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Unexpected toxicity of pazopanib/pemetrexed in NSCLC halts study

A phase II study comparing first-line combination pazopanib/pemetrexed chemotherapy with the standard cisplatin/pemetrexed treatment in non-small-cell lung cancer was terminated early owing to an increased frequency of adverse events in the experimental arm.

17 Dec 2013

Rich club disconnectivity may be ‘core’ schizophrenia feature

The impaired “rich club” connectivity observed in the brains of patients with schizophrenia is also present in their unaffected siblings, report researchers.

17 Dec 2013

Researchers use ATX-Red AR-2 as new imaging agent to illuminate tumors

Researchers from Echelon Biosciences, Inc. and collaborators from the University of Utah report the use of ATX-Red AR-2 as a new imaging agent that effectively illuminates tumors.

17 Dec 2013

Scientists reveal how MRSA strain rapidly rises to prominence

Scientists believe they have an explanation for how the most common strain of methicillin-resistant Staphylococcus aureus rapidly rose to prominence. Research published in mBio-, the online open-access journal of the American Society for Microbiology, suggests that the strain recently acquired a number of genes from common skin bacteria that allow it to grow and thrive on the skin where other strains of MRSA cannot.

17 Dec 2013

Researchers discover direct evidence of genetic overlap between cognitive ability and schizophrenia

Investigators at The Feinstein Institute for Medical Research have discovered for the first time, direct evidence of a genetic overlap between schizophrenia and general cognitive ability. The findings are published online in Molecular Psychiatry.

17 Dec 2013

Toddlers’ bedtime resistance may contribute to sleep problems

The bedtime you select for your toddler may be out of sync with his or her internal body clock, which can contribute to difficulties for youngsters attempting to settle in for the night, according to a new University of Colorado Boulder study.

17 Dec 2013

Study reveals that two wastewater treatment plants in China fail to kill antibiotic-resistant bacteria

Tests at two wastewater treatment plants in northern China revealed antibiotic-resistant bacteria were not only escaping purification but also breeding and spreading their dangerous cargo.

17 Dec 2013

European team experts to explore role of neighborhood in everyday lives of people with dementia

A European team of experts led by The University of Manchester will explore, investigate and evaluate the role of the neighbourhood in the everyday lives of people with dementia and their families in a new research project announced during the G8 dementia summit today (11 December).

17 Dec 2013

Investigators, CTUs chosen to lead five HIV/AIDS clinical trials networks through 2021

Principal investigators and clinical trials units have been chosen to lead and conduct the research of five HIV/AIDS clinical trials networks through 2021. The effort is directed and funded by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health. Total funding for the networks' leadership and the CTUs is expected to reach $225 million in 2014, the first year of operation.

17 Dec 2013

Research finds link between opioid-sparing technique and reduced progression of prostate cancer

The methods used to anesthetize prostate cancer patients and control pain when their prostate glands are surgically removed for adenocarcinoma may affect their long-term cancer outcomes, a study led by Mayo Clinic has found. Opioids, painkillers commonly given during and after surgery, may suppress the immune system's ability to fight cancer cells.

17 Dec 2013

Poland's entry into EU may have led to consequence of increasing allergies in rural villages

Poland's entry into the EU may have had the surprising consequence of increasing allergies in rural villages, according to a new study. Surveys show that the prevalence of atopy, a predisposition towards allergic reactions, jumped from seven per cent to 20 per cent in villages in southwest Poland between 2003 and 2012.

17 Dec 2013

Minorities who are at highest risk of diabetes may benefit from beverage sugar tax

Taxing sugar-sweetened beverages is likely to decrease consumption, resulting in lower rates of diabetes and heart disease, and these health benefits are expected to be greatest for the low-income, Hispanic and African-American Californians who are at highest risk of diabetes, according to a new analysis led by researchers at UC San Francisco.

17 Dec 2013

Researchers confirm link between contrast agent and abnormalities on brain MRI

For the first time, researchers have confirmed an association between a common magnetic resonance imaging (MRI) contrast agent and abnormalities on brain MRI, according to a new study published online in the journal Radiology. The new study raises the possibility that a toxic component of the contrast agent may remain in the body long after administration.

17 Dec 2013

Mirimus develops enhanced tools for reversible gene suppression

Over the last decades, RNA interference (RNAi) has become an indispensable tool for functional genetic studies by harnessing the power of a cell intrinsic mechanism enabling reversible gene silencing.

17 Dec 2013

Research on neurofeedback training proves to improve attention, working memory performance

The Distinguished Professor Shu-Lan Hsieh's research on neurofeedback training has proven to improve attention and working memory performance, National Cheng Kung University revealed recently.

17 Dec 2013

New comprehensive edition for neurologists provides invaluable source of reference

A new comprehensive edition of a standard work, detailing and illustrating the organization, structure, function and connectivity of all individual brainstem nuclei. For neuroscientists and neurologists this atlas provides an invaluable and complete source of reference for both their scientific research and everyday clinical practice.

17 Dec 2013

Scientists identify protein complex essential for jumpstarting immune response during infection

St. Jude Children's Research Hospital scientists have identified a protein complex that is essential for jumpstarting the immune response during the critical first 24 hours of an infection. The research appears in the current issue of the scientific journal Immunity.

17 Dec 2013

Self-affirmation can improve cognitive function, behavioral outcomes of people in poverty

For people in poverty, remembering better times - such as past success - improves brain functioning by several IQ points and increases their willingness to seek help from crucial aid services, a new study finds.

17 Dec 2013

Researchers identify potential biomarker to predict developmental problems in premature infants

Researchers have identified a potential biomarker for predicting whether a premature infant is at high risk for motor development problems, according to a study published online in the journal Radiology.

17 Dec 2013

Taking simple steps to stay healthy while traveling can make holidays more enjoyable, says expert

Traveling long distances during the holidays -- whether by car, plane or train -- is a common custom for many Americans, but taking health precautions for the journey isn't often at the top of to-do lists. Taking some simple steps to stay healthy while traveling can make the holidays more enjoyable and safe, according to a Mayo Clinic expert.

17 Dec 2013

Medical Research News

Unexpected toxicity of pazopanib/pemetrexed in NSCLC halts study

Rich club disconnectivity may be ‘core’ schizophrenia feature

Researchers use ATX-Red AR-2 as new imaging agent to illuminate tumors

Scientists reveal how MRSA strain rapidly rises to prominence

Researchers discover direct evidence of genetic overlap between cognitive ability and schizophrenia

Toddlers’ bedtime resistance may contribute to sleep problems

Study reveals that two wastewater treatment plants in China fail to kill antibiotic-resistant bacteria

European team experts to explore role of neighborhood in everyday lives of people with dementia

Investigators, CTUs chosen to lead five HIV/AIDS clinical trials networks through 2021

Research finds link between opioid-sparing technique and reduced progression of prostate cancer

Poland's entry into EU may have led to consequence of increasing allergies in rural villages

Minorities who are at highest risk of diabetes may benefit from beverage sugar tax

Researchers confirm link between contrast agent and abnormalities on brain MRI

Mirimus develops enhanced tools for reversible gene suppression

Research on neurofeedback training proves to improve attention, working memory performance

New comprehensive edition for neurologists provides invaluable source of reference

Scientists identify protein complex essential for jumpstarting immune response during infection

Self-affirmation can improve cognitive function, behavioral outcomes of people in poverty

Researchers identify potential biomarker to predict developmental problems in premature infants

Taking simple steps to stay healthy while traveling can make holidays more enjoyable, says expert

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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