioral Science (The Brain Institute) at Chapman University, with Dr. Uri Maoz as project leader, is the recipient of a total of $7.04 million to study how the human brain enables conscious control of decisions and actions.

22 Mar 2019

Research links participation in team sports to larger hippocampal volumes in children

Adult depression has long been associated with shrinkage of the hippocampus, a brain region that plays an important role in memory and response to stress. Now, new research from Washington University in St. Louis has linked participation in team sports to larger hippocampal volumes in children and less depression in boys ages 9 to 11.

22 Mar 2019

New nanotechnology approach shows promise in treating triple negative breast cancer

Unlike the three most common forms of breast cancer, triple negative breast cancer has no currently approved targeted therapies for treatment. That was one of the reasons it was chosen as a disease area of focus for the Indiana University Precision Health Grand Challenge initiative, aimed to research and develop better treatments, cures or preventions, as quickly as possible.

22 Mar 2019

Pitt engineers win $550,000 NSF CAREER award to develop new intervention for people with ASD

Autism was first described by U.S. researchers more than 70 years ago, and today the Centers for Disease Control and Prevention estimates that 1 in 59 children are identified with autism spectrum disorder, affecting more than 3.5 million Americans.

22 Mar 2019

Creating diverse pool of trained scientists to address Alzheimer's research needs

Roberta Diaz Brinton, PhD, an internationally recognized expert on Alzheimer's disease and inaugural director of the Center for Innovation in Brain Science at the University of Arizona Health Sciences, has received a five-year, $1.8 million grant from the National Institutes of Health Institute on Aging.

22 Mar 2019

Lian wins ENGINE grant for stem-cell-based therapy to treat Type 1 diabetes

Xiaojun "Lance" Lian, assistant professor of biomedical engineering, was one of three recipients of the College of Engineering's ENGineering for Innovation & Entrepreneurship grant for "Small Molecule-Based Definitive Endoderm Kit and Pancreatic Progenitor Kit for Stem Cell Research and Therapy."

22 Mar 2019

City of Hope exhibits current studies and data on cancer therapies at AACR

City of Hope, a world-renowned independent research and treatment center for cancer and diabetes, will showcase ongoing studies and data on chimeric antigen receptor T cell therapy, immunotherapy against solid tumors and more at the American Association for Cancer Research annual meeting from March 29 through April 3 in Atlanta.

22 Mar 2019

Brain process common to sleep and aging discovered

Oxford University researchers have discovered a brain process common to sleep and ageing in research that could pave the way for new treatments for insomnia.

22 Mar 2019

Gift cards linked to better outcomes in employee wellness programs

Employee wellness programs are popular among businesses seeking to increase productivity and cut health care costs. However, many firms have struggled to reap those benefits due to low employee motivation.

22 Mar 2019

Medical Research News

Long-term use of inexpensive weight-loss drug may be safe and effective

Surprising discovery offers clues to limit graft-vs.-host disease

Study provides new pathway for controlling inflammation

Exploring pathophysiological factors that link sleep problems and Alzheimer's disease

Using the Mastermind strategy in brain research

Study provides new insight into blood cell and immune cell production

New survey indicates need of attention to neglected tropical diseases

Bacteria and innate immune factors in birth canal, cervix may be key to predicting preterm births

Hidden differences between pathology of CTE and Alzheimer's disease discovered

Repurposing drugs to outsmart cancers

Naltrexone implant more effective in reducing relapses in HIV patients with opioid addiction

The Brain Institute wins $7.04 million grant to investigate 'neurophilosphy of free will'

Research links participation in team sports to larger hippocampal volumes in children

New nanotechnology approach shows promise in treating triple negative breast cancer

Pitt engineers win $550,000 NSF CAREER award to develop new intervention for people with ASD

Creating diverse pool of trained scientists to address Alzheimer's research needs

Lian wins ENGINE grant for stem-cell-based therapy to treat Type 1 diabetes

City of Hope exhibits current studies and data on cancer therapies at AACR

Brain process common to sleep and aging discovered

Gift cards linked to better outcomes in employee wellness programs

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

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