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Tandem myeloablative ASCT consolidation boosts neuroblastoma outcomes

Research presented at the American Society of Clinical Oncology annual conference suggests that consolidation therapy with tandem compared with single myeloablative autologous stem cell transplant can improve outcomes in paediatric patients with high-risk neuroblastoma.

12 Jun 2016

Individual patient meta-analysis supports tPA stroke benefits

The benefits of intravenous tissue plasminogen activator outweigh the risks in acute stroke patients treated within 4.5 hours of symptom onset, reports the Stroke Thrombolysis Trialists' Collaboration.

12 Jun 2016

Combining decongestion markers may guide HF hospital discharge

Patients hospitalised with acute heart failure who achieve good haemoconcentration in addition to a robust diuretic response are unlikely to be rehospitalised within the following 2 months, research suggests.

12 Jun 2016

ATACH-2 disputes intensive BP control benefits in acute ICH

Reducing systolic blood pressure to less than 140 mmHg has offered no benefits over standard care for patients with acute intracerebral haemorrhage in the ATACH-2 trial.

11 Jun 2016

CRP may guide vascular risk assessment in obese

Low C-reactive protein levels may identify obese people who are unlikely to develop cardiovascular complications over subsequent years, show data from the EPIC study.

11 Jun 2016

Immunoablation strengthens haemopoietic stem-cell transplantation effects in MS

Intensifying current transplant conditioning to remove rather than suppress immune cells ahead of autologous haematopoietic stem cell transplantation may result in long-term remission of multiple sclerosis, phase II trial findings show.

10 Jun 2016

About 30% of iPSCs not safe for clinical use, report multi-institutional researchers

As the promise of using regenerative stem cell therapies draws closer, a consortium of biomedical scientists reports about 30 percent of induced pluripotent stem cells they analyzed from 10 research institutions were genetically unstable and not safe for clinical use.

10 Jun 2016

Aspirin may increase likelihood of surviving colon cancer

It is well known that the drug ASA, also known internationally as Aspirin, has analgesic and fever-reducing properties. However, this drug may also increase the likelihood of surviving colon cancer.

10 Jun 2016

MRI-guided focal laser ablation could be feasible, safe in prostate cancer patients

Prostate cancer patients may soon have a new option to treat their disease: laser heat. UCLA researchers have found that focal laser ablation - the precise application of heat via laser to a tumor - is both feasible and safe in men with intermediate risk prostate cancer.

10 Jun 2016

NHS Health Checks may not be best option for preventing CVD in England

A University of Liverpool study published in the British Medical Journal has found the UK population's cardiovascular health is not being supported enough by the NHS Health Check programme.

10 Jun 2016

NIH awards grant to lay policy groundwork to translate genomics into clinical care

The National Institutes of Health has awarded the first-ever grant dedicated to laying the policy groundwork needed to translate genomic medicine into clinical application.

10 Jun 2016

New method helps speed up bacterial identification

Pinpointing the type of bacteria that are at the root of an infection in clinical samples removed from living tissues, such as blood, urine or joint fluids, to quickly identify the best anti-microbial therapy still poses a formidable challenge.

10 Jun 2016

Carfilzomib therapy shows promise for pre-kidney transplant patients

Early findings by researchers at the University of Cincinnati College of Medicine suggest that the use of a second generation cancer drug, carfilzomib, may provide an improved approach for the reduction of antibodies in potential kidney transplant candidates.

10 Jun 2016

RNA editing enzyme ADAR1 may play role in regeneration of leukemia stem cells

Cancer stem cells are like zombies — even after a tumor is destroyed, they can keep coming back. These cells have an unlimited capacity to regenerate themselves, making more cancer stem cells and more tumors.

10 Jun 2016

New qPAINT technology helps develop more precise, less expensive microscopes

Knowing the exact number of molecules located at specific junctures in cells can be a critical measure of health as well as disease. For example, abnormally high numbers of growth factor receptors on cells can be an indication of cancerous and precancerous states; specific proteins located at the junction where neurons connect in the brain may affect brain function as they accumulate or disperse.

10 Jun 2016

First limbal stem cell transplant performed in Ireland

On Tuesday 7th June 2016, the first Limbal Stem Cell transplant in Ireland was performed by Mr. William Power, Consultant Ophthalmologist at the Royal Victoria Eye and Ear Hospital in Dublin.

10 Jun 2016

Study: About 40% of Hispanic adults with colorectal cancer use CIH

A study of complementary and integrative health (CIH) use among Hispanic adults with colorectal cancer found that about 40% reported experience with CIH.

10 Jun 2016

Study captures interactions of HIV-infected immune cells in living animal

By watching brightly glowing HIV-infected immune cells move within mice, researchers at the Icahn School of Medicine at Mount Sinai have shown how infected immune cells latch onto an uninfected sister cell to directly transmit newly minted viral particles.

10 Jun 2016

Researchers discover AF1q protein linked to multiple myeloma, EMD

A group of researchers from the University of Louisville, Japan and Austria is the first to identify a protein, AF1q, associated with multiple myeloma and a condition that occurs in approximately one-fourth of very aggressive multiple myeloma, extramedullary disease or EMD.

10 Jun 2016

Study highlights role of intestinal calcium absorption in kidney stone formation

Measuring intestinal calcium absorption may help to identify individuals who are prone to develop kidney stones, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology.

10 Jun 2016