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Analysis reveals the global burden of type 1 diabetes in adults aged 65 years and older

Analysis reveals the global burden of type 1 diabetes in adults aged 65 years and older

The number of people aged 65 and older with type 1 diabetes increased from 1.3 million in 1990 to 3.7 million in 2019, while death rates fell 25% from 4.7 per 100,000 population in 1990 to 3.5 in 2019, finds an analysis of data from over 200 countries and regions in The BMJ today.

12 Jun 2024

Low-birth-weight deliveries linked to cognitive decline in later life

Low-birth-weight deliveries linked to cognitive decline in later life

People who give birth to infants less than 5.5 pounds may be more likely to have memory and thinking problems later in life than people who give birth to infants who do not have a low birth weight, according to a study published in the June 12, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

12 Jun 2024

Gastric bypass maintains weight loss and diabetes remission over 15 years, study shows

Gastric bypass maintains weight loss and diabetes remission over 15 years, study shows

Roux-en-Y gastric bypass, a type of weight-loss surgery, kept type 2 diabetes in remission for up to 15 years and most of the weight off for up to 20 years in one of the largest long-term studies of patients undergoing the procedure.

12 Jun 2024

Mechanistic connections between vascular health and dementia risk in older adults

Mechanistic connections between vascular health and dementia risk in older adults

A new review paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 10, entitled, "Peripheral vascular dysfunction and the aging brain."

12 Jun 2024

Germ cells drive sex-dependent lifespan differences in vertebrate animals

Germ cells drive sex-dependent lifespan differences in vertebrate animals

Women live longer than men. This isn't unique to humans, either; we see this trend in a wide range of other animals.

12 Jun 2024

Frailty as a major predictor of postoperative outcomes in elderly non-cardiac surgery patients

Frailty as a major predictor of postoperative outcomes in elderly non-cardiac surgery patients

A new study of Medicare beneficiaries aged 65 and older undergoing non-cardiac surgeries has revealed that frailty is a significant predictor of postoperative outcomes, regardless of the type of surgery performed.

12 Jun 2024

Integration of genomics, epigenomics, and transcriptomics in understanding Alzheimer's pathogenesis

Integration of genomics, epigenomics, and transcriptomics in understanding Alzheimer's pathogenesis

With the advent of new omics technologies in recent years, there has been a deluge of complex, high-dimensional data on Alzheimer's disease (AD).

12 Jun 2024

New AARF-D award supports Temple researchers to explore synapse function in the aging brain

New AARF-D award supports Temple researchers to explore synapse function in the aging brain

Late-life depression is a major risk factor for Alzheimer's disease, in particular because it accelerates progression from mild cognitive impairment to dementia.

12 Jun 2024

Multi-center study validates systemic score in identifying high-risk patients with Still's disease

Multi-center study validates systemic score in identifying high-risk patients with Still's disease

A multi-centre, observational, prospective study was designed to evaluate the clinical usefulness of the systemic score in predicting life-threatening evolution – defined as the development of macrophage activation syndrome (MAS) and/or mortality.

12 Jun 2024

Nutrients deficiency pattern possible important risk factor for mortality in older adults with hypertension

Nutrients deficiency pattern possible important risk factor for mortality in older adults with hypertension

Researchers determine the impact of nutrient deficiencies on mortality risk in older adults with hypertension.

12 Jun 2024

Macrophages play an unexpected role in the complicated obesity-cancer connection

Macrophages play an unexpected role in the complicated obesity-cancer connection

Immune system cells called macrophages play an unexpected role in the complicated connection between obesity and cancer, a Vanderbilt University Medical Center-led research team has discovered.

12 Jun 2024

Study identifies genetic predictors of X chromosome loss in aging women

Study identifies genetic predictors of X chromosome loss in aging women

Researchers have identified inherited genetic variants that may predict the loss of one copy of a woman's two X chromosomes as she ages, a phenomenon known as mosaic loss of chromosome X, or mLOX.

12 Jun 2024

Climate change-related environmental stressors associated with increased CVD mortality

Climate change-related environmental stressors associated with increased CVD mortality

Cardiovascular disease (CVD) is the leading cause of death worldwide, accounting for approximately one in every three deaths, with more than 20 million deaths reported in 2021 according to a 2024 World Heart Federation report.

12 Jun 2024

Combining anlotinib with STUPP regimen improves survival in glioblastoma patients

Combining anlotinib with STUPP regimen improves survival in glioblastoma patients

Glioblastoma multiforme (GBM) is among the most aggressive forms of brain tumors, with few effective treatment options and a bleak prognosis.

12 Jun 2024

Inflammation in mid-life as a predictor of mobility decline in older age

Inflammation in mid-life as a predictor of mobility decline in older age

In a recent study published in the Journal of the American Geriatric Society, having high inflammation in mid-life was associated with a clinically meaningful slower gait speed - an indicator of mobility - 20 years later.

12 Jun 2024

Childhood sensitivity to parental praise predicts emotional development

Childhood sensitivity to parental praise predicts emotional development

A new study published in Developmental Science found that children who were more positively sensitive to their parents' praise when they were 3 years old had fewer behavioral and emotional problems when they were 5–7 years old.

12 Jun 2024

Psychiatric conditions double mortality risk in anorexia nervosa patients

Psychiatric conditions double mortality risk in anorexia nervosa patients

A new study published in the International Journal of Eating Disorders found that mortality rates are high in patients with anorexia nervosa and nearly double in the presence of psychiatric conditions.

12 Jun 2024

Low-cost quality improvement program lowers mortality in El Salvador's pediatric ICU

Low-cost quality improvement program lowers mortality in El Salvador's pediatric ICU

Pediatric intensive care units (PICUs) in low and middle-income countries see elevated mortality rates, often 10 times higher than those in high-income countries.

12 Jun 2024

Human antibodies show promise against Black widow spider venom

Human antibodies show promise against Black widow spider venom

There are various types of widow spiders, including black, red, and brown varieties in North and South America, the Australian redback spider, and several button spider species that inhabit South Africa.

12 Jun 2024

Chronic kidney disease may be linked with tooth loss in postmenopausal women

Chronic kidney disease may be linked with tooth loss in postmenopausal women

Kidneys play a critical role in overall health by removing waste products from the blood. When they fail to sufficiently filter out foreign elements, several serious, lifethreatening, medical conditions can result.

12 Jun 2024

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