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Gene-editing technology enhances T cell immunotherapies for treating cancer

Last year, the Food and Drug Administration approved the first cellular immunotherapies to treat cancer. These therapies involve collecting a patient's own immune cells -- called T cells -- and supercharging them to home in on and attack specific blood cancers, such as hard-to-treat acute lymphoblastic leukemia and non-Hodgkin lymphoma.

6 Mar 2018

People 85 and older with high cholesterol have reduced risk for cognitive decline, study reports

People aged 85 and older whose total cholesterol had increased from their levels at midlife had a reduced risk for marked cognitive decline, compared with those a decade younger whose cholesterol was similarly elevated, Mount Sinai researchers report in a new study.

6 Mar 2018

Study findings establish basis for epigenetic link between aging and Alzheimer's disease

Although certain genetic variants increase the risk of Alzheimer's disease (AD), age is the strongest known risk factor. But the way in which molecular processes of aging predispose people to AD, or become impaired in AD remains a mystery.

6 Mar 2018

Researchers aim to to better predict future chronic opioid therapy in hospital patients

Researchers at the University of Colorado Anschutz Medical Campus are working to develop statistical models to better predict which patients will be prescribed opioid medications long-term following discharge from a hospital stay.

6 Mar 2018

Distorted memories play role in preserving knowledge for dementia patients, researchers say

Some memories containing inaccurate information can be beneficial to dementia sufferers because it enables them to retain key information researchers say.

6 Mar 2018

Study suggests bright lights inhibit the production of melatonin in preschoolers

A new study has found that exposure to bright light before bed time inhibits the production of sleep-promoting hormone, melatonin, in preschoolers.

6 Mar 2018

Treatments targeted to enhance brain neurotrophic factor signaling may improve memory functions

Treatments targeted to enhance brain neurotrophic factor signaling could improve memory functions in Alzheimer's disease even though they don't alter brain amyloid burden, according to recent research from the University of Eastern Finland.

6 Mar 2018

Neurocognitive deficits worsen outcomes for joint replacement surgery, finds study

Patients with undiagnosed neurocognitive deficits are more likely to undergo joint replacement surgeries and suffer worse outcomes, finds study.

6 Mar 2018

Strict eating schedule can help clear away protein responsible for Huntington disease in mice

New research from the University of British Columbia suggests that following a strict eating schedule can help clear away the protein responsible for Huntington disease in mice.

6 Mar 2018

Levels of inflammatory biomarkers could predict effectiveness of ECT for people with depression

People with major depression that has not been well controlled by medications and who have a biomarker in their blood indicating a higher level of inflammation may benefit more than people with less inflammation from electroconvulsive therapy to ease symptoms of their depression, according to a new UCLA study.

6 Mar 2018

$Analytic software identifies mortality risk after surgery in older patients with orthopedic fractures$

Analytic software identifies mortality risk after surgery in older patients with orthopedic fractures

Analytic software developed by orthopedic trauma surgeons at NYU Langone Health accurately identifies which middle-aged and elderly patients face a greater mortality risk following surgery for an orthopedic fracture, according to a new study.

6 Mar 2018

Novel tool helps identify risk for implant dislocation after hip replacement

A novel risk assessment tool helps identify which patients undergoing total hip replacement may be at higher risk for an implant dislocation after surgery, according to a new study from researchers at NYU Langone Health and described in the Best Poster in the Adult Reconstruction Hip at the American Academy of Orthopaedic Surgeons 2018 Annual Meeting in New Orleans.

6 Mar 2018

Helmet use linked to lower likelihood of cervical spine injury during motorcycle crash

Despite claims that helmets do not protect the cervical spine during a motorcycle crash and may even increase the risk of injury, researchers from the University of Wisconsin Hospitals and Clinics in Madison found that, during an accident, helmet use lowers the likelihood of cervical spine injury, particularly fractures of the cervical vertebrae.

6 Mar 2018

Johns Hopkins doctors successfully transplant hepatitis C-infected kidneys into virus-free patients

In a small study, doctors at Johns Hopkins have successfully transplanted 10 hepatitis C-infected kidneys into patients without hepatitis C and prevented the patients from becoming infected by hepatitis C. The success of these transplants could mean more organs being available for the nearly 100,000 people in the U.S. currently waiting for a kidney transplant.

6 Mar 2018

TSRI research offers explanation for why neurons die off in Parkinson's disease

An estimated 10 million people worldwide are living with Parkinson's disease--an incurable neurodegenerative disorder that leads to an increasing loss of motor control.

6 Mar 2018

Researchers develop gene therapy that treats a form of macular degeneration in canine model

Researchers from the University of Pennsylvania have developed a gene therapy that successfully treats a form of macular degeneration in a canine model.

6 Mar 2018

Parent mentors highly effective at providing Latino children with health insurance coverage

Latino children have the highest uninsured rate in the United States. However, new study findings in the March issue of Health Affairs show parent mentors are highly effective at providing uninsured Latino children with health insurance coverage.

6 Mar 2018

Research explores hormonal impact of nighttime light exposure on young children

Exposing preschoolers to an hour of bright light before bedtime almost completely shuts down their production of the sleep-promoting hormone melatonin and keeps it suppressed for at least 50 minutes after lights out, according to new University of Colorado Boulder research.

6 Mar 2018

UNC Lineberger study identifies genetic clues that explain how breast cancer metastasizes

Breast cancer is the second leading cause of cancer death in women in the United States, with most deaths caused by the cancer spreading beyond the breast.

6 Mar 2018

Restoring lipid synthesis could slow progression of pulmonary fibrosis

Pulmonary fibrosis, an ongoing process of scarring that leaves patients chronically short of breath, can progress in severity until the only course of treatment is lung transplant.

6 Mar 2018

Medical Research News

Gene-editing technology enhances T cell immunotherapies for treating cancer

People 85 and older with high cholesterol have reduced risk for cognitive decline, study reports

Study findings establish basis for epigenetic link between aging and Alzheimer's disease

Researchers aim to to better predict future chronic opioid therapy in hospital patients

Distorted memories play role in preserving knowledge for dementia patients, researchers say

Study suggests bright lights inhibit the production of melatonin in preschoolers

Treatments targeted to enhance brain neurotrophic factor signaling may improve memory functions

Neurocognitive deficits worsen outcomes for joint replacement surgery, finds study

Strict eating schedule can help clear away protein responsible for Huntington disease in mice

Levels of inflammatory biomarkers could predict effectiveness of ECT for people with depression

Analytic software identifies mortality risk after surgery in older patients with orthopedic fractures

Novel tool helps identify risk for implant dislocation after hip replacement

Helmet use linked to lower likelihood of cervical spine injury during motorcycle crash

Johns Hopkins doctors successfully transplant hepatitis C-infected kidneys into virus-free patients

TSRI research offers explanation for why neurons die off in Parkinson's disease

Researchers develop gene therapy that treats a form of macular degeneration in canine model

Parent mentors highly effective at providing Latino children with health insurance coverage

Research explores hormonal impact of nighttime light exposure on young children

UNC Lineberger study identifies genetic clues that explain how breast cancer metastasizes

Restoring lipid synthesis could slow progression of pulmonary fibrosis

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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