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Tirzepatide reduces obesity-associated breast cancer growth in mouse model

The anti-obesity medication tirzepatide, marketed as Mounjaro for diabetes and Zepbound for obesity, reduced obesity-associated breast cancer growth in a mouse model, according to a study being presented Saturday at ENDO 2025, the Endocrine Society's annual meeting in San Francisco, Calif.

12 Jul 2025

Study reveals dopamine sends precise signals rather than broad brainwide messages

A new study from the University of Colorado Anschutz Medical Campus has upended decades of neuroscience dogma, revealing that dopamine, a neurotransmitter critical for movement, motivation, learning and mood, communicates in the brain with extraordinary precision, not broad diffusion as previously believed.

12 Jul 2025

HPV16 and 18 nearly eliminated in vaccinated Danish women but other high risk types persist

Among the more than 100 types of human papillomavirus (HPV), at least 14 are considered as 'high-risk' types which can cause (cervical) cancer.

12 Jul 2025

Mapping how major organs communicate during physiological stress in humans

How major organs work together to manage extreme physiological stresses such as lack of oxygen and sleep has been mapped for the first time by researchers from UCL and the University of Portsmouth.

12 Jul 2025

Oral health function linked to markers of lifestyle-related diseases in older adults

The term 'oral health' refers to the health of the mouth, teeth, gums, and other related structures, and it is closely linked with our well-being and quality of life.

12 Jul 2025

Pathogenic mechanisms of Fusobacterium nucleatum in colorectal cancer and emerging therapies

In recent years, the regulatory role of the gut microbiota in the initiation and progression of colorectal cancer (CRC) has attracted growing attention. Among the key microbial contributors, Fusobacterium nucleatum (Fn) has been identified as a critical pathogenic factor in CRC.

12 Jul 2025

Social media analysis reveals emotional burden of children with multiple health conditions

Children with multiple long-term health issues undergo severe emotional stress at the same time as they are trying to cope with the physical challenges of their condition, a study has found.

12 Jul 2025

Therapeutic potential of houttuynia cordata polysaccharide in H1N1 and MRSA-induced acute pneumonia

This new article publication from Acta Pharmaceutica Sinica B, discusses how an anti-complement homogeneous polysaccharide from Houttuynia cordata ameliorates acute pneumonia with H1N1 and MRSA coinfection through rectifying Treg/Th17 imbalance in the gut–lung axis and NLRP3 inflammasome activation.

12 Jul 2025

ALKBH3 regulates glycolysis and doxorubicin resistance in triple negative breast cancer

This new article publication from Acta Pharmaceutica Sinica B, discusses how ALKBH3-regulated m1A of ALDOA potentiates glycolysis and doxorubicin resistance of triple negative breast cancer cells.

12 Jul 2025

Stereotactic radiation shows promise for small cell lung cancer with brain metastases

A new study led by investigators from Mass General Brigham trialed stereotactic (targeted) brain-directed radiation in 100 patients with small cell lung cancer and brain metastases, finding they experienced positive outcomes that support use of targeted radiation in the future for such patients.

12 Jul 2025

Melatonin receptor signaling counters sleep fragmentation-mediated infertility in T2DM

This new article publication from Acta Pharmaceutica Sinica B, discusses how melatonin receptor 1a alleviates sleep fragmentation-aggravated testicular injury in T2DM by suppression of TAB1/TAK1 complex through FGFR1.

12 Jul 2025

CMD-OPT model enables discovery of potent and selective RIPK2 inhibitor for acute liver injury

This new article publication from Acta Pharmaceutica Sinica B, discusses how a CMD-OPT model enables the discovery of a potent and selective RIPK2 inhibitor as preclinical candidate for the treatment of acute liver injury.

12 Jul 2025

Prefrontal cortex RNA drives female-specific brain resilience to depression

A traditionally overlooked type of RNA plays an important role in promoting resilience to depression-but only in females.

12 Jul 2025

Exploring the roles of orphan nuclear receptors in MASLD pathogenesis

Metabolic dysfunction-associated steatotic liver disease (MASLD), affecting approximately 30% of the global population, represents a spectrum of liver disorders ranging from simple steatosis to metabolic dysfunction-associated steatohepatitis (MASH), fibrosis, and cirrhosis.

12 Jul 2025

Blastocystis infection found in nearly one in four schoolchildren in northeastern Gabon

Announcing a new article publication for Zoonoses journal. This study was aimed at assessing the prevalence of infection with Blastocystis, an intestinal protozoan parasite, among school-aged children, and to identify associated risk factors.

12 Jul 2025

Nearly one-third of UK maternal deaths tied to involvement of children's social care services

The involvement of children's social care services was a common factor in nearly a third of UK maternal deaths occurring during, or within a year of, pregnancy between 2014 and 2022, finds research published in the open access journal BMJ Medicine.

12 Jul 2025

Study shines new light on how harmful industries shape scientific narratives

A new study, published in Addiction, shines a light on how industries associated with health harms-such as tobacco, fossil fuels, and in this case, alcohol-can distort the evaluation of scientific research through industry-friendly commentary.

12 Jul 2025

Global project measures true cost of healthy diets

A decade-long project measuring access to healthy foods worldwide is wrapping up in August, after shedding new light on the scope and specifics of nutrition insecurity, kickstarting solutions, and shifting the conversation around the affordability of healthy diets.

12 Jul 2025

Osteoblast estrogen receptor signaling found essential for bone integrity

Estrogen plays an important role in keeping bones healthy. Now, researchers investigated how membrane-initiated estrogen receptor alpha (mERα) signaling in specific cell types of female mice affects bone health.

12 Jul 2025

Hepatitis C treatment gaps persist for children and new mothers

As the opioid epidemic has worsened in the United States, prevalence of hepatitis C has also increased. Hepatitis C is a bloodborne virus that damages the liver.

11 Jul 2025

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Medical Research News

Tirzepatide reduces obesity-associated breast cancer growth in mouse model

Study reveals dopamine sends precise signals rather than broad brainwide messages

HPV16 and 18 nearly eliminated in vaccinated Danish women but other high risk types persist

Mapping how major organs communicate during physiological stress in humans

Oral health function linked to markers of lifestyle-related diseases in older adults

Pathogenic mechanisms of Fusobacterium nucleatum in colorectal cancer and emerging therapies

Social media analysis reveals emotional burden of children with multiple health conditions

Therapeutic potential of houttuynia cordata polysaccharide in H1N1 and MRSA-induced acute pneumonia

ALKBH3 regulates glycolysis and doxorubicin resistance in triple negative breast cancer

Stereotactic radiation shows promise for small cell lung cancer with brain metastases

Melatonin receptor signaling counters sleep fragmentation-mediated infertility in T2DM

CMD-OPT model enables discovery of potent and selective RIPK2 inhibitor for acute liver injury

Prefrontal cortex RNA drives female-specific brain resilience to depression

Exploring the roles of orphan nuclear receptors in MASLD pathogenesis

Blastocystis infection found in nearly one in four schoolchildren in northeastern Gabon

Nearly one-third of UK maternal deaths tied to involvement of children's social care services

Study shines new light on how harmful industries shape scientific narratives

Global project measures true cost of healthy diets

Osteoblast estrogen receptor signaling found essential for bone integrity

Hepatitis C treatment gaps persist for children and new mothers

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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