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Potential therapeutic target for treating Huntington's disease

Researchers studying yeast cells have identified a metabolic enzyme as a potential therapeutic target for treating Huntington's disease, a fatal inherited neurodegenerative disorder for which there is currently no effective treatment. The group, whose results appear in the May issue of Nature Genetics, includes researchers from the University of Washington School of Medicine in Seattle and the University of Maryland School of Medicine in Baltimore.

6 Apr 2005

Novel method to reduce cat allergic reactions

Scientists have discovered a novel method to reduce cat allergic reactions by topping up the immune cells responsible for controlling them.

6 Apr 2005

Asthmatics naturally deficient in antiviral immunity

Asthmatics produce lower levels of a type of immune cell protein needed to fight off infection from colds and other viruses, scientists have discovered.

6 Apr 2005

Startling evidence that people can unconsciously learn complex motor behaviors by watching

It's widely accepted that people watching an expert golfer or carpenter can learn the procedural steps to a better golf swing or building a deck. However, researchers Andrew A.G. Mattar at McGill University and Paul L. Gribble of the University of Western Ontario have developed startling evidence that people can unconsciously learn complex motor behaviors by watching such performances.

6 Apr 2005

THC in marijuana may prevent hardening of the arteries

A study by Dr. Francois Mach, University Hospital Geneva, Switzerland, and colleagues has found that low doses of the main active ingredient in marijuana slowed the progression of hardening of the arteries in mice, but some experts are stressing that the finding does not mean people should smoke marijuana in hopes of getting the same benefit.

6 Apr 2005

SSRI antidepressants "hijack" dopamine signaling as well launching serotonin signals

Researchers have discovered that antidepressant drugs such as Prozac not only affect levels of the neurotransmitter serotonin in the brain, but also "hijack" dopamine signaling as well--causing it to launch serotonin signals. Their findings offer new insight into how Prozac and other "selective serotonin uptake inhibitors" (SSRIs) work and how they might cause problems in patients taking them.

6 Apr 2005

Micro-organisms in clouds could play a crucial role in the spread of disease

The radical theories about nanobacteria – micro-organisms considerably smaller than ordinary bacteria - in clouds are published in two recent articles in the Journal of Proteome Research by Dr Andrei P. Sommer of the University of Ulm, Germany, and Professor Chandra Wickramasinghe of Cardiff University, UK.

6 Apr 2005

Sensory deprivation reduces new cell size in the olfactory system

Sensory deprivation causes changes in new cell size and excitability in the olfactory system, which governs the ability to smell, according to a study in Neuron by a Yale School of Medicine researcher.

6 Apr 2005

Yeast discovery provides new insights into familial dysautonomia

A discovery in yeast that has important implications for finding a cure for a devastating disease of nerve cell failures -- called familial dysautonomia (FD) -- has been made by Cornell University researchers.

6 Apr 2005

No association found between diet and pancreatic cancer

According to researchers from the Harvard School of Public Health (HSPH), the risk of pancreatic cancer does not appear to be associated with dietary patterns.

5 Apr 2005

Research supports the practice of Pilates to achieve some health benefits

Pilates is a beneficial exercise to enhance flexibility and muscular fitness and endurance, particularly for intermediate and advanced practitioners, but may have limited potential to notably increase cardiovascular fitness and reduce body weight.

5 Apr 2005

DNA packaging linked with cancer

New laboratory findings at the University of Illinois at Chicago suggest that what lies outside cancer cells is at least as important as the genes inside in explaining a tumor's malignancy.

5 Apr 2005

Blue-green algae linked to Alzheimer's disease

An international team of researchers, including scientists from the University of Dundee have announced that cyanobacteria (blue-green algae) found throughout the world may produce a toxin linked to certain types of neurological disease.

5 Apr 2005

Scientist finds different paths lead to similar cognitive abilities

Despite the divergent evolutionary paths of dolphins and primates -- and their vastly different brains -- both have developed similar high-level cognitive abilities, says Emory University neuroscientist and behavioral biologist Lori Marino.

5 Apr 2005

Genetic testing could bolster radiotherapy's effectiveness against cancer

Obtaining a genetic picture of how a tumor will react to the many treatment techniques available could help doctors prescribe therapies customized for individual cancer patients' needs, suggests a Purdue University research team.

5 Apr 2005

Seven-year research project to expand the evidence base in dentistry

Washington Dental Service, the University of Washington School of Dentistry and the School of Dentistry at Oregon Health Sciences University are partnering in a seven-year research project to expand the evidence base in dentistry.

5 Apr 2005

Researchers have identified a new clinical syndrome

Researchers have identified a new clinical syndrome that produces serious and sometimes fatal symptoms in a variety of seemingly unrelated diseases. The syndrome, described in the April 6 issue of the Journal of the American Medical Association, is caused by hemolysis, the destruction of red blood cells.

5 Apr 2005

Vitamin E supplements speed up the development of latent cancers

Taking high-dose vitamin E supplements for an extended period doesn't protect against cancer; in fact, it may even speed up the development of latent cancers, according to a study by researchers from Hotel-Dieu de Quebec Research Centre and Universite Laval. Their results are published in the April issue of the prestigious Journal of the National Cancer Institute.

5 Apr 2005

How heart is formed in the embryo helps explain congenital heart disease

Children's Hospital of Pittsburgh Cardiologist Bradley B. Keller, MD, and his research team are discovering details in the lab that explain how the heart is formed in the embryo. This knowledge improves the chances of doctors identifying fetuses who can benefit from intervention to treat congenital defects.

5 Apr 2005

Metabolic side effects of antipsychotics are known, but rarely monitored

Psychiatrists are doing a “modest” job of monitoring for weight gain, diabetes and other metabolic problems that may result from use of the newer antipsychotics for schizophrenia, researchers say.

5 Apr 2005