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TAILORED-Treatment project to increase effectiveness of antibiotics receives EU funding

The European Union has funded a 4 year project called TAILORED-Treatment with € 6.000.000,-. The main goal of TAILORED -Treatment is to establish a strategy that can be used to increase the effectiveness of antibiotic treatment, reduce any potential side-effects of therapy, and help limit the emergence of antimicrobial resistance in hospitalized children and adults. The project will be coordinated by Erasmus MC, Rotterdam, the Netherlands.

14 Nov 2013

Study reveals how cocaine permanently damages proteins in the body

A new study on cocaine, the notorious white powder illegally snorted, injected or smoked by nearly 2 million Americans, details how it may permanently damage proteins in the body. That information, gleaned from laboratory tests, could be used to potentially detect the drug in biofluids for weeks or months - instead of days - after use, say scientists. The findings, which appear in the ACS journal Chemical Research in Toxicology, could also help explain cocaine's long-term health effects.

14 Nov 2013

Research findings call for a rethinking of cancer genetics

Johns Hopkins researchers report that the deletion of any single gene in yeast cells puts pressure on the organism’s genome to compensate, leading to a mutation in another gene. Their discovery, which is likely applicable to human genetics because of the way DNA is conserved across species, could have significant consequences for the way genetic analysis is done in cancer and other areas of research, they say.

14 Nov 2013

Hormone therapy does not help menopausal women who do not have hot flashes

Hormones at menopause can help with sleep, memory, and more, but only when a woman also has hot flashes, find researchers at Helsinki University in Finland. Their study was published online today in Menopause, the journal of The North American Menopause Society (NAMS).

14 Nov 2013

Skeletal problems now added to list of diabetes complications

The list of complications from type 2 diabetes is long: vascular and heart disease, eye problems, nerve damage, kidney disease, hearing problems and Alzheimer's disease. Physicians have long thought of osteoporosis as another outcome. Based on a Mayo Clinic study published in the Journal of Bone and Mineral Research, that's confirmed: You can definitely add skeletal problems to that list.

14 Nov 2013

Novel IRL-1620 compound may be useful in treating Alzheimer's disease

The novel compound IRL-1620 may be useful in treating Alzheimer's disease as it has been shown to prevent cognitive impairment and oxidative stress in animal models. This research is being presented at the 2013 American Association of Pharmaceutical Scientists Annual Meeting and Exposition, the world's largest pharmaceutical sciences meeting, in San Antonio, Nov. 10-14.

14 Nov 2013

Mount Sinai researchers successfully test SUMO-1 gene therapy to reverse heart failure

Researchers at the Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai have successfully tested a powerful gene therapy, delivered directly into the heart, to reverse heart failure in large animal models.

14 Nov 2013

People with higher pulse pressure more likely to have Alzheimer's biomarkers in cerebral spinal fluid

People in middle age who have a high blood pressure measure called pulse pressure are more likely to have biomarkers of Alzheimer's disease in their spinal fluid than those with lower pulse pressure, according to research published in the November 13, 2013, online issue of Neurology, the medical journal of the American Academy of Neurology.

14 Nov 2013

Gluten in the diet may modify intestinal microbiome, increasing incidences of Type 1 diabetes

Research has shown that the intestinal microbiome plays a large role in the development of Type 1 diabetes. Now, researchers at Mayo Clinic have demonstrated that gluten in the diet may modify the intestinal microbiome, increasing incidences of Type 1 diabetes. The research was published Nov. 13, in the journal PLOS ONE.

14 Nov 2013

Research findings could help decrease risk of dengue

A study by an international team of researchers led by Anna M. Stewart Ibarra, Ph.D., of the Center for Global Health and Translational Science at SUNY Upstate Medical University, has provided public health officials with information that will help decrease the risk of dengue, a life-threatening mosquito-borne viral disease that is now one of the fastest spreading tropical diseases globally.

14 Nov 2013

Over 50% of nonsurgical patients prescribed opioids during hospitalizations, analysis finds

Amid a growing climate of concern regarding the overuse of opioid pain medications, a comprehensive analysis of more than 1 million hospital admissions has found that over 50 percent of all nonsurgical patients were prescribed opioids during their hospitalizations -- often at very high doses -- and that more than half of those exposed were still receiving these medications on the day they were discharged from the hospital.

