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Unique method opens door to development of simple diagnostic tests for myriad diseases

Researchers at the University of Pittsburgh have developed a unique method for detecting antibodies in the blood of patients in a proof-of-principle study that opens the door to development of simple diagnostic tests for diseases for which no microbial cause is known, including auto-immune diseases, cancers and other conditions.

10 Jun 2016

Smoking, obesity lower chances of achieving sustained remission in early RA patients

The results of a study presented today at the European League Against Rheumatism Annual Congress showed that the likelihood of achieving sustained remission in early rheumatoid arthritis (RA) is significantly lower in patients who smoke and who are obese.

10 Jun 2016

Study shows rheumatologists underestimate disease severity in OA patients

The results of a study presented today at the European League Against Rheumatism Annual Congress showed patients with osteoarthritis (OA) are more likely to have the impact of their condition underestimated by rheumatologists than patients with Rheumatoid Arthritis (RA).

10 Jun 2016

New RNA aptamer can prevent pathogenic protein misfolding

Several diseases occur when mutations cause misfolding of proteins. These include "serpinopathies" which is a group of rare heritable diseases. They are caused by mutations of so-called "serpin" inhibitors of proteolytic enzymes involved in blood coagulation, tissue remodeling, and other important physiological functions.

10 Jun 2016

New PsA-comorbidity index may help identify patients at risk of hospitalisation and premature death

The results of a study presented today at the European League Against Rheumatism Annual Congress showed that a newly developed method of evaluating the impact of different comorbidities in patients with Psoriatic Arthritis (PsA) can be used to prospectively identify those PsA patients at greater risk of hospitalisation and premature death.

10 Jun 2016

Women with SLE may have increased cervical cancer risk

The results of a study presented today at the European League Against Rheumatism Annual Congress found a doubled risk of pre-malignant cervical changes, and potentially also an increased risk of cervical cancer, among women with Systemic Lupus Erythematosus (SLE) compared to the general female population.

10 Jun 2016

Tackling Healthcare Challenges in a Changing World: an Interview with Professor Jeremy Nicholson

As individuals and as populations our risks of getting diseases are determined partly genetically and partly from the environment that we live in. An important part of that environment that mediates between the outside world and the inside world of our bodies is the microbiome.

10 Jun 2016

Implantable loop recorder can help diagnose heart rhythm abnormalities in SSc patients

The results of a study presented today at the European League Against Rheumatism Annual Congress showed that use of an easy to insert heart monitor in patients with systemic sclerosis (SSc) and no known heart disease enables early detection and treatment of potentially fatal cardiac arrhythmias.

10 Jun 2016

BNPs have potential to enable early diagnosis, long-term treatment of RA with minimal side effects

The results of a study presented today at the European League Against Rheumatism Annual Congress showed that tiny particles made of a biodegradable polymer (BNPs -- biodegradable polymer nanoparticles) have the potential to enable early detection and efficient long-term treatment of rheumatoid arthritis (RA), with minimal side effects.

10 Jun 2016

Type 1 diabetes occurs more frequently in patients with JIA

The results of a study involving more than 9,000 patients, presented today at the European League Against Rheumatism Annual Congress showed that Type 1 diabetes occurs significantly more frequently in patients with Juvenile Inflammatory Arthritis (JIA) than in the general population.

10 Jun 2016

Anti-CPP presence in bloodstream of RA patients correlates with drug response

The results of a study presented today at the European League Against Rheumatism Annual Congress showed that the presence of an antibody (anti-CPP ) in the bloodstream of patients with rheumatoid arthritis (RA) correlates with response to different drug treatments.

10 Jun 2016

Advanced imaging technique helps predict recovery in concussion patients

Using an advanced imaging technique, researchers at Albert Einstein College of Medicine and Montefiore Health System were able to predict which patients who'd recently suffered concussions were likely to fully recover.

