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Pitting pathogens against each other could prevent drug resistance emerging

Limiting the nutrient resources that pathogens depend on for replication could prevent the emergence of drug resistance, according to research findings. In a study published in Proceedings of the National Academy of Sciences, scientists have taken advantage of the competition that occurs between host pathogens to achieve successful treatment of infection with existing drugs, even when drug-resistant pathogens were present.

12 Dec 2017

Researchers explore neuro-psychological mechanisms behind existential threats

A group of Salzburg-based researchers led by the psychologist Eva Jonas investigates the neuro-psychological mechanisms behind existential threats. What exactly happens in the process between threat and defensive reaction is at the center of an ongoing study funded by the Austrian Science Fund FWF.

12 Dec 2017

Myriad Genetics announces new data on EndoPredict test at 2017 San Antonio Breast Cancer Symposium

Myriad Genetics, Inc., a leader in molecular diagnostics and personalized medicine, today announced new results from two studies with EndoPredict are being featured at the 2017 San Antonio Breast Cancer Symposium in San Antonio, Texas.

12 Dec 2017

Researchers identify promising solution for improving cystic fibrosis treatments

Researchers at the University of Montreal Hospital Research Centre have identified a promising solution to improving treatments offered to patients with cystic fibrosis.

12 Dec 2017

Novel compound inhibits mycomembrane biosynthesis and kills tuberculosis bacteria

Tuberculosis is one of the most widespread life-threatening infectious diseases. Not only does antibiotic resistance make treatment increasingly difficult, but the bacteria’s relatively impermeable mycomembrane also limits the effectiveness of many drugs.

12 Dec 2017

New report reveals steep rise in lung disease admissions to emergency departments during winter

An 80% rise in lung disease admissions to emergency departments in winter plays a major part in pushing our A&E services over the edge. Yet, only 10% of hospital trusts who responded to an FOI request had plans in place to make more beds available for respiratory patients warns a new report from the British Lung Foundation.

12 Dec 2017

Newly discovered molecular chaperones may soon be part of therapies for Huntington's disease

Huntington's disease is a neurodegenerative disease. It is always fatal. The disease is caused by a defect in the Huntingtin gene. To this day, no therapy will put a stop to the insidious disintegration of brain cells.

12 Dec 2017

Parkinson's progression delayed through high-intensity exercise, study says

A new phase 2, multi-site trial conducted at the Northwestern Medicine and University of Colorado School of Medicine suggests that for people with early-stage Parkinson's disease, high-intensity exercise three times a week is safe and can delay the worsening of motor symptoms.

12 Dec 2017

Urinary incontinence may affect learning and academic performance of teenagers

Continence problems are among the most common pediatric health problems. It's commonly believed that continence problems resolve with age in all children.

12 Dec 2017

High-intensity exercise decreases worsening of motor symptoms in Parkinson's patients

High-intensity exercise three times a week is safe for individuals with early-stage Parkinson's disease and decreases worsening of motor symptoms, according to a new phase 2, multi-site trial led by University of Colorado Anschutz Medical Campus and Northwestern Medicine scientists.

12 Dec 2017

Study finds rural-urban disparities in prevalence of dementia and cognitive impairment among seniors

Americans who live in urban areas tend to be healthier than individuals living in rural settings. While this healthcare disparity has been examined for more than a decade, researchers present the first nationally representative study to find that dementia and cognitive impairment have consistently been more prevalent among rural-dwelling seniors than urban dwelling seniors.

12 Dec 2017

Researchers find new role for SHARPIN protein in melanoma growth

Researchers at Sanford Burnham Prebys Medical Discovery and the Technion in Israel have found a new role for the SHARPIN protein. In addition to being one of three proteins in the linear ubiquitin chain assembly complex, regulating NFκB and other inflammatory molecules, SHARPIN modulates PRMT5, an epigenetic master switch that controls several proteins linked to melanoma. The research was published in The Journal of Clinical Investigation.

