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Adjunctive drugs hasten sedation in the emergency department

Adding intravenous droperidol or olanzapine to midazolam shortens the time to adequate sedation in acutely agitated patients in the emergency department, show findings from a randomized controlled trial.

2 Oct 2012

HDL may protect against abdominal aortic aneurysm

High levels of high-density lipoprotein cholesterol inhibit the formation of abdominal aortic aneurysm, findings from experimental mouse models suggest.

2 Oct 2012

Comorbid ADHD, PTSD increases psychiatric disorder risk

Research findings show that comorbid post-traumatic stress disorder in children and young individuals with attention deficit hyperactivity disorder increases the likelihood for psychiatric disorders and psychosocial dysfunction.

2 Oct 2012

Respiratory infections provide urban asthma clue

Urban infants have a different pattern of viral respiratory illness from suburban infants, which could help explain why they are more likely to develop asthma, say US researchers.

2 Oct 2012

Steroid use during tonsillectomy does not raise excessive bleeding risk

Children who are given dexamethasone during tonsillectomy are not more likely to experience excessive bleeding after surgery than those who do not receive the steroid perioperatively, study findings suggest.

2 Oct 2012

$Stent fracture after stent implantation linked to thrombosis$

Stent fracture after stent implantation linked to thrombosis

Stent fracture after everolimus-eluting stent implantation occurs in 2.9% of lesions and is associated with a significantly increased rate of major adverse cardiac events, say researchers.

2 Oct 2012

Genetics, trauma independently influence subthreshold psychosis

Study findings published in Acta Psychiatrica Scandinavica confirm that both genetics and environmental factors such as trauma independently influence the development and persistence of subthreshold psychotic symptoms.

2 Oct 2012

Biopolar disorder screening uncovers hidden anxiety

Patients who receive a false-positive diagnosis during screening tests for bipolar disorder are likely to have an undiagnosed anxiety disorder, suggest findings published in the Journal of Affective Disorders.

2 Oct 2012

Mothers’ CD4 cells ‘remember’ their babies

A breakthrough in understanding a mother’s immune response during pregnancy suggests a new direction for treating autoimmune diseases.

2 Oct 2012

Moderate alcohol intake increases risk of AF in older people with heart disease, diabetes

Moderate alcohol consumption increases the risk of atrial fibrillation in older people with heart disease or advanced diabetes, says a study by McMaster researchers.

2 Oct 2012

European Drug Initiative on Channels and Transporters focuses on membrane proteins

The European Drug Initiative on Channels and Transporters (EDICT), which comes to an end this year, focused on membrane proteins. They make up a third of all proteins in every organism and play a key role in many human diseases.

2 Oct 2012

Hip resurfacing prone to early failure

Hip resurfacing – an alternative to hip replacement often recommended to younger patients – is prone to early failure in many instances, and should not be used in women, according to an Article published Online First in The Lancet.

2 Oct 2012

Trial evidence is mixed regarding digital nerve reconstruction

Evidence supporting various surgical and postsurgical interventions in digital nerve reconstruction is inconsistent or imprecise, research shows.

1 Oct 2012

GnRH agonist may protect breast cancer patient fertility

Treatment with a gonadotropin-releasing hormone agonist may reduce the risk for chemotherapy-induced amenorrhea, research shows.

1 Oct 2012

Incidence of esophageal, stomach cancers increased in AIDS

The risk for esophageal and stomach carcinomas, as well as non-Hodgkin lymphomas, is significantly increased in people with AIDS, although the incidence of lymphomas has decreased, the results of a US and UK study reveal.

1 Oct 2012

Prognosis still poor for EVB in cirrhosis

The current standard of care for esophageal variceal bleeding in liver cirrhosis is very effective at controlling bleeding but patient prognosis remains poor, say the authors of an Italian study.

1 Oct 2012

Hormone and androgen receptor genes combined affect sperm motility

The combination of alleles for genes encoding the follicle-stimulating hormone receptor and androgen receptor has a significant impact on sperm motility, emphasising the importance of the genes in sperm quality, say Greek scientists.

1 Oct 2012

Coding the way to better occupational allergy care

The 11th draft of the International Classification of Diseases, due to be released in 2015, will allow a much more detailed specification of occupational allergy and contact dermatitis than the current draft, say dermatologists involved in the revision.

1 Oct 2012

Multiple Epo doses with hypothermia offers neonate neuroprotection

Multiple doses of erythropoietin in combination with hypothermia could be neuroprotective in neonates with hypoxic‑ischemic encephalopathy, say researchers.

1 Oct 2012

New treatment target brings hope for scleroderma patients

Research presented at the European Academy of Dermatology and Venereology in Prague, Czech Republic, suggests that inhibition of the SMAD protein may be a viable therapeutic target in scleroderma patients.

1 Oct 2012