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Special receptor signalling mediates astrocytic hyperactivity in Alzheimer's disease mouse model

It has long been known that astrocytes change their shapes as a consequence of Alzheimer's. Cells located near the "plaques", as the protein deposits typical for this disease are called, grow in size and form additional extensions.

20 Nov 2014

New nutrition standards do not limit added sugar in school meals

New federal regulations requiring school meals to contain more whole grains, less saturated fat and more fruits and vegetables, while perhaps improving some aspects of the food being served at schools across the United States, may also be perpetuating eating habits linked to obesity, diabetes and other diet-related diseases, an analysis by Johns Hopkins Bloomberg School of Public Health researchers has found.

20 Nov 2014

Stress can be helpful when it comes to emotionally relevant information

Retrieving memory content under stress does not work very well. However, stress can be helpful when it comes to saving new information -- especially those that are emotionally relevant in stressful situations.

20 Nov 2014

TSRI study examines body’s own response against chronic protein misfolding

“Protein misfolding” diseases such as cystic fibrosis and Alzheimer’s may be seriously exacerbated by the body’s own response against that misfolding, according to a new study led by scientists at The Scripps Research Institute.

20 Nov 2014

CHOP presents new findings on pediatric cardiovascular disease at AHA Scientific Sessions

Physician-researchers from the Cardiac Center at The Children's Hospital of Philadelphia presented new findings on pediatric cardiovascular disease at the American Heart Association's Scientific Sessions 2014 in Chicago.

20 Nov 2014

People who handle complex jobs may have longer-lasting memory and thinking abilities

People whose jobs require more complex work with other people, such as social workers and lawyers, or with data, like architects or graphic designers, may end up having longer-lasting memory and thinking abilities compared to people who do less complex work, according to research published in the November 19, 2014, online issue of Neurology, the medical journal of the American Academy of Neurology.

20 Nov 2014

Better behavioral health management can improve health, lower costs

More than a third of hospitalization costs in 13 low-income New Jersey communities are associated with behavioral health conditions, including mental health disorders and substance use, accounting for $880 million in annual inpatient costs, according to a new Rutgers study.

20 Nov 2014

Minimum legal drinking age legislation can have major impact on young drivers in Canada

Minimum legal drinking age legislation in Canada can have a major impact on young drivers, according to a new study from the Northern Medical Program at the University of Northern British Columbia. Drivers just older than the legal age had a significant increase in motor vehicle crashes compared to those immediately under the restriction.

20 Nov 2014

Majority of kidney dialysis patients not adequately prepared for emergency or natural disaster

Eighty percent of kidney dialysis patients surveyed were not adequately prepared in the event of an emergency or natural disaster that shut down their dialysis center.

20 Nov 2014

Study shows how stem cells can help regenerate damaged muscle after heart attack

Delivering stem cell factor directly into damaged heart muscle after a heart attack may help repair and regenerate injured tissue, according to a study led by researchers from Icahn School of Medicine at Mount Sinai presented November 18 at the American Heart Association Scientific Sessions 2014 in Chicago, IL.

19 Nov 2014

Changes in one gene can influence person's cholesterol levels from midlife through late life

It's known that cholesterol levels typically rise as people age and that high cholesterol levels are associated with increased risk of cardiovascular disease. What's less known is that cholesterol levels begin to decline the more a person ages. Recently, researchers from the University of Texas Medical Branch at Galveston and the University of Kentucky found that differences in one gene can influence a person's cholesterol levels from midlife to late life.

19 Nov 2014

More breast cancer patients choosing to undergo mastectomy, finds Vanderbilt study

Far more breast cancer patients are choosing to undergo mastectomy, including removal of both breasts, instead of choosing breast conservation surgery even when they have early stage disease that is confined to one breast, a Vanderbilt study shows. In the past decade, there have also been marked trends toward higher proportions of women opting for breast reconstruction.

19 Nov 2014

Targeting bacterial motility to combat chronic respiratory disease

Mycoplasma gallisepticum causes chronic respiratory disease in birds. The illness particularly affects domestic chicken and turkey flocks. The bacteria are especially life-threatening for the animals when they occur in combination with other infections. In order to control the spread of the disease, poultry farms in the EU must be proven free from Mycoplasma gallisepticum or face being closed.

19 Nov 2014

Gene therapy transforms life for men with severe form of hemophilia B

Gene therapy developed at St. Jude Children's Research Hospital, University College London and the Royal Free Hospital has transformed life for men with a severe form of hemophilia B by providing a safe, reliable source of the blood clotting protein Factor IX that has allowed some to adopt a more active lifestyle, researchers reported.

19 Nov 2014

Scientists unravel molecular mechanisms that drive ferroptosis signaling

Ferroptosis is a recently recognized form of regulated necrosis. Up until now, this form of cell death has only been thought to be a possible therapeutic approach to treat tumour cells. Yet, ferroptosis also occurs in non-transformed tissues as demonstrated by this study, thus implicating this cell death pathway in the development of a wide range of pathological conditions. More specifically, the deletion of the ferroptosis-regulating enzyme Gpx4 in a pre-clinical model results in high ferroptosis rates in kidney tubular epithelial cells causing acute renal failure.

19 Nov 2014

New method could make Ebola surveillance quicker, cheaper for West African nations

A new method for examining the Ebola virus genome could make surveillance quicker and cheaper for West African nations, and help detect new forms of the virus. The detailed procedure is being shared with the research community along with the study paper, which is freely available in the open access journal Genome Biology.

19 Nov 2014

Scientists discover second wave of heart muscle inflammation within a week after heart attack

Results of a new study challenge the current consensus in cardiology that peak myocardial edema, or heart muscle swelling, only occurs just after a myocardial infarction, or heart attack. In the study, presented as a Late-Breaking Clinical Trial at the American Heart Association Scientific Sessions 2014 and published simultaneously in the Journal of the American College of Cardiology, scientists discovered a second wave of swelling and inflammation occurs within a week of a heart attack.

19 Nov 2014

Medical Research News

Special receptor signalling mediates astrocytic hyperactivity in Alzheimer's disease mouse model

New nutrition standards do not limit added sugar in school meals

Stress can be helpful when it comes to emotionally relevant information

TSRI study examines body’s own response against chronic protein misfolding

CHOP presents new findings on pediatric cardiovascular disease at AHA Scientific Sessions

People who handle complex jobs may have longer-lasting memory and thinking abilities

Better behavioral health management can improve health, lower costs

Minimum legal drinking age legislation can have major impact on young drivers in Canada

Majority of kidney dialysis patients not adequately prepared for emergency or natural disaster

Study shows how stem cells can help regenerate damaged muscle after heart attack

Changes in one gene can influence person's cholesterol levels from midlife through late life

More breast cancer patients choosing to undergo mastectomy, finds Vanderbilt study

Targeting bacterial motility to combat chronic respiratory disease

Gene therapy transforms life for men with severe form of hemophilia B

Scientists unravel molecular mechanisms that drive ferroptosis signaling

New method could make Ebola surveillance quicker, cheaper for West African nations

Scientists discover second wave of heart muscle inflammation within a week after heart attack

Leaders in research hope to uncover promising drugs in pharma libraries, conduct clinical trials

Omega-3 benefits may be sustained in early psychosis

Strict monitoring of lithium levels urged

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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