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MUSC researchers link higher levels of AGEs to ER-positive breast cancer risk

Poor diet and lack of exercise are associated with cancer development, but the underlying biology is not well understood. Advanced glycation end products could offer a biological link to help us understand how certain lifestyle behaviors increase cancer risk or lessen the likelihood that an anti-cancer therapy will be effective.

28 Dec 2018

New study describes various gene therapy strategies for treating Parkinson's disease

Parkinson's disease is a neurodegenerative disorder characterized by motor and nonmotor deficits majorly caused by the loss of dopaminergic cells in the Substantia Nigra pars compacta as well as the destruction of nigrostriatal pathway.

28 Dec 2018

Kidney disease risk gene found in more populations than previously known

In the largest population genomics investigation to date, a team of researchers at the Icahn School of Medicine at Mount Sinai, Stanford University, and the University of Colorado have discovered that kidney disease risk variants of the gene APOL1, previously known to affect African and African American populations, are also found at appreciable frequencies in Caribbean and Latin American populations.

28 Dec 2018

Speedier examinations may be useful in public health assessments of scabies

For years, the diagnosis of scabies has relied on time-consuming and intrusive full-body examinations. Now, researchers reporting in PLOS Neglected Tropical Diseases have found that an exam of just a patient's hands, feet and lower legs may have the potential to catch more than 90 percent of all scabies cases, regardless of severity.

28 Dec 2018

Scientists move one step closer towards treatment for low-grade gliomas with SYNODOS

Treatment for low-grade gliomas in patients living with neurofibromatosis type 1 are now one step closer thanks to recent research discoveries initiated and funded by the Children's Tumor Foundation.

28 Dec 2018

Sleeping sickness parasite exhibits metabolic flexibility and adaptability

Parasitic protozoa called trypanosomes synthesize sugars using an unexpected metabolic pathway called gluconeogenesis, according to a study published December 27 in the open-access journal PLOS Pathogens by David Horn of the University of Dundee in the UK, and colleagues.

28 Dec 2018

Exposure to second-hand tobacco smoke triggers changes in the heart's electrical activity

Continuous indoor exposure to second-hand tobacco smoke triggers changes in the heart's electrical activity, known as cardiac alternans, that can predict cardiac arrhythmia and sudden cardiac death, a new study from UC Davis Health researchers shows.

28 Dec 2018

Reducing alcohol use could help quit daily smoking habit

If quitting smoking is one of your New Year's resolutions, you might want to consider cutting back on your drinking, too.

28 Dec 2018

Physical contact with primates puts people at risk of infection with new diseases

Animal diseases that infect humans are a major threat to human health, and diseases often spillover to humans from nonhuman primates. Now, researchers reporting in PLOS Neglected Tropical Diseases have carried out an extensive social sciences evaluation of how populations in Cameroon interact with nonhuman primates, pointing toward behaviors that could put people at risk of infection with new diseases.

28 Dec 2018

Proportion of cancer cases related to obesity varies considerably by state

A new study looking at the share of cancers related to obesity finds an at least 1.5-fold difference between states with the highest and lowest proportions.

28 Dec 2018

Researchers conduct psycho-educational study on early stage breast cancer patients

Cancer is a psychologically traumatic experience for affected individuals. Chemotherpautic medications can also be painful to the same patients.

28 Dec 2018

Researchers discover key mechanism in the brain that enables us to rapidly focus attention

University of Queensland researchers have discovered a key mechanism in the brain that may underlie our ability to rapidly focus attention.

28 Dec 2018

New research tests Co-enzyme Q10 as potential treatment for Chronic Kidney disease

Chronic Kidney disease is highly associated with all-cause mortality, Diabetic Nephropathy, cardiovascular events and hospitalization whether the patient has an existing risk or current cardiovascular disease or not.

28 Dec 2018

Late-life mortality plateaus can result from diverse statistical errors

Human error, not human biology, largely accounts for the apparent decline of mortality among the very old, according to a new report publishing on December 20 in the open-access journal PLOS Biology by Saul Newman of Australia National University in Canberra.

27 Dec 2018

Scientists gain new insight into aggressive breast cancers

Scientists from Cardiff University have uncovered a protein which drives aggressive breast cancer and could be targeted for developing new and improved therapies.

27 Dec 2018

Researchers develop vaccine effective against emerging tick-borne virus in mice

A group of researchers led by Michael Diamond of Washington University in St. Louis have developed a vaccine that is effective in mice against Powassan virus, an emerging tick-borne virus that can cause life-threatening encephalitis in humans.

27 Dec 2018

Targeting thymidylate biosynthesis in kinetoplastid and apicomplexan protozoans

Kinetoplastid and apicomplexan parasites include protozoans which are responsible for human diseases, and cause a serious impact on human health and the socioeconomic growth of developing countries. Chemotherapy is the main option to control these pathogenic organisms.

27 Dec 2018

Study uncovers how skin ages, loses fat and immunity

Dermal fibroblasts are specialized cells deep in the skin that generate connective tissue and help the skin recover from injury. Some fibroblasts have the ability to convert into fat cells that reside under the dermis, giving the skin a plump, youthful look and producing a peptide that plays a critical role in fighting infections.

27 Dec 2018

Researchers discover extent of opioid use and abuse in head and neck cancer patients

Cancer patients are often prescribed pain medications, for example during recovery from surgical procedures. However, for many cancer patients, the use of opioid pain medications during treatment can be a gateway to misuse or addiction once treatment ends.

27 Dec 2018

Research findings expand understanding of how memory works

Two Veterans Affairs researchers have explored how memory is tied to the hippocampus, with findings that will expand scientists' understanding of how memory works.

27 Dec 2018

Medical Research News

MUSC researchers link higher levels of AGEs to ER-positive breast cancer risk

New study describes various gene therapy strategies for treating Parkinson's disease

Kidney disease risk gene found in more populations than previously known

Speedier examinations may be useful in public health assessments of scabies

Scientists move one step closer towards treatment for low-grade gliomas with SYNODOS

Sleeping sickness parasite exhibits metabolic flexibility and adaptability

Exposure to second-hand tobacco smoke triggers changes in the heart's electrical activity

Reducing alcohol use could help quit daily smoking habit

Physical contact with primates puts people at risk of infection with new diseases

Proportion of cancer cases related to obesity varies considerably by state

Researchers conduct psycho-educational study on early stage breast cancer patients

Researchers discover key mechanism in the brain that enables us to rapidly focus attention

New research tests Co-enzyme Q10 as potential treatment for Chronic Kidney disease

Late-life mortality plateaus can result from diverse statistical errors

Scientists gain new insight into aggressive breast cancers

Researchers develop vaccine effective against emerging tick-borne virus in mice

Targeting thymidylate biosynthesis in kinetoplastid and apicomplexan protozoans

Study uncovers how skin ages, loses fat and immunity

Researchers discover extent of opioid use and abuse in head and neck cancer patients

Research findings expand understanding of how memory works

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

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