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Small molecule compound shows significant success in controlling polyomaviruses

A team of scientists reports that a small molecule compound showed significant success in controlling the infectivity and spread of three polyomaviruses in human cell cultures. To date there has been no medicine approved to treat such viruses, which prey on transplant recipients, people with HIV, and others whose immune systems have been weakened.

15 Nov 2013

Eating protein-rich breakfast improves appetite control throughout the morning

While Americans generally consume enough protein, they tend to eat a small amount at breakfast, moderate amounts at lunch, and the largest amount at dinner. New research presented today at The Obesity Society's annual scientific meeting in Atlanta shows that eating high protein sausage and egg-based breakfasts curbed hunger throughout the morning, compared with a low-protein breakfast (pancakes and syrup) or skipping breakfast, in 18-55-year-old women.

15 Nov 2013

Identifying 'sensome' of microglia could improve treatments for neurodegenerative disorders

Massachusetts General Hospital investigators have used a new sequencing method to identify a group of genes used by the brain's immune cells - called microglia - to sense pathogenic organisms, toxins or damaged cells that require their response.

15 Nov 2013

Medical researchers discover structure of potential drug target for rare genetic disease

Medical researchers at the University of Alberta have discovered the structure of a potential drug target for a rare genetic disease, paving the way for an alternative treatment for the condition.

15 Nov 2013

Annexin A5 protein may have therapeutic potential for treatment of sepsis

Sepsis is the leading cause of in-hospital death and there is no specific treatment for it. Now, research led by Dr. Qingping Feng of Western University (London, Canada) suggests a protein called recombinant human annexin A5 may have therapeutic potential for the treatment of this disease. The paper is published in advance, online in Critical Care Medicine.

15 Nov 2013

When schools adopt healthful nutrition policies and practices, kids' diets improve

When schools adopt healthful nutrition policies and practices, kids' diets improve. According to new research led by Michigan State University and published in the current issue of Childhood Obesity, when schools offered snacks in lunchtime a la carte or vending that were mostly or entirely healthful, students responded with improvements in their diets, said Katherine Alaimo, MSU associate professor of food, science and human nutrition.

15 Nov 2013

Spirituality in teens linked with increased positive social behaviors, reduced narcissism

If the spirit is truly willing, perhaps the flesh is not so weak, after all. Increased spirituality in teens undergoing substance abuse treatment is associated with greater likelihood of abstinence (as measured by toxicology screens), increased positive social behaviors, and reduced narcissism, according to a study by researchers from The University of Akron, Case Western Reserve University (CWRU) and Baylor University.

15 Nov 2013

Dermalogix awarded SBIR Phase II grant to develop topical drug candidate for atopic dermatitis

Signum Dermalogix, Inc. announced that the National Institute of Arthritis and Musculoskeletal and Skin Diseases awarded the company a Small Business Innovation Research Phase II grant totaling $1.6 million for the development of a topical drug candidate for atopic dermatitis.

15 Nov 2013

Global Genomics Group, Metabolon partner to discover novel targets for cardiovascular diseases

Global Genomics Group and Metabolon today announced that they have entered into a collaboration agreement to investigate biological networks and pathways in order to discover novel biomarkers and pharmaceutical targets for cardiovascular diseases.

15 Nov 2013

Findings provide insights into the factors that affect surgeons’ reactions to major surgical complications

Many surgeons are seriously affected on an emotional level by major surgical complications, and they often feel that institutional support is inadequate. Those are among the conclusions of a small study published recently in the BJS (British Journal of Surgery).

14 Nov 2013

LLN spirometry inadequate to detect airflow obstruction

Research published in Thorax indicates that use of a lower limit of normal spirometric threshold fails to identify a number of patients with airflow obstruction and chronic obstructive pulmonary disease.

14 Nov 2013

Gray matter changes reflect psychosis burden

Changes in gray matter volume may be associated with psychosis burden rather than clinical diagnosis, research suggests.

14 Nov 2013

Parkinson’s biomarker could be only skin deep

Deposits of α-synuclein in cutaneous nerves could represent a noninvasive biomarker for Parkinson’s disease, say researchers.

14 Nov 2013

Men’s cognitive advantage maintained in early bipolar disorder

Patients in the early stages of bipolar disorder show the same gender differences in cognitive functioning as mentally healthy individuals, findings from the STOP-EM trial show.

14 Nov 2013

Depression link to Parkinson’s risk bolstered

A large retrospective study supports the notion that depression may be an independent risk factor for Parkinson’s disease.

14 Nov 2013

Screening for nonmotor symptoms in early Parkinson’s urged

Nonmotor symptoms have a substantial impact on the health-related quality of life of patients with early Parkinson’s disease, research shows.

14 Nov 2013

Diagnosing influenza with rapid tests leads to more efficient care

When patients in the emergency department (ED) are diagnosed with influenza by means of a rapid test, they get fewer unnecessary antibiotics, are prescribed antiviral medications more frequently, and have fewer additional lab tests compared to patients diagnosed with influenza without testing, according to a new study. Published online in the Journal of the Pediatrics Infectious Diseases Society, the findings suggest that diagnosing influenza with a rapid diagnostic test leads to more appropriate, specific, and efficient care.

14 Nov 2013

Severe sepsis mortality rates decrease over the past 20 years

A recent study from Boston University School of Medicine and Boston Medical Center shows a significant decrease in severe sepsis mortality rates over the past 20 years. Looking at data from patients with severe sepsis enrolled in clinical trials, researchers found that in-hospital mortality rates decreased from 47 percent between 1991 and 1995 to 29 percent between 2006 and 2009, a time period when no new pharmacological treatments were developed for severe sepsis.

14 Nov 2013

Researchers generate most complete genome sequences from single cells and individual neurons

Researchers led by bioengineers at the University of California, San Diego have generated the most complete genome sequences from single E. coli cells and individual neurons from the human brain. The breakthrough comes from a new single-cell genome sequencing technique that confines genome amplification to fluid-filled wells with a volume of just 12 nanoliters.

14 Nov 2013

New research devises effective way to evaluate severity of pulmonary hypertension

An aim to improve the outlook for people suffering from pulmonary hypertension is the focus of research at Griffith University.

14 Nov 2013

Medical Research News

Small molecule compound shows significant success in controlling polyomaviruses

Eating protein-rich breakfast improves appetite control throughout the morning

Identifying 'sensome' of microglia could improve treatments for neurodegenerative disorders

Medical researchers discover structure of potential drug target for rare genetic disease

Annexin A5 protein may have therapeutic potential for treatment of sepsis

When schools adopt healthful nutrition policies and practices, kids' diets improve

Spirituality in teens linked with increased positive social behaviors, reduced narcissism

Dermalogix awarded SBIR Phase II grant to develop topical drug candidate for atopic dermatitis

Global Genomics Group, Metabolon partner to discover novel targets for cardiovascular diseases

Findings provide insights into the factors that affect surgeons’ reactions to major surgical complications

LLN spirometry inadequate to detect airflow obstruction

Gray matter changes reflect psychosis burden

Parkinson’s biomarker could be only skin deep

Men’s cognitive advantage maintained in early bipolar disorder

Depression link to Parkinson’s risk bolstered

Screening for nonmotor symptoms in early Parkinson’s urged

Diagnosing influenza with rapid tests leads to more efficient care

Severe sepsis mortality rates decrease over the past 20 years

Researchers generate most complete genome sequences from single cells and individual neurons

New research devises effective way to evaluate severity of pulmonary hypertension

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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