12 Dec 2017

Huntington's disease drug clears initial hurdles - raising hopes

Huntington’s disease is a genetic disorder that affects the brain progressively and has no known cure till date. In a breakthrough, the first drug that can target and reduce the cause behind this dreaded disease has been found to be effective, safe and well tolerated in a human clinical trial that was conducted by UCL scientists.

11 Dec 2017

Having older brothers may increase the likelihood of being gay

Scientists have found a distinct pattern that having older brothers raise the chances of the younger sibling being gay. This effect has been termed the “fraternal birth order effect”. They explain the biological reason behind this propensity in their new study that was published this week in the journal PNAS.

11 Dec 2017

Patient satisfaction, good caregiver communication linked to reduced risk of hospital readmission

A survey of patients admitted to Massachusetts General Hospital (MGH) has found that patients reporting greater levels of satisfaction with their care and good communication with the health care providers were significantly less like to readmitted to the hospital in the 30 days after discharge.

11 Dec 2017

NIH expected to award up to $70 million to launch Alzheimer's Clinical Trials Consortium

The National Institutes of Health is expected to award up to $70 million over five years to three physician-scientists to launch the Alzheimer's Clinical Trials Consortium, which will create a network of 35 Alzheimer's disease trial sites across the country with the goal of finding new ways to treat or prevent Alzheimer's.

11 Dec 2017

Anesthetics cause similar reaction in plants as they do in animals and humans

A new study published in Annals of Botany shows that plants react to anesthetics similarly to the way animals and humans do, suggesting plants are ideal objects for testing anesthetics actions in future.

11 Dec 2017

Study investigates link between cortisol levels of ICU patients’ family members and anxiety

When a loved one has been hospitalized in intensive care for a critical illness, many family members experience anxiety, depression, post-traumatic stress or other negative effects lasting months, according to new research led by Intermountain Medical Center in Salt Lake City.

11 Dec 2017

Researchers uncover novel strategy to program immune system for fighting cancer

Looking to bolster the body's immune system in the fight against infection and cancer, researchers at the University of California San Diego and their colleagues have identified a promising new strategy to program the immune system to meet the pathogen or malignancy in the tissues where they first pose a threat.

11 Dec 2017

Study provides new insights into mechanism of tumor survival in glioblastoma

A Northwestern Medicine study, published in the journal Cancer Cell, has provided new insights into a mechanism of tumor survival in glioblastoma and demonstrated that inhibiting the process could enhance the effects of radiation therapy.

11 Dec 2017

Medical Research News

Pitting pathogens against each other could prevent drug resistance emerging

Researchers explore neuro-psychological mechanisms behind existential threats

Myriad Genetics announces new data on EndoPredict test at 2017 San Antonio Breast Cancer Symposium

Researchers identify promising solution for improving cystic fibrosis treatments

Novel compound inhibits mycomembrane biosynthesis and kills tuberculosis bacteria

New report reveals steep rise in lung disease admissions to emergency departments during winter

Newly discovered molecular chaperones may soon be part of therapies for Huntington's disease

Parkinson's progression delayed through high-intensity exercise, study says

Urinary incontinence may affect learning and academic performance of teenagers

High-intensity exercise decreases worsening of motor symptoms in Parkinson's patients

Study finds rural-urban disparities in prevalence of dementia and cognitive impairment among seniors

Researchers find new role for SHARPIN protein in melanoma growth

Huntington's disease drug clears initial hurdles - raising hopes

Having older brothers may increase the likelihood of being gay

Patient satisfaction, good caregiver communication linked to reduced risk of hospital readmission

NIH expected to award up to $70 million to launch Alzheimer's Clinical Trials Consortium

Anesthetics cause similar reaction in plants as they do in animals and humans

Study investigates link between cortisol levels of ICU patients’ family members and anxiety

Researchers uncover novel strategy to program immune system for fighting cancer

Study provides new insights into mechanism of tumor survival in glioblastoma

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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