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Chemotherapy combination outcomes differ for aged, younger colon cancer patients

The combination of chemotherapies 5FU and oxaliplatin compared to 5FU alone after surgery for colon cancer decreases colon cancer recurrence and promotes longer survival for patients under 70 -- but not for those who are older, according to Mayo Clinic and Dana-Farber Cancer Institute scientists who will present their findings at the American Society of Clinical Oncology's (ASCO) annual meeting in Orlando, Fla.

1 Jun 2009

New pathology tests double sensitivity to detect bile duct and pancreatic cancers

Pancreatic cancer and bile duct cancer are difficult to diagnose and often fatal because they are discovered in the advanced stages of the disease. Researchers have developed new tests that double the ability to detect bile duct and pancreatic cancers, according to a Mayo Clinic study published in the June issue of Gastroenterology.

1 Jun 2009

Obesity predicts inadequate bowel prep at colonoscopy

Obesity is an independent predictor of inadequate bowel preparation at colonoscopy, and the presence of additional risk factors further increases the likelihood of a poorly cleansed colon, according to a new study in Clinical Gastroenterology and Hepatology, the official journal of the American Gastroenterological Association (AGA) Institute.

1 Jun 2009

Research links intestinal inflammation with systemic chromosome damage

UCLA scientists have linked for the first time intestinal inflammation with systemic chromosome damage in mice, a finding that may lead to the early identification and treatment of human inflammatory disorders, some of which increase risk for several types of cancer.

1 Jun 2009

Glucose metabolism and recidivism of severe violent crimes in alcohol intoxications

It is commonly known that alcoholism and alcohol intoxications are connected with severe violent crimes such as homicides. For instance, in Finland even 80 per cent of these crimes happen in alcohol intoxications. It has not, however, been clear why only a minority of alcoholics in intoxications become irritated and impulsively aggressive or even commit severe violent crimes.

1 Jun 2009

MicroRNAs grease the cell's circadian clockwork

Most of our cells possess an internal clock, a group of genes displaying a cyclic expression pattern that reaches a peak once a day. A large number of circadian genes are expressed by organs such as the liver, whose activity needs to be precisely regulated over the course of the day.

31 May 2009

Combination of gene therapy and induced pluripotent stem cells cure human genetic disease in vitro

A study led by researchers at the Salk Institute for Biological Studies, has catapulted the field of regenerative medicine significantly forward, proving in principle that a human genetic disease can be cured using a combination of gene therapy and induced pluripotent stem (iPS) cell technology. The study, published in the May 31, 2009 early online edition of Nature, is a major milestone on the path from the laboratory to the clinic.

31 May 2009

New research sheds light on ways to improve treatment for aggressive breast cancer

Changing the order that chemotherapy drugs are given to breast cancer patients before surgery makes treatment much more effective, according to trial results presented at the American Society of Clinical Oncology (ASCO) conference, today.

31 May 2009

Genetic profiling reveals genes active in the earliest brain circuit construction

Long before the brain's neurons can facilitate life's big decisions, they have to find their own destiny in the rapidly developing embryo.

31 May 2009

Better treatment selection and improved therapies hold the key to improving prognosis in acute heart failure

Today, acute heart failure represents the most common reason for hospitalisation in the over-65 population.

31 May 2009

Moderate alcohol consumption reduces risk of gallstones

Health researchers at the University of East Anglia (UEA) have found that drinking two units of alcohol per day reduces the risk of developing gallstones by a third.

31 May 2009

Low vitamin D levels in blacks could contribute to higher rates of cancer, other diseases, researcher says

Low vitamin D levels in blacks could contribute to health gaps between white and black U.S. residents, Michael Holick, a professor at Boston University and a vitamin D researcher, said recently, the GNS/Chicago Sun-Times reports.

28 May 2009

Warning on athletes’ use of prescription drugs

Athletes could be putting their lives at risk by doping themselves with powerful prescription drugs, a leading academic has warned. Professor Declan Naughton, Professor of Biomolecular Sciences at Kingston University in South West London, cautioned sportsmen and women against trying to improve their performance by taking drugs known as nitrites without clinical supervision.

28 May 2009

Genomic research lays groundwork for new approaches for treating, preventing skin diseases

The health of our skin - one of the body's first lines of defense against illness and injury - depends upon the delicate balance between our own cells and the millions of bacteria and other one-celled microbes that live on its surface.

28 May 2009

Adult bone marrow stem cells injected into skeletal muscle can repair heart tissue

University at Buffalo researchers have demonstrated for the first time that injecting adult bone marrow stem cells into skeletal muscle can repair cardiac tissue, reversing heart failure.

28 May 2009

Discovery of biochemical signals that help immune cells remember how to fight infection

Immunology researchers at UT Southwestern Medical Center have discovered how two biochemical signals play unique roles in promoting the development of a group of immune cells employed as tactical assassins.

28 May 2009

Many of the costs of gambling are hidden and crime-related

Researchers in New Zealand say many of the costs of gambling are hidden and a substantial amount of gambling is related to crime, is 'invisible' and is not reported to the authorities.

27 May 2009

Extra calories not lack of exercise causing obesity

New research from New Zealand has found that over-eating rather than lack of physical activity, is why Kiwis are pilling on the excess kilos.

27 May 2009

Experimental therapy uses immune system to boost cure rate in neuroblastoma

A multicenter research team has announced encouraging results for an experimental therapy using elements of the body's immune system to improve cure rates for children with neuroblastoma, a challenging cancer of the nervous system.

27 May 2009

Psychiatrists begin revising diagnostic manual for mental illnesses

Over the next 18 months, psychiatrists will revise the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders, which is used to determine how U.S. residents' mental health is assessed, diagnosed and treated, the Los Angeles Times reports.

27 May 2009

Medical Research News

Chemotherapy combination outcomes differ for aged, younger colon cancer patients

New pathology tests double sensitivity to detect bile duct and pancreatic cancers

Obesity predicts inadequate bowel prep at colonoscopy

Research links intestinal inflammation with systemic chromosome damage

Glucose metabolism and recidivism of severe violent crimes in alcohol intoxications

MicroRNAs grease the cell's circadian clockwork

Combination of gene therapy and induced pluripotent stem cells cure human genetic disease in vitro

New research sheds light on ways to improve treatment for aggressive breast cancer

Genetic profiling reveals genes active in the earliest brain circuit construction

Better treatment selection and improved therapies hold the key to improving prognosis in acute heart failure

Moderate alcohol consumption reduces risk of gallstones

Low vitamin D levels in blacks could contribute to higher rates of cancer, other diseases, researcher says

Warning on athletes’ use of prescription drugs

Genomic research lays groundwork for new approaches for treating, preventing skin diseases

Adult bone marrow stem cells injected into skeletal muscle can repair heart tissue

Discovery of biochemical signals that help immune cells remember how to fight infection

Many of the costs of gambling are hidden and crime-related

Extra calories not lack of exercise causing obesity

Experimental therapy uses immune system to boost cure rate in neuroblastoma

Psychiatrists begin revising diagnostic manual for mental illnesses

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

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