10 Jun 2016

Antibody-positive patients treated with infliximab less likely to benefit from infliximab biosimilar

The results of a study presented today at the European League Against Rheumatism Annual Congress showed that when antibodies develop in response to the biological treatment Remicade (infliximab), they also cross-react with the biosimilar of infliximab (CT-P13: Inflectra or Remsima).

10 Jun 2016

Study finds non-disclosure of sexual orientation among behaviorally bisexual men

Research conducted at Columbia University's Mailman School of Public Health and Public Health Solutions examined the reasons why men who have had sex with both men and women choose not to disclose their sexual orientation -- particularly to their wives and girlfriends.

10 Jun 2016

Air pollution exposure may have direct role in triggering lupus among children and adolescents

The results of a study presented today at the European League Against Rheumatism Annual Congress show for the first time that an individual's exposure to air pollution may have a direct role in triggering disease activity as well as airway inflammation in children and adolescents with Systemic Lupus Erythematosus (SLE).

10 Jun 2016

Scientists discover new ZBTB7A gene mutation that promotes growth of cancer cells

Biomarkers play an important role in modern cancer medicine. They are used as tools to diagnose cancers more precisely and to better predict the course of the disease.

10 Jun 2016

Pre-procedure medication regimen could lower incidence of hospital readmission in lung caner patients

Researchers at the University of Cincinnati College of Medicine have found that putting liver cancer patients on a medication regimen prior to undergoing a certain treatment could lead to shorter hospital stays and less chance for readmission due to complications.

10 Jun 2016

Childhood exposure to chronic parental domestic violence linked to suicide attempts among adults

A new study by the University of Toronto, found the lifetime prevalence of suicide attempts among adults who had been exposed to chronic parental domestic violence during childhood was 17.3% compared to 2.3% among those without this childhood adversity.

10 Jun 2016

Minimal zinc deficiency can impede human and animal health

The trace element zinc has an impact on the essential metabolic functions of most living organisms. New research carried out by the Chair of Animal Nutrition at the Technical University of Munich has found that even minimal zinc deficiency impairs digestion, albeit without any typical symptoms such as skin problems or fatigue.

10 Jun 2016

Scientists map Zika and dengue-transmitting mosquitoes in U.S. counties

The mosquitoes known as Aedes aegypti and Aedes albopictus transmit arboviruses that are increasing threats to human health in the Americas, particularly dengue, chikungunya, and Zika viruses.

10 Jun 2016

Medical Research News

Unique method opens door to development of simple diagnostic tests for myriad diseases

Smoking, obesity lower chances of achieving sustained remission in early RA patients

Study shows rheumatologists underestimate disease severity in OA patients

New RNA aptamer can prevent pathogenic protein misfolding

New PsA-comorbidity index may help identify patients at risk of hospitalisation and premature death

Women with SLE may have increased cervical cancer risk

Tackling Healthcare Challenges in a Changing World: an Interview with Professor Jeremy Nicholson

Implantable loop recorder can help diagnose heart rhythm abnormalities in SSc patients

BNPs have potential to enable early diagnosis, long-term treatment of RA with minimal side effects

Type 1 diabetes occurs more frequently in patients with JIA

Anti-CPP presence in bloodstream of RA patients correlates with drug response

Advanced imaging technique helps predict recovery in concussion patients

Antibody-positive patients treated with infliximab less likely to benefit from infliximab biosimilar

Study finds non-disclosure of sexual orientation among behaviorally bisexual men

Air pollution exposure may have direct role in triggering lupus among children and adolescents

Scientists discover new ZBTB7A gene mutation that promotes growth of cancer cells

Pre-procedure medication regimen could lower incidence of hospital readmission in lung caner patients

Childhood exposure to chronic parental domestic violence linked to suicide attempts among adults

Minimal zinc deficiency can impede human and animal health

Scientists map Zika and dengue-transmitting mosquitoes in U.S. counties

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

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