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Researchers identify three single-driver genetic alterations that occur in neuroepithelial tumors

The St. Jude Children's Research Hospital – Washington University Pediatric Cancer Genome Project (PCGP) has identified critical driver genes that account for disease-related alterations in a range of uncommon low-grade neuroepithelial tumors.

26 Jan 2016

Using Single-Molecule Studies to Understand Cellular Processes: An Interview with Professor W. E. Moerner

Single fluorescent molecules provide a local nanometer-sized probe of complex systems. We can measure the motion of the single molecule, use them to achieve imaging on a scale down to 20 nanometers, or we can infer aspects of the behaviour of the object under study by the details of the light that is emitted.

From Pittcon 26 Jan 2016

Monitoring HBcrAg levels could help optimise PEG-IFN therapy

Serum hepatitis B core-related antigen could serve as a quantitative marker of response to pegylated interferon therapy in patients with chronic hepatitis B virus infection positive for hepatitis B e antigen (HBeAg), findings indicate.

26 Jan 2016

Rescue TDF monotherapy effective in multidrug resistant chronic HBV

Researchers from the Republic of Korea say that rescue therapy with tenofovir disoproxil fumarate alone is an appropriate option for patients with multidrug resistant chronic hepatitis B virus infection.

26 Jan 2016

Palonosetron effective anti-emetic for paediatric chemotherapy patients

Palonosetron 20 μg/kg is noninferior to ondansetron for the control of chemotherapy-induced vomiting and nausea during the acute phase of the first treatment cycle in paediatric patients with cancer, research shows.

26 Jan 2016

STAT4 variant predicts HBV IFNα response

Variation in the STAT4 gene is associated with response to interferon (IFN)α therapy in patients with hepatitis B e antigen-positive chronic hepatitis B virus infection, suggests research published in Hepatology.

26 Jan 2016

The mechanism behind protective cells protecting themselves

Researchers at St. Jude Children's Research Hospital have discovered the mechanism by which immune cells called regulatory T cells keep themselves intact and functional during their demanding task of holding the immune system in check. Such T cells are key to preventing the immune system from attacking the body in autoimmune disease.

26 Jan 2016

Using acidity to detect cancer

Normally, tissues demonstrate a slightly acidic intracellular pH (pHi) and slightly alkaline extracellular pH (pHe). However, proliferating tissues demonstrate transient pH Gradient Reversal i.e. alkalinization of pHi and acidification of pHe.

26 Jan 2016

Preventing memory loss in Alzheimer's Disease, a new key mechanism

Neurons communicate with one another by synaptic connections, where information is exchanged from one neuron to its neighbor. These connections are not static, but are continuously modulated in response to the ongoing activity (or experience) of the neuron.

26 Jan 2016

Genetic code and epigenetics revealing adaption traits

A well-known songbird, the great tit, has revealed its genetic code, offering researchers new insight into how species adapt to a changing planet. Their initial findings suggest that epigenetics -- what's on rather than what's in the gene -- may play a key role in the evolution of memory and learning. And that's not just true for birds.

26 Jan 2016

New study aims to prevent chronic cardiac failure

Researchers at Osaka University clarified that the cell adhesion inhibition of periostin1 damages myocardinal cells, inducing compromised cardiac myocyte contractile force and myocytes death, leading to the onset of cardiac failure after AMI through the administration of periostin neutralizing antibodies they had developed on their own.

26 Jan 2016

Researchers call for monitoring of playground paints to reduce public health dangers

Playground equipment should be monitored more regularly to ensure toxic metals contained within paints do not present a danger to public and child health, a study recommends.

26 Jan 2016

Better universal healthcare needed to reduce CHE for low-income TB patients in China

Improved universal healthcare is urgently needed to lower catastrophic health expenditure (CHE) for low-income tuberculosis (TB) patients in China, according to a study published in the open access journal Infectious Diseases of Poverty.

25 Jan 2016

Chronic fatigue syndrome affects almost 2% of 16-year-olds

In what is believed to be the biggest study of chronic fatigue syndrome (CFS) -- also known as myalgic encephalomyelitis (ME) -- in children to date, researchers at the University of Bristol (UK), have found that almost 2 per cent of 16-year-olds have CFS lasting more than six months and nearly 3 per cent have CFS lasting more than three months (the UK definition).

25 Jan 2016

Simple blood test could help predict emergence of pre-eclampsia in pregnant women

Pre-eclampsia is a serious illness associated with pregnancy, which develops after twenty weeks and is associated with defective ingrowing of the placenta within the mother. The dangerous illness is both the second most frequent cause of death in pregnant women, and the reason for severe complications for mother and child, especially during premature births.

25 Jan 2016

Colorectal cancer in younger patients associated with more advanced disease but better survival

Nearly 15 percent of patients diagnosed with colorectal cancer were younger than 50, the age at which screening recommendations begin.

25 Jan 2016

Diet rich in fiber may reduce risk of developing lung disease

A diet rich in fiber may not only protect against diabetes and heart disease, it may reduce the risk of developing lung disease, according to new research published online, ahead of print in the Annals of the American Thoracic Society.

25 Jan 2016

Study identifies discrimination, alcohol and tobacco as major predictors of panic attacks in minority Americans

A new study has identified discrimination, alcohol and tobacco as significant predictors of minority Americans' experiencing panic attacks — fearful spells with psychological symptoms that last a few minutes and are often debilitating and disruptive.

25 Jan 2016

Specific genetic pattern in the womb could predict IVF treatment outcome

Fertility experts in Southampton and the Netherlands have identified a specific genetic pattern in the womb that could predict whether or not IVF treatment is likely to be successful.

25 Jan 2016

Opioid medication does not improve physical function in patients with neuropathic pain

Opioids such as morphine, codeine and Tylenol 3 can be effective for treating pain, however, a new University of Alberta study finds that patients with neuropathic pain taking opioids report no improvements in physical functioning compared to those who were not prescribed opioids.

25 Jan 2016

Medical Research News

Researchers identify three single-driver genetic alterations that occur in neuroepithelial tumors

Using Single-Molecule Studies to Understand Cellular Processes: An Interview with Professor W. E. Moerner

Monitoring HBcrAg levels could help optimise PEG-IFN therapy

Rescue TDF monotherapy effective in multidrug resistant chronic HBV

Palonosetron effective anti-emetic for paediatric chemotherapy patients

STAT4 variant predicts HBV IFNα response

The mechanism behind protective cells protecting themselves

Using acidity to detect cancer

Preventing memory loss in Alzheimer's Disease, a new key mechanism

Genetic code and epigenetics revealing adaption traits

New study aims to prevent chronic cardiac failure

Researchers call for monitoring of playground paints to reduce public health dangers

Better universal healthcare needed to reduce CHE for low-income TB patients in China

Chronic fatigue syndrome affects almost 2% of 16-year-olds

Simple blood test could help predict emergence of pre-eclampsia in pregnant women

Colorectal cancer in younger patients associated with more advanced disease but better survival

Diet rich in fiber may reduce risk of developing lung disease

Study identifies discrimination, alcohol and tobacco as major predictors of panic attacks in minority Americans

Specific genetic pattern in the womb could predict IVF treatment outcome

Opioid medication does not improve physical function in patients with neuropathic pain

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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