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Four Geisinger Health System researchers receive $25M grant to initiate ClinGen Project

Four Geisinger Health System researchers have taken center stage in the national arena of genomics thanks to new funding from the National Human Genome Research Institute (NHGRI), an arm of the U.S. National Institutes of Health (NIH).

27 Sep 2013

Study indicates that RNA translation is dictated by translational hotspots

Protein synthesis in the extensions of nerve cells, called dendrites, underlies long-term memory formation in the brain, among other functions. "Thousands of messenger RNAs reside in dendrites, yet the dynamics of how multiple dendrite messenger RNAs translate into their final proteins remain elusive," says James Eberwine, PhD, professor of Pharmacology, Perelman School of Medicine at the University of Pennsylvania, and co-director of the Penn Genome Frontiers Institute.

27 Sep 2013

New hepatitis virus reported by scientists was a false alarm

The report by scientists of a new hepatitis virus earlier this year was a false alarm, according to UC San Francisco researchers who correctly identified the virus as a contaminant present in a type of glassware used in many research labs.

27 Sep 2013

Genes in mitochondria shape each person's risk for heart disease and diabetes

Genes in mitochondria, the "powerhouses" that turn sugar into energy in human cells, shape each person's risk for heart disease and diabetes, according to a study published recently by researchers at the University of Alabama at Birmingham in the Biochemical Journal.

27 Sep 2013

Scientists discover critical regulator for directing pluripotent stem cells to make blood-forming stem cells

Stem cell scientists have moved one step closer to producing blood-forming stem cells in a Petri dish by identifying a key regulator controlling their formation in the early embryo, shows research published online today in Cell.

27 Sep 2013

Intestinal mucus potentially improves life of people suffering from inflammatory bowel disease

Researchers at Institut Hospital del Mar d'Investigacions M-diques (IMIM) in Barcelona, in collaboration with the Icahn School of Medicine at Mount Sinai in New York and other U.S. Institutions, have found that intestinal mucus not only acts as a physical barrier against commensal bacteria and dietary antigens, but also prevents the onset of inflammatory reactions against these agents.

27 Sep 2013

New public resource to help researchers explore data from the NIH human microbiome project

The National Institutes of Health (NIH) has launched the first phase of the Microbiome Cloud Project (MCP), a collaboration with Amazon Web Services that aims to improve access to and analysis of data from the Human Microbiome Project (HMP).

27 Sep 2013

Folic acid deficiency may be associated with multi-generational impact on health

Folic acid deficiency can cause severe health problems in offspring, including spina bifida, heart defects and placental abnormalities. A study out today reveals that a mutation in a gene necessary for the metabolism of folic acid not only impacts the immediate offspring but can also have detrimental health effects on the next several generations.

27 Sep 2013

TSRI scientists discover process by which special immune cells in skin help heal wounds

Scientists at The Scripps Research Institute (TSRI) have discovered an important process by which special immune cells in the skin help heal wounds. They found that these skin-resident immune cells function as "first responders" to skin injuries in part by producing the molecule known as interleukin-17A (IL-17A), which wards off infection and promotes wound healing.

27 Sep 2013

Study shows certain brain cells play critical role in anorexia, bulimia, and binge eating disorder

Sixty years ago scientists could electrically stimulate a region of a mouse's brain causing the mouse to eat, whether hungry or not. Now researchers from UNC School of Medicine have pinpointed the precise cellular connections responsible for triggering that behavior.

27 Sep 2013

Scientists study genetic factors involved in complex diseases

Although heavily studied, the specific genetic causes of "complex diseases," a category of disorders which includes autism, diabetes and heart disease, are largely unknown due to byzantine genetic and environmental interactions.

27 Sep 2013

'Jekyll-and-Hyde' protein could be potent target for developing new cancer drugs

The mood changes of a 'Jekyll-and-Hyde' protein, which sometimes boosts tumour cell growth and at other times suppresses it, have been explained in a new study led by Oxford University researchers.

27 Sep 2013

Experiments with neutrons show antidepressant lithium accumulates strongly in white matter of the brain

At present lithium is most popular for its use in rechargeable batteries. But for decades now, lithium has also been used to treat various psychological diseases such as depressions, manias and bipolar disorders. But, the exact biological mode of action in certain brain regions has hardly been understood. It is well known that lithium lightens moods and reduces aggression potential.

27 Sep 2013

Pediatric TBI can cause significant deficits in working memory

Traumatic brain injury (TBI) during childhood can have long-term effects on cognitive and psychosocial functioning, including poor academic achievement. Pediatric TBI can cause significant deficits in working memory, as demonstrated in a study published in Journal of Neurotrauma, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers.

27 Sep 2013

Researchers to use state-of-the-art brain imaging to study mucopolysaccharidosis

A team of researchers will use state-of-the-art brain imaging to unlock the secrets of a genetic disease, mucopolysaccharidosis, in a landmark study the team hope will lead to new treatments for this devastating disease.

27 Sep 2013

Research on bone-derived hormone could lead to new treatments for memory loss, depression

Researchers from Columbia University Medical Center (CUMC) have found that the skeleton, acting through the bone-derived hormone osteocalcin, exerts a powerful influence on prenatal brain development and cognitive functions such as learning, memory, anxiety, and depression in adult mice.

27 Sep 2013

Medical Research News

Four Geisinger Health System researchers receive $25M grant to initiate ClinGen Project

Study indicates that RNA translation is dictated by translational hotspots

New hepatitis virus reported by scientists was a false alarm

Genes in mitochondria shape each person's risk for heart disease and diabetes

Scientists discover critical regulator for directing pluripotent stem cells to make blood-forming stem cells

Intestinal mucus potentially improves life of people suffering from inflammatory bowel disease

New public resource to help researchers explore data from the NIH human microbiome project

Folic acid deficiency may be associated with multi-generational impact on health

TSRI scientists discover process by which special immune cells in skin help heal wounds

Study shows certain brain cells play critical role in anorexia, bulimia, and binge eating disorder

Scientists study genetic factors involved in complex diseases

'Jekyll-and-Hyde' protein could be potent target for developing new cancer drugs

Experiments with neutrons show antidepressant lithium accumulates strongly in white matter of the brain

Pediatric TBI can cause significant deficits in working memory

Researchers to use state-of-the-art brain imaging to study mucopolysaccharidosis

Research on bone-derived hormone could lead to new treatments for memory loss, depression

Joslin gets NIH grant to study potential treatment for kidney disease in people with diabetes

Icotinib matches gefitinib in NSCLC second or third line

Chronic bronchitis linked to poor asthma outcomes

Drug misuse predicts protracted hospital stay for schizophrenia patients

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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