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Clusterin identified as key marker for aging in blood stem cells

In recent years, there has been a growing trend of an aging patient population and an increasing prevalence of age-associated diseases, underscoring the need for advancing research into the biological mechanisms of aging.

30 Apr 2025

High fructose diets impair brain function and appetite control, study shows

Review highlights how excessive fructose intake disrupts brain energy balance, appetite regulation, and cognitive function. Processed sources, such as sugary drinks, may overwhelm metabolic pathways and induce neuroinflammation, particularly during adolescence.

30 Apr 2025

Digital cognitive assessments may offer a feasible way to screen older adults for dementia

Many adults aged 65 and older never receive a cognitive check during regular primary care visits. This study assessed the feasibility and acceptability of implementing a digital cognitive assessment for Alzheimer disease and related dementias (ADRD) screening into primary care.

30 Apr 2025

What’s missing in plant-based nutrition research? A new review explains

A new scoping review reveals major inconsistencies in how plant-based diet diversity is defined, measured, and linked to health outcomes in high-income countries. The findings highlight a critical need for standard definitions and validated assessment tools in future research.

30 Apr 2025

NR2F1 promotes cataract formation by activating STAT3 pathway

Cataracts are a prevalent ocular condition characterized by a progressive decline in vision, ultimately leading to blindness.

30 Apr 2025

Loss of EU nurses after Brexit tied to 1,485 additional deaths annually

During the three years after the EU referendum poll, Brexit's impact on the NHS caused 1,485 additional deaths per year as a result of EU nurses leaving the UK following the referendum, according to a new study from the University of Surrey.

30 Apr 2025

Midlife exercise may help lower Alzheimer's risk

An increase in physical activity between the ages of 45 and 65 could help prevent Alzheimer's disease, while inactivity may be detrimental to brain health.

30 Apr 2025

Extreme temperatures drive people toward high-fat diets, study finds

Short-term exposure to extreme temperatures alters dietary patterns by increasing fat intake, even when total calorie consumption remains stable. This shift, driven by physiological appetite regulation, raises the risk of high-fat diets and diet-related diseases, especially among vulnerable groups.

30 Apr 2025

New protein target offers hope for treating high blood pressure and aortic aneurysms

Oxidative stress can occur when our cells are exposed to harmful molecules called "reactive oxygen species" over time. These reactive oxygen species can damage cells and are found in important disease states, such as high blood pressure and aortic aneurysms.

30 Apr 2025

Home injections for HIV treatment show equal safety and satisfaction

Long-acting injectable antiretroviral therapy (ART) can be administered at home to persons living with HIV as safely and effectively by a health care professional as in the clinic, with equally high patient satisfaction rates, according to a new study conducted by MUSC Health Infectious Diseases clinician Eric Meissner, M.D., Ph.D., an associate professor in the College of Medicine.

30 Apr 2025

Machine learning provide new insights into how the brain responds to heroin use

Object recognition software is used by law enforcement to help identify suspects, by self-driving cars to navigate roadways and by many consumers to unlock their cell phones or pay for their morning coffee.

30 Apr 2025

Higher biological age linked to increased dementia risk

People whose biological age is higher than their chronological age may be more likely to develop dementia than people whose biological age matches or is lower than their chronological age, according to a study published on April 30, 2025, online in Neurology, the medical journal of the American Academy of Neurology.

30 Apr 2025

Can folic acid prevent or promote breast cancer? It depends on dose and DNA

Folic acid plays a dual role in breast cancer depending on dose and context. While moderate intake may reduce risk, high levels or genetic variants disrupting metabolism may promote tumor progression via altered DNA methylation.

30 Apr 2025

Single DNA mutation disrupts tumor suppressor pathways in blood cancer

Australian researchers have discovered that a single mutation in the DNA sequence for a methylation enzyme dysregulates key tumor-suppressing pathways, opening up new avenues for blood cancer treatment.

30 Apr 2025

Study: Nicotine pouch use nearly doubles among U.S. high school students

The use of nicotine pouches - small, easily concealed sachets of nicotine and additives that are placed between the gum and lip - nearly doubled among U.S. high school students between 2023 and 2024, according to a new USC study.

30 Apr 2025

Mindfulness-based therapy found to decrease opioid cravings and improve emotional health

Researchers from the University of California San Diego have found that Mindfulness-Oriented Recovery Enhancement (MORE) can help rewire the brain's response to natural healthy pleasure, leading to improved mood, greater attention to positive experiences and reduced opioid cravings.

30 Apr 2025

Racial disparities in breast reconstruction persist despite ACA implementation

Despite steady increases in rates of immediate breast reconstruction (IBR) after mastectomy, racial disparities in IBR have persisted in the years since implementation of the Affordable Care Act (ACA), reports a study in the May issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

30 Apr 2025