14 Nov 2013

High-power blue laser gadgets can cause serious eye damage

A type of high-power blue laser toy readily available over the Internet and increasingly popular among male teens and young adults can cause serious, sometimes irreversible, eye damage, according to a report by investigators from Saudi Arabia’s King Khaled Eye Specialist Hospital and Johns Hopkins Medicine.

14 Nov 2013

New finding challenges current models about how the brain processes visual information

University of Arizona doctoral degree candidate Jay Sanguinetti has authored a new study, published online in the journal Psychological Science, that indicates that the brain processes and understands visusal input that we may never consciously perceive.

14 Nov 2013

Study shows that geranylgeraniol suppresses viability of human DU145 prostate carcinoma cells

Researchers at Texas Woman's University have shown that a diterpene geranylgeraniol found in linseed oil, Cedrela toona wood oil, sucupira branca fruit oil and more recently, annatto seed oil, suppressed the viability of human DU145 prostate carcinoma cells via cell cycle arrest at the G1 phase and the initiation of apoptosis.

14 Nov 2013

Friendly microbes in the guts of healthy children have numerous antibiotic resistance genes

Friendly microbes in the intestinal tracts (guts) of healthy American children have numerous antibiotic resistance genes, according to results of a pilot study by scientists at Washington University School of Medicine in St. Louis.

14 Nov 2013

Researchers study link between vision loss and Alzheimer's disease

An international team of researchers studying the link between vision loss and Alzheimer's disease report that the loss of a particular layer of retinal cells not previously investigated may reveal the disease's presence and provide a new way to track disease progression.

14 Nov 2013

New studies reveal links between social status, specific brain structures and activity

New studies released today reveal links between social status and specific brain structures and activity, particularly in the context of social stress. The findings were presented at Neuroscience 2013, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news about brain science and health.

14 Nov 2013

Leading pediatric health system to examine causes of divergence and variability

The Department of Defense has awarded Nemours a $3.9 million grant to evaluate how physicians use best practice guidelines and to consider strategies to maintain clinical skills and consistency of care. The study, which will examine care provided throughout Nemours' pediatric health system, could help the military reintegrate physicians after deployment and better understand how their time away from routine practice affects their clinical knowledge and skill.

14 Nov 2013

Study identifies patterns of brain activity associated with eating disorders

A growing body of evidence shows the impact of diet on brain function, and identifies patterns of brain activity associated with eating disorders such as binge eating and purging. The findings were presented at Neuroscience 2013, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news about brain science and health.

14 Nov 2013

African American men have higher risk of developing prostate cancer than European American men

African American men have a 60 percent higher risk of developing prostate cancer than European American men, and a 2.4 times higher risk of dying from the disease. Some of the reasons can be attributed to differences in screening practices and treatment, but further research is needed to determine more explicit explanations.

14 Nov 2013

Medical Research News

TAILORED-Treatment project to increase effectiveness of antibiotics receives EU funding

Study reveals how cocaine permanently damages proteins in the body

Research findings call for a rethinking of cancer genetics

Hormone therapy does not help menopausal women who do not have hot flashes

Skeletal problems now added to list of diabetes complications

Novel IRL-1620 compound may be useful in treating Alzheimer's disease

Mount Sinai researchers successfully test SUMO-1 gene therapy to reverse heart failure

People with higher pulse pressure more likely to have Alzheimer's biomarkers in cerebral spinal fluid

Gluten in the diet may modify intestinal microbiome, increasing incidences of Type 1 diabetes

Research findings could help decrease risk of dengue

Over 50% of nonsurgical patients prescribed opioids during hospitalizations, analysis finds

High-power blue laser gadgets can cause serious eye damage

New finding challenges current models about how the brain processes visual information

Study shows that geranylgeraniol suppresses viability of human DU145 prostate carcinoma cells

Friendly microbes in the guts of healthy children have numerous antibiotic resistance genes

Researchers study link between vision loss and Alzheimer's disease

New studies reveal links between social status, specific brain structures and activity

Leading pediatric health system to examine causes of divergence and variability

Study identifies patterns of brain activity associated with eating disorders

African American men have higher risk of developing prostate cancer than European American men

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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